Amlodipine Impurity N11 CAS 31259-91-3
| CAS No. | 31259-91-3 |
| Molecular Formula | C7H4Cl4 |
| Molecular Weight | 229.92 g/mol |
| Category | Pharmacopoeial Impurity Standards / EP Impurities |
| Availability | In Stock |
Chemical Structure
Description
The molecular framework of Amlodipine Impurity N11 (C7H4Cl4) is characterized by chlorine substitution, an aromatic ring system. In reversed-phase chromatography, its retention is governed primarily by the polarity and ionization state of its functional groups, which provides a practical basis for HPLC-UV/DAD or LC-MS method development. The aromatic system may exhibit native fluorescence, enabling detection with a fluorescence detector (FLD).
As a process- or degradation-related impurity, Amlodipine Impurity N11 (CAS 31259-91-3, C7H4Cl4) is essential for impurity profiling, related-substances testing, and forced-degradation studies in pharmaceutical development.
Recommended for quantitative analysis by HPLC, GC, LC-MS/MS, or GC-MS as an external calibration standard; it can also be used for spiked-recovery experiments, LOD/LOQ determination, and LC-MS/MS multiple-reaction-monitoring (MRM) calibration.
CATO manufactures Amlodipine Impurity N11 under ISO 17034:2016 accreditation with dual CNAS and ANAB accreditation. Each batch is characterized by orthogonal methods and supplied with a full Certificate of Analysis (COA), ensuring metrological traceability.
Physical & Chemical Properties
| Molecular Formula | C7H4Cl4 |
| Molecular Weight | 229.92 g/mol |
| Appearance | Off-white to pale yellow crystalline powder. (slight halide-like odor, low volatility) |
| Purity | 97%+ |
| Storage | Store at room temperature, keep tightly closed to prevent evaporation |
| Solubility (reference) | Soluble in methanol, acetonitrile, DMSO |
| Stability | May oxidize slowly on prolonged air exposure |
| Degree of Unsaturation (DBE) | 4.0 |
| UV Absorption | UV-absorbing |
| Structural Features | Aromatic ring present |
| CAS Registry Year (est.) | 1965 |
| Halogen Content | Cl-containing |
Related Amlodipine Standards
- Amlodipine Impurity 103 (CAS 53901-54-5)
- Amlodipine Impurity 88 (CAS CATO-C4X-109588)
- Amlodipine Impurity 40 (CAS CATO-C4X-109540)
- Amlodipine Impurity 120 (CAS CATO-C4X-1095120)
- Amlodipine Impurity 15 (CAS 2832100-50-0)
- Amlodipine Impurity N1 (CAS 58509-24-3)
- Amlodipine Impurity N15 (CAS 19532-97-9)
- Amlodipine Impurity N12 (CAS 88-66-4)
Recommended Standards
- 2,3,4,5-Tetrachlorotoluene (CAS 1006-32-2)
- 1-(2,2-Dibromoethenyl)-2,2,3,3-d4-cyclopropane (CAS 1184977-20-5)
- 2,3,5,6-Tetrachlorotoluene (CAS 1006-31-1)
- 1,2-Dibromo-3-methylbutane (CAS 10288-13-8)
- Sodium Valproate EP Impurity D (CAS 52061-75-3)
- Indocyanine Green Impurity 41 (CAS 2581870-51-9)
- Phosphoramidite Impurity 26 (CAS CATO-C4X-288626)
- Ethyl 4-hydroxy-2-(trifluoromethyl)nicotinate (CAS 172985-72-7)
- 2-Hydroxy-6-methylbenzoic Acid Ethyl Ester 6-Methylsalicylic Acid Ethyl Ester 6555-40-4 Ethyl 2-Hydroxy-6-methylbenzoate Ethyl 6-Methylsalicylate M1283 (CAS 6555-40-4)
- 1-cyclopropyl-2-(piperazin-1-yl)ethan-1-ol dihydrochloride (CAS 1461713-94-9)
- (S)-2-Amino-N-(3,4-dichlorobenzyl)-N-isopropyl-3-methylbutanamide (CAS 1307652-56-7)
- Flupirtine Impurity H (CAS 16013-85-7)
- 90206-23-8 1-(Butan-2-yl)-3-methyl-1H-pyrazol-5-amine DTXSID30599114 (CAS 90206-23-8)
- Semaglutide impurity 266 (CAS CATO-C4X-2226266)
Why CATO?
- ISO 17034 accredited reference material producer (CNAS + ANAB dual accreditation)
- 130,000+ catalog items in stock, COA supplied with every batch
- Worldwide shipping with full export documentation (HS code guidance available)
- Technical support: +86 18665070610 / Nicole.chen@cato-chem.com