(Z)-({1-[3-chloro-5-(trifluoromethyl)pyridin-2-yl]-1H-pyrazol-5-yl}methylidene)({2-[3-(trifluoromethyl)phenoxy]ethoxy})amine CAS 318248-54-3
| CAS No. | 318248-54-3 |
| Molecular Formula | C19H13ClF6N4O2 |
| Molecular Weight | 478.78 g/mol |
| Category | Pharmaceutical Standards / API Standards |
| Availability | In Stock |
Chemical Structure
Description
Under current pharmacopoeial and regulatory frameworks, quality-control requirements for this class of reference material explicitly involve the control of targets including (Z)-({1-[3-chloro-5-(trifluoromethyl)pyridin-2-yl]-1H-pyrazol-5-yl}methylidene)({2-[3-(trifluoromethyl)phenoxy]ethoxy})amine.
CATO supplies (Z)-({1-[3-chloro-5-(trifluoromethyl)pyridin-2-yl]-1H-pyrazol-5-yl}methylidene)({2-[3-(trifluoromethyl)phenoxy]ethoxy})amine (CAS 318248-54-3), a certified reference material (molecular formula C19H13ClF6N4O2, MW 478.78 g/mol) for analytical method development and quality control.
Owing to a steroid core, an amide group, a hydroxyl group, an ether linkage, fluorine/chlorine substitution, (Z)-({1-[3-chloro-5-(trifluoromethyl)pyridin-2-yl]-1H-pyrazol-5-yl}methylidene)({2-[3-(trifluoromethyl)phenoxy]ethoxy})amine is typically pale yellow to yellow crystalline powder. Its solid-state physicochemical attributes — including a molecular weight of 478.78 g/mol — guide the selection of appropriate sample preparation and analytical techniques. Nitrogen-containing functional groups confer excellent ionization efficiency in positive-ion electrospray (ESI) mode, making the compound well suited to LC-MS/MS analysis.
This reference standard is suitable for quantitative analysis on major chromatographic platforms including HPLC, GC, LC-MS/MS, and GC-MS, serving as an external calibration standard or a system suitability test reference material.
The assigned purity is verified by mass-balance and quantitative NMR (qNMR) approaches, with the expanded uncertainty reported at a 95% confidence level (k=2). Batch homogeneity and stability are independently assessed for every lot.
Physical & Chemical Properties
| Molecular Formula | C19H13ClF6N4O2 |
| Molecular Weight | 478.78 g/mol |
| Appearance | Pale yellow to yellow crystalline powder. (slight halide-like odor, low volatility) |
| Purity | 97%+ |
| Storage | Store in a cool place (≤25°C), protect from light, keep sealed and dry |
| Solubility (reference) | Soluble in DMSO, DMF, methanol |
| Stability | May oxidize slowly on prolonged air exposure; Light-sensitive; avoid direct strong light; Hygroscopic; reseal immediately after opening; Contains ester bond; hydrolyzes under strong alkaline conditions |
| Degree of Unsaturation (DBE) | 12.0 |
| UV Absorption | UV-absorbing |
| Structural Features | Aromatic ring present |
| CAS Registry Year (est.) | 2025 |
| Halogen Content | F/Cl-containing |
| Nitrogen Atoms | 4 |
Related Z Standards
- 3-[(1E)-1-{2-[3-chloro-5-(trifluoromethyl)pyridin-2-yl]-2-methylhydrazin-1-yl}-2-cyanoeth-1-en-1-yl]-1-[3-(trifluoromethyl)phenyl]urea (CAS 337920-17-9)
- 2-Chloro-7-iodo-9,9-diphenyl-9H-fluorene (CAS 851119-15-8)
- 1-[3-Chloro-5-(trifluoromethyl)pyridin-2-yl]-N'-[(1E)-[3-(trifluoromethyl)phenyl]methylidene]piperidine-4-carbohydrazide (CAS 338761-42-5)
- 3-((2-Chloro-6-fluorobenzyl)thio)-5-(((2,6-dichlorobenzyl)sulfinyl)methyl)-4-methyl-4H-1,2,4-triazole (CAS 344271-85-8)
- 3-{[(2-chloro-6-fluorophenyl)methyl]sulfanyl}-5-{[(2,4-dichlorophenyl)methanesulfinyl]methyl}-4-methyl-4H-1,2,4-triazole (CAS 344272-24-8)
- 2-((3-Chloro-5-(trifluoromethyl)pyridin-2-yl)thio)-N-(2,4-dichlorophenyl)nicotinamide (CAS 338774-95-1)
- (R)-4-[[3-Chloro-4-(3,3,3-trifluoro-2-hydroxy-2-methylpropanamido)phenyl]sulfonyl]-N,N-dimethylbenzamide (CAS 252017-04-2)
- 3-(4-((2-Chloro-6-fluorobenzyl)oxy)phenyl)-1-((2,4-difluorophenyl)sulfonyl)-1H-pyrazole (CAS 477710-96-6)
Recommended Standards
- Alpha-Tocopherol-D6 Acetate (CAS 143731-16-2)
- 1-(3-Chlorobenzyl)-3-(5-((2,4-dichlorobenzyl)thio)-1,3,4-oxadiazol-2-yl)pyridin-2(1H)-one (CAS 477852-94-1)
- 3α-O-tert-Butyldimethylsilyl Tetrahydro Cortisone (CAS 83274-73-1)
- 6-Amino-4-{2-[3-chloro-5-(trifluoromethyl)pyridin-2-yl]-2-methylhydrazin-1-yl}-1-[3-(trifluoromethyl)phenyl]-1,2-dihydropyrimidin-2-one (CAS 338965-02-9)
- 2-(3-(2-(Difluoromethoxy)phenyl)-1,2,4-oxadiazol-5-yl)benzoic acid (CAS 1431729-60-0)
- 5-Chloro-6-propylpyrimidine-2,4(1H,3H)-dione (CAS 89856-75-7)
- Dibenzo[a,c]phenazin-11-amine (CAS 62686-19-5)
- Ethyl 5-(benzyloxy)-2-methylbenzofuran-3-carboxylate (CAS 5010-40-2)
- n-[2-(4-methoxyphenyl)ethyl]-2-methylpyrazolo[1,5-a]quinazolin-5-amine (CAS 874009-94-6)
- 5-(tert-Butoxycarbonylamino)-4,4-difluoro-2-methylpentanoic acid (CAS 1404196-60-6)
- 6-Fluoro-4-methoxyquinoline (CAS 61293-17-2)
- CAS 251459-09-3 (CAS 251459-09-3)
- 3-{5h,6h,7h,8h-[1,2,4]triazolo[4,3-a]pyridin-3-yl}aniline (CAS 1039975-28-4)
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