Rivaroxaban Impurity 137 CAS 3140-73-6
| CAS No. | 3140-73-6 |
| Molecular Formula | C5H6ClN3O2 |
| Molecular Weight | 175.57 g/mol |
| Category | Pharmacopoeial Impurity Standards / EP Impurities |
| Availability | In Stock |
Chemical Structure
Description
CATO supplies Rivaroxaban Impurity 137 (CAS 3140-73-6), a pharmacopoeial impurity reference standard (molecular formula C5H6ClN3O2, MW 175.57 g/mol) used for the identification and quantification of trace impurities in APIs.
Owing to an amide group, a carboxylic acid group, a hydroxyl group, an ether linkage, chlorine substitution, Rivaroxaban Impurity 137 is typically off-white to pale yellow crystalline powder. Its solid-state physicochemical attributes — including a molecular weight of 175.57 g/mol — guide the selection of appropriate sample preparation and analytical techniques. The presence of an aromatic ring or conjugated system gives the compound characteristic absorption bands in the UV-Vis region, making it well suited to UV or diode-array detection (DAD).
This reference standard supports related-substances testing and method development in line with ICH Q3A/Q3B guidance on impurity control, and is suitable for system suitability testing and forced-degradation studies.
As a certified reference material (CRM), Rivaroxaban Impurity 137 meets the metrological traceability requirements of ISO/IEC 17025 laboratories. Batch-to-batch consistency is monitored via control charts to guarantee comparable assigned values across lots.
Physical & Chemical Properties
| Molecular Formula | C5H6ClN3O2 |
| Molecular Weight | 175.57 g/mol |
| Appearance | Off-white to pale yellow crystalline powder. (slight halide-like odor, faint amine-like odor) |
| Purity | >95% |
| Storage | Store at 2-8°C, protect from light, keep sealed and dry, keep tightly closed to prevent evaporation |
| Solubility (reference) | Soluble in DMSO, DMF, methanol |
| Stability | May oxidize slowly on prolonged air exposure; Light-sensitive; avoid direct strong light; Hygroscopic; reseal immediately after opening; Contains ester bond; hydrolyzes under strong alkaline conditions |
| Degree of Unsaturation (DBE) | 4.0 |
| UV Absorption | UV-absorbing |
| CAS Registry Year (est.) | 1957 |
| Halogen Content | Cl-containing |
| Nitrogen Atoms | 3 |
Related Rivaroxaban Standards
- Rivaroxaban CMTCA Impurity (CAS 97799-98-9)
- Rivaroxaban Impurity 95 (CAS 4789-09-7)
- Rivaroxaban Impurity 103 (CAS 35475-03-7)
- Rivaroxaban Impurity 38 (CAS 29518-11-4)
- Rivaroxaban Impurity 53 (CAS 66357-41-3)
- Rivaroxaban Impurity 84 (CAS 2524-67-6)
- Rivaroxaban Impurity 112 (CAS 90564-02-6)
- Rivaroxaban Impurity 74 (CAS 113471-08-2)
Recommended Standards
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- Methyl 2-(3-(4-methoxyphenyl)cyclobutyl)acetate (CAS 2112670-21-8)
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- 5-(Furan-2-yl)picolinonitrile (CAS 619334-50-8)
- Fragment-[3-31]-Semaglutide (CAS CATO-C4X-2226113)
Why CATO?
- ISO 17034 accredited reference material producer (CNAS + ANAB dual accreditation)
- 130,000+ catalog items in stock, COA supplied with every batch
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- Technical support: +86 18665070610 / Nicole.chen@cato-chem.com