Lubiprostone Impurity 18 CAS 201226-21-3
| CAS No. | 201226-21-3 |
| Molecular Formula | C20H32F2O5 |
| Molecular Weight | 390.46 g/mol |
| Category | Pharmacopoeial Impurity Standards / EP Impurities |
| Availability | In Stock |
Chemical Structure
Description
Compared with other compounds in its class, the molecular weight of 390.46 g/mol gives Lubiprostone Impurity 18 distinctive chromatographic separation conditions and mass-spectrometry parameter settings.
CATO supplies Lubiprostone Impurity 18 (CAS 201226-21-3), a pharmacopoeial impurity reference standard (molecular formula C20H32F2O5, MW 390.46 g/mol) used for the identification and quantification of trace impurities in APIs.
The molecular framework of Lubiprostone Impurity 18 (C20H32F2O5) is characterized by a steroid core, a hydroxyl group, an ether linkage, fluorine substitution. In reversed-phase chromatography, its retention is governed primarily by the polarity and ionization state of its functional groups, which provides a practical basis for HPLC-UV/DAD or LC-MS method development. The aromatic system may exhibit native fluorescence, enabling detection with a fluorescence detector (FLD).
Recommended for quantitative analysis by HPLC, GC, LC-MS/MS, or GC-MS as an external calibration standard; it can also be used for spiked-recovery experiments, LOD/LOQ determination, and LC-MS/MS multiple-reaction-monitoring (MRM) calibration.
CATO manufactures Lubiprostone Impurity 18 under ISO 17034:2016 accreditation with dual CNAS and ANAB accreditation. Each batch is characterized by orthogonal methods and supplied with a full Certificate of Analysis (COA), ensuring metrological traceability.
Physical & Chemical Properties
| Molecular Formula | C20H32F2O5 |
| Molecular Weight | 390.46 g/mol |
| Appearance | Off-white to pale yellow crystalline powder. (slight halide-like odor, low volatility) |
| Purity | >95% |
| Storage | Store at room temperature, keep sealed and dry |
| Solubility (reference) | Soluble in methanol, acetonitrile, DMSO, water (slightly soluble) |
| Stability | May oxidize slowly on prolonged air exposure; Contains ester bond; hydrolyzes under strong alkaline conditions |
| Degree of Unsaturation (DBE) | 4.0 |
| UV Absorption | UV-absorbing |
| Structural Features | Aromatic ring present |
| CAS Registry Year (est.) | 2014 |
| Halogen Content | F-containing |
Related Lubiprostone Standards
- Lubiprostone (CAS 136790-76-6/333963-40-9)
- Lubiprostone Impurity 3 (CAS 1263283-38-0)
- Lubiprostone Impurity 30 (CAS 2743427-14-5)
- Lubiprostone Impurity 31 (CAS CATO-C4X-113631)
- Lubiprostone Impurity 32 (CAS CATO-C4X-113632)
- Lubiprostone Impurity 33 (CAS CATO-C4X-113633)
- Lubiprostone Impurity 35 (CAS 1808535-45-6 (Cyclo Form))
- Lubiprostone Impurity 40 (CAS CATO-C4X-113640)
Recommended Standards
- Sildenafil Impurity 76 (CAS CATO-C4X-112876)
- N-(Benzo[d][1,3]dioxol-5-ylmethyl)-5,6-dimethyl-2-(pyridin-3-yl)thieno[2,3-d]pyrimidin-4-amine (CAS 796052-04-5)
- N-(5-Cyclopropyl-1,3,4-oxadiazol-2-yl)-4-((2-methylpiperidin-1-yl)sulfonyl)benzamide (CAS 850935-88-5)
- N'-(4-Methoxybenzylidene)-3-methyl-1-phenyl-1H-thieno[2,3-c]pyrazole-5-carbohydrazide (CAS 332390-41-7)
- Glycine Impurity 6 (CAS CATO-C4X-33366)
- Exemestane Impurity 19 (CAS CATO-C4X-164119)
- Acalabrutinib Impurity 10 (CAS CATO-C4X-305510)
- Methyl 3-hydroxy-4-methoxy-2-nitrobenzoate (CAS 90564-40-2)
- 1-((5-Bromo-2-methoxyphenyl)sulfonyl)-4-methylpiperazine (CAS 325809-71-0)
- EThyl 3-[(4-nitrophenyl)formamido]propanoate (CAS 172899-47-7)
- 3-(3-Bromo-2-fluorophenyl)propanoic acid (CAS 1261814-91-8)
- 3-Fluoro-5-methyl-2-nitrophenol (CAS 1806475-40-0)
- 6-Ethoxynaphthalen-1-amine (CAS 837428-13-4)
- Neuroendocrine Regulatory Peptide-4 (human, mouse, rat) (H-7266.1000) (CAS 922704-18-5)
Why CATO?
- ISO 17034 accredited reference material producer (CNAS + ANAB dual accreditation)
- 130,000+ catalog items in stock, COA supplied with every batch
- Worldwide shipping with full export documentation (HS code guidance available)
- Technical support: +86 18665070610 / Nicole.chen@cato-chem.com