Rivaroxaban Impurity 84 CAS 2524-67-6
| CAS No. | 2524-67-6 |
| Molecular Formula | C10H14N2O |
| Molecular Weight | 178.23 g/mol |
| Category | Pharmacopoeial Impurity Standards / EP Impurities |
| Availability | In Stock |
Chemical Structure
Description
This reference standard supports related-substances testing and method development in line with ICH Q3A/Q3B guidance on impurity control, and is suitable for system suitability testing and forced-degradation studies.
As a process- or degradation-related impurity, Rivaroxaban Impurity 84 (CAS 2524-67-6, C10H14N2O) is essential for impurity profiling, related-substances testing, and forced-degradation studies in pharmaceutical development.
Owing to a nitrogen-containing heterocyclic scaffold, an amide group, a hydroxyl group, an ether linkage, Rivaroxaban Impurity 84 is typically off-white to pale yellow crystalline powder. Its solid-state physicochemical attributes — including a molecular weight of 178.23 g/mol — guide the selection of appropriate sample preparation and analytical techniques. The aromatic system may exhibit native fluorescence, enabling detection with a fluorescence detector (FLD).
The assigned purity is verified by mass-balance and quantitative NMR (qNMR) approaches, with the expanded uncertainty reported at a 95% confidence level (k=2). Batch homogeneity and stability are independently assessed for every lot.
Physical & Chemical Properties
| Molecular Formula | C10H14N2O |
| Molecular Weight | 178.23 g/mol |
| Appearance | Off-white to pale yellow crystalline powder. (faint amine-like odor) |
| Purity | 97%+ |
| Storage | Store at 2-8°C, protect from light |
| Solubility (reference) | Soluble in DMSO, DMF, methanol |
| Stability | Light-sensitive; avoid direct strong light |
| Degree of Unsaturation (DBE) | 5.0 |
| UV Absorption | UV-absorbing |
| Structural Features | Aromatic ring present |
| CAS Registry Year (est.) | 1957 |
| Nitrogen Atoms | 2 |
Related Rivaroxaban Standards
- Rivaroxaban Impurity 112 (CAS 90564-02-6)
- Rivaroxaban Impurity 53 (CAS 66357-41-3)
- Rivaroxaban Impurity 38 (CAS 29518-11-4)
- Rivaroxaban Impurity 103 (CAS 35475-03-7)
- Rivaroxaban CMTCA Impurity (CAS 97799-98-9)
- Rivaroxaban Impurity 137 (CAS 3140-73-6)
- Rivaroxaban Impurity 74 (CAS 113471-08-2)
- Rivaroxaban Impurity 101 (CAS 67482-49-9)
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