(E)-({1-[3-chloro-5-(trifluoromethyl)pyridin-2-yl]-1H-pyrazol-5-yl}methylidene)(methoxy)amine CAS 318958-96-2
| CAS No. | 318958-96-2 |
| Molecular Formula | C11H8ClF3N4O |
| Molecular Weight | 304.66 g/mol |
| Category | Pharmaceutical Standards / API Standards |
| Availability | In Stock |
Chemical Structure
Description
Under current pharmacopoeial and regulatory frameworks, quality-control requirements for this class of reference material explicitly involve the control of targets including (E)-({1-[3-chloro-5-(trifluoromethyl)pyridin-2-yl]-1H-pyrazol-5-yl}methylidene)(methoxy)amine.
CATO supplies (E)-({1-[3-chloro-5-(trifluoromethyl)pyridin-2-yl]-1H-pyrazol-5-yl}methylidene)(methoxy)amine (CAS 318958-96-2), a certified reference material (molecular formula C11H8ClF3N4O, MW 304.66 g/mol) for analytical method development and quality control.
The molecular framework of (E)-({1-[3-chloro-5-(trifluoromethyl)pyridin-2-yl]-1H-pyrazol-5-yl}methylidene)(methoxy)amine (C11H8ClF3N4O) is characterized by a nitrogen-containing heterocyclic scaffold, an amide group, a hydroxyl group, an ether linkage, fluorine/chlorine substitution. In reversed-phase chromatography, its retention is governed primarily by the protonation state of its nitrogen-containing groups, which provides a practical basis for HPLC-UV/DAD or LC-MS method development. Halogen substitution (F/Cl/Br/I) produces a distinctive isotope pattern in mass spectrometry, a valuable aid for qualitative confirmation.
This reference standard is suitable for quantitative analysis on major chromatographic platforms including HPLC, GC, LC-MS/MS, and GC-MS, serving as an external calibration standard or a system suitability test reference material.
CATO manufactures (E)-({1-[3-chloro-5-(trifluoromethyl)pyridin-2-yl]-1H-pyrazol-5-yl}methylidene)(methoxy)amine under ISO 17034:2016 accreditation with dual CNAS and ANAB accreditation. Each batch is characterized by orthogonal methods and supplied with a full Certificate of Analysis (COA), ensuring metrological traceability.
Physical & Chemical Properties
| Molecular Formula | C11H8ClF3N4O |
| Molecular Weight | 304.66 g/mol |
| Appearance | Pale yellow to yellow crystalline powder. (slight halide-like odor, low volatility) |
| Purity | 97%+ |
| Storage | Store at 2-8°C, protect from light |
| Solubility (reference) | Soluble in DMSO, DMF, methanol |
| Stability | May oxidize slowly on prolonged air exposure; Light-sensitive; avoid direct strong light |
| Degree of Unsaturation (DBE) | 8.0 |
| UV Absorption | UV-absorbing |
| Structural Features | Aromatic ring present |
| CAS Registry Year (est.) | 2025 |
| Halogen Content | F/Cl-containing |
| Nitrogen Atoms | 4 |
Related E Standards
- {1-[3-chloro-5-(trifluoromethyl)pyridin-2-yl]-1H-pyrrol-2-yl}urea (CAS 338420-71-6)
- 1-Chloro-2-((4-fluorobenzyl)oxy)-4-(trifluoromethyl)benzene (CAS 1443304-48-0)
- 1-Chloro-2-((2-fluorobenzyl)oxy)-4-(trifluoromethyl)benzene (CAS 1443314-35-9)
- 2-Chloro-1-((2-fluorobenzyl)oxy)-4-(trifluoromethyl)benzene (CAS 1443322-26-6)
- 2-Chloro-1-((3-fluorobenzyl)oxy)-4-(trifluoromethyl)benzene (CAS 1443328-50-4)
- 1-Chloro-2-((3-fluorobenzyl)oxy)-4-(trifluoromethyl)benzene (CAS 1443337-08-3)
- 2-Chloro-1-((4-fluorobenzyl)oxy)-4-(trifluoromethyl)benzene (CAS 1443353-67-0)
- Methyl 2-(3-chloro-5-(trifluoromethyl)pyridin-2-yl)-2,2-difluoroethanimidothioate (CAS 1823183-83-0)
Recommended Standards
- 2-(4-Chlorophenyl)-3-(trifluoromethyl)pyrazole-4-carboxylic acid hydrazide (CAS 175137-34-5)
- N-{[3-(4-chlorophenyl)-1,2-oxazol-5-yl]methyl}-2,2,2-trifluoroacetamide (CAS 672951-48-3)
- N-(2-(1H-1,2,4-triazol-1-yl)-5-(trifluoromethyl)phenyl)-2-chloroacetamide (CAS 792953-79-8)
- N-(4-chloro-3-methylisoxazol-5-yl)-3-(trifluoromethyl)benzamide (CAS 478262-53-2)
- N,3-dimethylbenzamide (CAS 74786-81-5)
- 1-ethyl-3-(hydroxyimino)-5-methyl-2,3-dihydro-1H-indol-2-one (CAS 1443987-58-3)
- 2-(2-Bromophenoxy)-n,n-dimethylacetamide (CAS 1016837-70-9)
- (E)-3-Benzylidenedihydrofuran-2,5-dione (CAS 125702-11-6)
- 5-Amino-1-(8-fluoroquinolin-4-yl)-1H-pyrazole-4-carbonitrile (CAS 1221411-06-8)
- tert-Butyl 2-(6-(propylamino)pyridin-3-yl)piperidine-1-carboxylate (CAS 1352530-66-5)
- N1,N1-Bis(furan-2-ylmethyl)adipamide (CAS 61190-71-4)
- 4,4-Difluoro-3,3-dimethylpentanoic acid (CAS 2024430-38-2)
- (R)-1,2-Dihydroacenaphthene-1-amine (CAS 228246-73-9)
- Prolactin-Releasing Peptide (1-31) (rat) (CAS 215510-06-8)
Why CATO?
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