4-Hydroxy Estrone CAS 3131-23-5
| CAS No. | 3131-23-5 |
| Molecular Formula | C18H22O3 |
| Molecular Weight | 286.37 g/mol |
| Category | Pharmaceutical Standards / API Standards |
| Availability | In Stock |
Chemical Structure
Description
The occurrence of 4-Hydroxy Estrone is closely related to a steroid core, a hydroxyl group, an ether linkage in its molecular formula, which determines its behaviour during synthesis, purification, or degradation.
4-Hydroxy Estrone (CAS 3131-23-5) is a high-purity analytical reference standard with the molecular formula C18H22O3 and a molecular weight of 286.37 g/mol.
Based on its molecular formula C18H22O3, 4-Hydroxy Estrone contains a steroid core, a hydroxyl group, an ether linkage; these features give the compound characteristic absorption bands in UV spectroscopy. The molecular weight of 286.37 g/mol is directly relevant to the identification of the molecular ion in mass spectrometry. The aromatic system may exhibit native fluorescence, enabling detection with a fluorescence detector (FLD).
This reference standard is suitable for quantitative analysis on major chromatographic platforms including HPLC, GC, LC-MS/MS, and GC-MS, serving as an external calibration standard or a system suitability test reference material.
As a certified reference material (CRM), 4-Hydroxy Estrone meets the metrological traceability requirements of ISO/IEC 17025 laboratories. Batch-to-batch consistency is monitored via control charts to guarantee comparable assigned values across lots.
Physical & Chemical Properties
| Molecular Formula | C18H22O3 |
| Molecular Weight | 286.37 g/mol |
| Appearance | Pale yellow to yellow crystalline powder |
| Purity | >95% |
| Storage | Store at 2-8°C, protect from light, keep sealed and dry |
| Solubility (reference) | Soluble in chloroform, dichloromethane, ethyl acetate, DMSO |
| Stability | May oxidize slowly on prolonged air exposure; Light-sensitive; avoid direct strong light |
| Degree of Unsaturation (DBE) | 8.0 |
| UV Absorption | UV-absorbing |
| Structural Features | Aromatic ring present |
| CAS Registry Year (est.) | 1957 |
Related Hydroxy Standards
- 6β-Hydroxy Estrone (CAS 1229-25-0)
- N1-(3-Hydroxy-4,4-dimethylpentyl)-N2-((tetrahydrofuran-2-yl)methyl)oxalamide (CAS 1396814-27-9)
- 6α-Hydroxy Estrone (CAS 1476-78-4)
- 1-(2-Hydroxy-3-(pyrrolidin-1-yl)propyl)-2-methyl-1H-indole-3-carbaldehyde (CAS 883543-75-7)
- 4-(3-Hydroxy-5-phenylpentyl)-2-methoxyphenol (CAS 402469-45-8)
- 2-Hydroxy Estrone-d4 (CAS 81586-97-2)
- 2-Hydroxy Estrone (CAS 362-06-1)
- Ethyl 4-Hydroxy-1-[(pivaloyloxy)methyl]cyclohexanecarboxylate (CAS 1956327-61-9)
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