4,5-Difluoronaphthalene-1-carboxylic acid, 97% CAS 405196-37-4
| CAS No. | 405196-37-4 |
| Molecular Formula | C11H6F2O2 |
| Molecular Weight | 208.16 g/mol |
| Category | Pharmaceutical Standards / API Standards |
| Availability | In Stock |
Chemical Structure
Description
4,5-Difluoronaphthalene-1-carboxylic acid, 97% (CAS 405196-37-4) is a high-purity analytical reference standard with the molecular formula C11H6F2O2 and a molecular weight of 208.16 g/mol.
The molecular framework of 4,5-Difluoronaphthalene-1-carboxylic acid, 97% (C11H6F2O2) is characterized by a carboxylic acid group, a hydroxyl group, an ether linkage, fluorine substitution, an aromatic ring system. In reversed-phase chromatography, its retention is governed primarily by its high hydrophobicity (logP), which provides a practical basis for HPLC-UV/DAD or LC-MS method development. The presence of an aromatic ring or conjugated system gives the compound characteristic absorption bands in the UV-Vis region, making it well suited to UV or diode-array detection (DAD).
This reference standard is suitable for quantitative analysis on major chromatographic platforms including HPLC, GC, LC-MS/MS, and GC-MS, serving as an external calibration standard or a system suitability test reference material.
CATO manufactures 4,5-Difluoronaphthalene-1-carboxylic acid, 97% under ISO 17034:2016 accreditation with dual CNAS and ANAB accreditation. Each batch is characterized by orthogonal methods and supplied with a full Certificate of Analysis (COA), ensuring metrological traceability.
Physical & Chemical Properties
| Molecular Formula | C11H6F2O2 |
| Molecular Weight | 208.16 g/mol |
| Appearance | Pale yellow to yellow crystalline powder. (slight halide-like odor, low volatility) |
| Purity | 97%+ |
| Storage | Store at 2-8°C, protect from light, keep tightly closed to prevent evaporation |
| Solubility (reference) | Soluble in chloroform, dichloromethane, ethyl acetate, DMSO |
| Stability | May oxidize slowly on prolonged air exposure; Light-sensitive; avoid direct strong light; Contains ester bond; hydrolyzes under strong alkaline conditions |
| Degree of Unsaturation (DBE) | 8.0 |
| UV Absorption | UV-absorbing |
| Structural Features | Aromatic ring present |
| CAS Registry Year (est.) | 2025 |
| Halogen Content | F-containing |
Related Difluoronaphthalene Standards
- 5,7-Difluoronaphthalene-1-carboxylic acid, 97% (CAS 405196-34-1)
- 6,7-Difluoronaphthalene-1-carboxylic acid, 97% (CAS 405196-36-3)
- 1-Acetyl-4,5-difluoronaphthalene, 97% (CAS 405196-53-4)
- 7,8-Difluoronaphthalene-1,3-diol (CAS 2858674-29-8)
- 1,5-Difluoronaphthalene (CAS 315-58-2)
- 1,8-Difluoronaphthalene, 97% (CAS 30389-93-6)
- 2,6-Difluoronaphthalene (CAS 59079-69-5)
Recommended Standards
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- 2-cyano-3-(3,4-difluorophenyl)prop-2-enamide (CAS 387844-19-1)
- 1-[4-(aminomethyl)-2,3,5,6-tetrafluorophenyl]methanamine (CAS 89992-50-7)
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- Methyl ((3S,4S)-1-benzyl-4-methylpiperidin-3-yl)carbamate (CAS 1820579-71-2)
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- 3'-Hydroxy Repaglinide-d5 (Mixture of Diastereomers) (CAS 1352792-15-4)
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Why CATO?
- ISO 17034 accredited reference material producer (CNAS + ANAB dual accreditation)
- 130,000+ catalog items in stock, COA supplied with every batch
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- Technical support: +86 18665070610 / Nicole.chen@cato-chem.com