{1-[3-chloro-5-(trifluoromethyl)pyridin-2-yl]-1H-pyrrol-2-yl}urea CAS 338420-71-6
| CAS No. | 338420-71-6 |
| Molecular Formula | C11H8ClF3N4O |
| Molecular Weight | 304.66 g/mol |
| Category | Pharmaceutical Standards / API Standards |
| Availability | In Stock |
Chemical Structure
Description
Under current pharmacopoeial and regulatory frameworks, quality-control requirements for this class of reference material explicitly involve the control of targets including {1-[3-chloro-5-(trifluoromethyl)pyridin-2-yl]-1H-pyrrol-2-yl}urea.
CATO supplies {1-[3-chloro-5-(trifluoromethyl)pyridin-2-yl]-1H-pyrrol-2-yl}urea (CAS 338420-71-6), a certified reference material (molecular formula C11H8ClF3N4O, MW 304.66 g/mol) for analytical method development and quality control.
Structurally, {1-[3-chloro-5-(trifluoromethyl)pyridin-2-yl]-1H-pyrrol-2-yl}urea (C11H8ClF3N4O) contains a nitrogen-containing heterocyclic scaffold, an amide group, a hydroxyl group, an ether linkage, fluorine/chlorine substitution. The molecule exhibits a degree of unsaturation (DBE) of 8.0, corresponding to approximately 8 ring(s) or double-bond equivalent(s). With a molecular weight of 304.66 g/mol, it falls into the moderately-high-molecular-weight range. Halogen substitution (F/Cl/Br/I) produces a distinctive isotope pattern in mass spectrometry, a valuable aid for qualitative confirmation.
Recommended for analytical method development and validation; each product is supplied with a full Certificate of Analysis (COA) ensuring ISO 17034 metrological traceability.
The assigned purity is verified by mass-balance and quantitative NMR (qNMR) approaches, with the expanded uncertainty reported at a 95% confidence level (k=2). Batch homogeneity and stability are independently assessed for every lot.
Physical & Chemical Properties
| Molecular Formula | C11H8ClF3N4O |
| Molecular Weight | 304.66 g/mol |
| Appearance | Pale yellow to yellow crystalline powder. (slight halide-like odor, low volatility) |
| Purity | 97%+ |
| Storage | Store at 2-8°C, protect from light |
| Solubility (reference) | Soluble in DMSO, DMF, methanol |
| Stability | May oxidize slowly on prolonged air exposure; Light-sensitive; avoid direct strong light |
| Degree of Unsaturation (DBE) | 8.0 |
| UV Absorption | UV-absorbing |
| Structural Features | Aromatic ring present |
| CAS Registry Year (est.) | 2025 |
| Halogen Content | F/Cl-containing |
| Nitrogen Atoms | 4 |
Related chloro Standards
- (E)-({1-[3-chloro-5-(trifluoromethyl)pyridin-2-yl]-1H-pyrazol-5-yl}methylidene)(methoxy)amine (CAS 318958-96-2)
- 1-Chloro-2-((4-fluorobenzyl)oxy)-4-(trifluoromethyl)benzene (CAS 1443304-48-0)
- 1-Chloro-2-((2-fluorobenzyl)oxy)-4-(trifluoromethyl)benzene (CAS 1443314-35-9)
- 2-Chloro-1-((2-fluorobenzyl)oxy)-4-(trifluoromethyl)benzene (CAS 1443322-26-6)
- 2-Chloro-1-((3-fluorobenzyl)oxy)-4-(trifluoromethyl)benzene (CAS 1443328-50-4)
- 1-Chloro-2-((3-fluorobenzyl)oxy)-4-(trifluoromethyl)benzene (CAS 1443337-08-3)
- 2-Chloro-1-((4-fluorobenzyl)oxy)-4-(trifluoromethyl)benzene (CAS 1443353-67-0)
- Methyl 2-(3-chloro-5-(trifluoromethyl)pyridin-2-yl)-2,2-difluoroethanimidothioate (CAS 1823183-83-0)
Recommended Standards
- N-(2-(1H-1,2,4-triazol-1-yl)-5-(trifluoromethyl)phenyl)-2-chloroacetamide (CAS 792953-79-8)
- 2-(4-Chlorophenyl)-3-(trifluoromethyl)pyrazole-4-carboxylic acid hydrazide (CAS 175137-34-5)
- Triallate (CAS 2303-17-5)
- N-{[3-(4-chlorophenyl)-1,2-oxazol-5-yl]methyl}-2,2,2-trifluoroacetamide (CAS 672951-48-3)
- 3,4-Dihydro-2H-1,5-benzodioxepine-7-boronic Acid (CAS 279261-89-1)
- 2-(4-Amino-3-nitrophenoxy)ethan-1-ol (CAS 50982-74-6)
- n-(4-Chlorophenyl)-3-oxo-3-phenylpropanamide (CAS 962-08-3)
- Trimebutine Impurity 16 (CAS CATO-C4X-185816)
- (S)-1-(2-Methyl-3-(trifluoromethyl)phenyl)ethan-1-ol (CAS 2359693-77-7)
- Ethyl 4-amino-5-iodo-6-methoxynicotinate (CAS 2883421-53-0)
- 5-Oxo-N-(m-tolyl)tetrahydrofuran-2-carboxamide (CAS 797019-95-5)
- 5-Hydroxymethylsalicylaldehyde (CAS 74901-08-9)
- Dimethyl 2-((tert-butoxycarbonyl)amino)malonate (CAS 61172-70-1)
- D-Ala35-Tirzepatide (CAS CATO-CPTD788904)
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