1-Acetyl-4,5-difluoronaphthalene, 97% CAS 405196-53-4
| CAS No. | 405196-53-4 |
| Molecular Formula | C12H8F2O |
| Molecular Weight | 206.19 g/mol |
| Category | Pharmaceutical Standards / API Standards |
| Availability | In Stock |
Chemical Structure
Description
This reference standard is suitable for quantitative analysis on major chromatographic platforms including HPLC, GC, LC-MS/MS, and GC-MS, serving as an external calibration standard or a system suitability test reference material.
CATO supplies 1-Acetyl-4,5-difluoronaphthalene, 97% (CAS 405196-53-4), a certified reference material (molecular formula C12H8F2O, MW 206.19 g/mol) for analytical method development and quality control.
Structurally, 1-Acetyl-4,5-difluoronaphthalene, 97% (C12H8F2O) contains a hydroxyl group, an ether linkage, fluorine substitution, an aromatic ring system. The molecule exhibits a degree of unsaturation (DBE) of 8.0, corresponding to approximately 8 ring(s) or double-bond equivalent(s). With a molecular weight of 206.19 g/mol, it falls into the medium-molecular-weight range. The high carbon-to-hydrogen ratio imparts good lipophilicity, allowing liquid-liquid extraction with non-polar solvents such as n-hexane or ethyl acetate.
The assigned purity is verified by mass-balance and quantitative NMR (qNMR) approaches, with the expanded uncertainty reported at a 95% confidence level (k=2). Batch homogeneity and stability are independently assessed for every lot.
Physical & Chemical Properties
| Molecular Formula | C12H8F2O |
| Molecular Weight | 206.19 g/mol |
| Purity | 97%+ |
| Storage | Store at 2-8°C, protect from light, keep tightly closed to prevent evaporation |
| Solubility (reference) | Soluble in chloroform, dichloromethane, ethyl acetate, DMSO |
| Stability | May oxidize slowly on prolonged air exposure; Light-sensitive; avoid direct strong light |
| Degree of Unsaturation (DBE) | 8.0 |
| UV Absorption | UV-absorbing |
| Structural Features | Aromatic ring present |
| CAS Registry Year (est.) | 2025 |
| Halogen Content | F-containing |
Related Acetyl Standards
- 4,5-Difluoronaphthalene-1-carboxylic acid, 97% (CAS 405196-37-4)
- 5,7-Difluoronaphthalene-1-carboxylic acid, 97% (CAS 405196-34-1)
- 6,7-Difluoronaphthalene-1-carboxylic acid, 97% (CAS 405196-36-3)
- 7,8-Difluoronaphthalene-1,3-diol (CAS 2858674-29-8)
- 1,5-Difluoronaphthalene (CAS 315-58-2)
- 1,8-Difluoronaphthalene, 97% (CAS 30389-93-6)
- 2,6-Difluoronaphthalene (CAS 59079-69-5)
Recommended Standards
- 1-2-O-Ethylidene β-D-mannopyranose (CAS 230953-16-9)
- 1-Phenylcyclopropane-1,2-dicarboxylic acid (CAS 63162-65-2)
- Diethyl 2,3-dihydroxysuccinate (CAS 408332-88-7)
- 2-((1-Oxo-2,3-dihydro-1H-inden-5-yl)oxy)acetic acid (CAS 28945-98-4)
- 2,5-bis(m-tolylamino)cyclohexa-2,5-diene-1,4-dione (CAS CATO-C3D-262168)
- n-(2-Cyanopropyl)-N-ethylcyclohexanecarboxamide (CAS 1249112-87-5)
- 2-Hydroxy-6-(trifluoromethoxy)benzene-1-sulfonyl chloride (CAS 1261679-48-4)
- Methyl 8-azabicyclo[3.2.1]octane-3-carboxylate hydrochloride (CAS 179022-43-6)
- (2S,3R,4R,5R)-5-(benzyloxymethyl)-4-[tert-butyl(dimethyl)silyl]oxy-3-methoxy-2-phenyl-tetrahydrofuran-2-ol (CAS 1583260-00-7)
- 4-tert-Butylcalix[5]arene (CAS 81475-22-1)
- 4-(Dimethylamino)-1-methylquinolin-2(1H)-one (CAS 947-70-6)
- 2-(3-Cyclopropyl-4-(difluoromethyl)-6-(1,5-dimethyl-1h-pyrazol-4-yl)-1h-pyrazolo[3,4-b]pyridin-1-yl)acetic acid (CAS 1006478-10-9)
- 2-Hydroxy-6-phenylhexanenitrile (CAS 288863-28-5)
- Semaglutide impurity 29 (CAS 1188328-22-4)
Why CATO?
- ISO 17034 accredited reference material producer (CNAS + ANAB dual accreditation)
- 130,000+ catalog items in stock, COA supplied with every batch
- Worldwide shipping with full export documentation (HS code guidance available)
- Technical support: +86 18665070610 / Nicole.chen@cato-chem.com