4-(4-Chlorophenyl)-6-(4-methylpiperazin-1-yl)-2-(pyridin-4-yl)pyrimidine-5-carbonitrile CAS 320418-28-8

Description

This reference standard is suitable for quantitative analysis on major chromatographic platforms including HPLC, GC, LC-MS/MS, and GC-MS, serving as an external calibration standard or a system suitability test reference material.

CATO supplies 4-(4-Chlorophenyl)-6-(4-methylpiperazin-1-yl)-2-(pyridin-4-yl)pyrimidine-5-carbonitrile (CAS 320418-28-8), a certified reference material (molecular formula C21H19ClN6, MW 390.87 g/mol) for analytical method development and quality control.

The molecular framework of 4-(4-Chlorophenyl)-6-(4-methylpiperazin-1-yl)-2-(pyridin-4-yl)pyrimidine-5-carbonitrile (C21H19ClN6) is characterized by a nitrogen-containing heterocyclic scaffold, a nitrile group, chlorine substitution. In reversed-phase chromatography, its retention is governed primarily by the protonation state of its nitrogen-containing groups, which provides a practical basis for HPLC-UV/DAD or LC-MS method development. The aromatic system may exhibit native fluorescence, enabling detection with a fluorescence detector (FLD).

The assigned purity is verified by mass-balance and quantitative NMR (qNMR) approaches, with the expanded uncertainty reported at a 95% confidence level (k=2). Batch homogeneity and stability are independently assessed for every lot.

Physical & Chemical Properties

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