Phentolamine Impurity 19 CAS CATO-C4X-224719
| CAS No. | CATO-C4X-224719 |
| Molecular Formula | C17H22N2O2 |
| Molecular Weight | 286.37 g/mol |
| Category | Pharmacopoeial Impurity Standards / EP Impurities |
| Availability | In Stock |
Chemical Structure
Description
The occurrence of Phentolamine Impurity 19 is closely related to a steroid core, an amide group, a hydroxyl group, an ether linkage in its molecular formula, which determines its behaviour during synthesis, purification, or degradation.
As a process- or degradation-related impurity, Phentolamine Impurity 19 (CAS CATO-C4X-224719, C17H22N2O2) is essential for impurity profiling, related-substances testing, and forced-degradation studies in pharmaceutical development.
Based on its molecular formula C17H22N2O2, Phentolamine Impurity 19 contains a steroid core, an amide group, a hydroxyl group, an ether linkage; these features give the compound characteristic absorption bands in UV spectroscopy. The molecular weight of 286.37 g/mol is directly relevant to the identification of the molecular ion in mass spectrometry. The presence of an aromatic ring or conjugated system gives the compound characteristic absorption bands in the UV-Vis region, making it well suited to UV or diode-array detection (DAD).
Recommended for quantitative analysis by HPLC, GC, LC-MS/MS, or GC-MS as an external calibration standard; it can also be used for spiked-recovery experiments, LOD/LOQ determination, and LC-MS/MS multiple-reaction-monitoring (MRM) calibration.
The assigned purity is verified by mass-balance and quantitative NMR (qNMR) approaches, with the expanded uncertainty reported at a 95% confidence level (k=2). Batch homogeneity and stability are independently assessed for every lot.
Physical & Chemical Properties
| Molecular Formula | C17H22N2O2 |
| Molecular Weight | 286.37 g/mol |
| Appearance | Pale yellow to yellow crystalline powder |
| Purity | ≥95% |
| Storage | Store at 2-8°C, protect from light, keep sealed and dry |
| Solubility (reference) | Soluble in DMSO, DMF, methanol |
| Stability | May oxidize slowly on prolonged air exposure; Light-sensitive; avoid direct strong light; Hygroscopic; reseal immediately after opening |
| Degree of Unsaturation (DBE) | 8.0 |
| UV Absorption | UV-absorbing |
| Structural Features | Aromatic ring present |
| Nitrogen Atoms | 2 |
Related Phentolamine Standards
- Phentolamine (CAS 50-60-2)
- Phentolamine Impurity 16 (CAS CATO-C4X-224716)
- Phentolamine Impurity 21 (CAS CATO-C4X-224721)
- Phentolamine Impurity 8 (CAS 2767988-83-8)
- Phentolamine Impurity 24 (CAS CATO-C4X-224724)
- Phentolamine Impurity 26 (CAS CATO-C4X-224726)
- Phentolamine Impurity 27 (CAS CATO-C4X-224727)
- Phentolamine Impurity 15 (CAS CATO-C4X-224715)
Recommended Standards
- Nicergoline Impurity 22 (CAS CATO-C4X-208522)
- 4-Hydroxy Estrone (CAS 3131-23-5)
- Nicergoline Impurity 12 (CAS 35121-60-9)
- 2-Hydroxy Estrone-d4 (CAS 81586-97-2)
- Paroxetine EP Impurity J HCl (CAS CATO-C4X-103572)
- Abacavir EP Impurity F (CAS 1443421-68-8)
- Olaparib Impurity 126 (CAS CATO-C4X-1135126)
- 2H-Benzimidazol-2-one (CAS 43135-91-7)
- Dicyclohexylamine (R)-3-(1-(tert-butoxycarbonyl)-1H-imidazol-4-yl)-2-((tert-butoxycarbonyl)amino)propanoate (CAS 1217849-01-8)
- 2-(4-Ethylpiperazin-1-yl)isonicotinimidamide dihydrochloride (CAS 1221725-56-9)
- Trimethyl(phenethoxy)silane (CAS 14629-58-4)
- 1,2,3,4,5,6,7,8-Octahydrophenanthrene-9-carboxylic acid (CAS 65805-80-3)
- 9-Hydroxy-4H-pyrimido[1,6-a]pyrimidin-4-one (CAS 123420-39-3)
- Rac1 Inhibitor F56, control peptide (CAS 1315378-77-8)
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