Afatinib Impurity 1 CAS 314771-88-5
Purity >95%In StockPharmacopoeial Impurity Standards
| CAS No. | 314771-88-5 |
| Molecular Formula | C18H14ClFN4O4 |
| Molecular Weight | 404.78 g/mol |
| Category | Pharmacopoeial Impurity Standards / EP Impurities |
| Availability | In Stock |
Chemical Structure
Description
Afatinib Impurity 1 (CAS 314771-88-5) reference standard, produced by CATO (ISO 17034 / CNAS / ANAB accredited). Molecular formula: C18H14ClFN4O4. Molecular weight: 404.78 g/mol. Trusted by 10,000+ laboratories worldwide for pharmaceutical analysis and QC.
Physical & Chemical Properties
| Molecular Formula | C18H14ClFN4O4 |
| Molecular Weight | 404.78 g/mol |
| Appearance | Pale yellow to yellow crystalline powder. (slight halide-like odor, low volatility) |
| Purity | >95% |
| Storage | Store in a cool place (≤25°C), protect from light, keep sealed and dry |
| Solubility (reference) | Soluble in DMSO, DMF, methanol |
| Stability | May oxidize slowly on prolonged air exposure; Light-sensitive; avoid direct strong light; Hygroscopic; reseal immediately after opening; Contains ester bond; hydrolyzes under strong alkaline conditions |
| Degree of Unsaturation (DBE) | 13.0 |
| UV Absorption | UV-absorbing |
| Structural Features | Aromatic ring present |
| CAS Registry Year (est.) | 2025 |
| Halogen Content | F/Cl-containing |
| Nitrogen Atoms | 4 |
Related Afatinib Standards
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Recommended Standards
- (R)-N-(3-chloro-4-fluorophenyl)-6-nitro-7-((tetrahydrofuran-3-yl)oxy)quinazolin-4-amine (CAS 402855-07-6)
- 5-Chloro-1-methyl-4-(((perfluorophenyl)thio)methyl)-3-phenyl-1H-pyrazole (CAS 956949-82-9)
- 2-((2-Chloro-5-(trifluoromethyl)phenyl)amino)-2-oxoethyl 2-(methylthio)nicotinate (CAS 479378-61-5)
- Piperacillin impurity 98 (CAS CATO-C4X-173298)
- Relugolix Impurity 171 (CAS CATO-C4X-2429171)
- 6-Iodo-2,4,8-trimethylquinoline (CAS 1935598-72-3)
- 6-((4-Chlorophenyl)amino)-3-methyl-1H-pyrazolo[4,3-d]pyrimidin-7(6H)-one (CAS 86831-75-6)
- (Z)-Octadec-9-en-1-yl (R,Z)-12-hydroxyoctadec-9-enoate (CAS 36781-75-6)
- Tert-butyl n-(dimethyl-1,3-thiazol-5-yl)carbamate (CAS 1376373-18-0)
- Semaglutide impurity 80 (CAS CATO-C4X-222680)
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