Nicergoline Impurity 12 CAS 35121-60-9
| CAS No. | 35121-60-9 |
| Molecular Formula | C17H22N2O2 |
| Molecular Weight | 286.37 g/mol |
| Category | Pharmacopoeial Impurity Standards / EP Impurities |
| Availability | In Stock |
Chemical Structure
Description
Recommended for quantitative analysis by HPLC, GC, LC-MS/MS, or GC-MS as an external calibration standard; it can also be used for spiked-recovery experiments, LOD/LOQ determination, and LC-MS/MS multiple-reaction-monitoring (MRM) calibration.
CATO supplies Nicergoline Impurity 12 (CAS 35121-60-9), a pharmacopoeial impurity reference standard (molecular formula C17H22N2O2, MW 286.37 g/mol) used for the identification and quantification of trace impurities in APIs.
Based on its molecular formula C17H22N2O2, Nicergoline Impurity 12 contains a steroid core, an amide group, a hydroxyl group, an ether linkage; these features give the compound characteristic absorption bands in UV spectroscopy. The molecular weight of 286.37 g/mol is directly relevant to the identification of the molecular ion in mass spectrometry. The high carbon-to-hydrogen ratio imparts good lipophilicity, allowing liquid-liquid extraction with non-polar solvents such as n-hexane or ethyl acetate.
As a certified reference material (CRM), Nicergoline Impurity 12 meets the metrological traceability requirements of ISO/IEC 17025 laboratories. Batch-to-batch consistency is monitored via control charts to guarantee comparable assigned values across lots.
Physical & Chemical Properties
| Molecular Formula | C17H22N2O2 |
| Molecular Weight | 286.37 g/mol |
| Appearance | Pale yellow to yellow crystalline powder |
| Purity | >95% |
| Storage | Store at 2-8°C, protect from light, keep sealed and dry |
| Solubility (reference) | Soluble in DMSO, DMF, methanol |
| Stability | May oxidize slowly on prolonged air exposure; Light-sensitive; avoid direct strong light; Hygroscopic; reseal immediately after opening |
| Degree of Unsaturation (DBE) | 8.0 |
| UV Absorption | UV-absorbing |
| Structural Features | Aromatic ring present |
| CAS Registry Year (est.) | 1967 |
| Nitrogen Atoms | 2 |
Related Nicergoline Standards
- Nicergoline Impurity 22 (CAS CATO-C4X-208522)
- Nicergoline Impurity 14 (CAS CATO-C4X-208514)
- Nicergoline Impurity 18 (CAS CATO-C4X-208518)
- Nicergoline EP Impurity C (CAS 35155-28-3)
- Nicergoline Impurity 11 (CAS CATO-C4X-208511)
- Nicergoline Impurity 9 (CAS 23495-65-0)
- Nicergoline Impurity 21 (CAS 23495-64-9)
- Nicergoline Impurity 20 (CAS CATO-C4X-208520)
Recommended Standards
- Neostigmine impurity 42 (CAS CATO-C4X-204242)
- Neostigmine impurity 41 (CAS CATO-C4X-204241)
- Phentolamine Impurity 19 (CAS CATO-C4X-224719)
- Neostigmine Impurity 27 (CAS 63468-95-1)
- Dapoxetine Impurity 106 (CAS CATO-C4X-1439106)
- Ivabradine Impurity 35 (CAS CATO-C4X-111935)
- Prasugrel Impurity 35 (CAS CATO-C4X-108635)
- 5-Methyl-N-(trimethylsilyl)isoxazol-3-amine (CAS 99356-57-7)
- Ethyl 3-[2-(3-piperidinyl)ethoxy]benzoatehydrochloride (CAS 1219980-78-5)
- 4-Hydroxy-3-nitro-5-propoxybenzaldehyde (CAS 871085-51-7)
- Tadalafil impurity 126 (CAS CATO-C4X-1087126)
- Atorvastatin-d5 Calcium Salt (CAS 222412-82-0)
- 4,6-Dichloropyridin-2-ol (CAS 68963-75-7)
- Peptide Fmoc-Thi-Thi-OH (CAS CATO-CPTD788552)
Why CATO?
- ISO 17034 accredited reference material producer (CNAS + ANAB dual accreditation)
- 130,000+ catalog items in stock, COA supplied with every batch
- Worldwide shipping with full export documentation (HS code guidance available)
- Technical support: +86 18665070610 / Nicole.chen@cato-chem.com