5-chloro-1-[(3,4-dichlorophenyl)methyl]-1H-Indole-2,3-dione-3-[O-(4-chloro-1-oxobutyl)oxime] CAS 320420-78-8
| CAS No. | 320420-78-8 |
| Molecular Formula | C19H14Cl4N2O3 |
| Molecular Weight | 460.14 g/mol |
| Category | Pharmaceutical Standards / API Standards |
| Availability | In Stock |
Chemical Structure
Description
Under current pharmacopoeial and regulatory frameworks, quality-control requirements for this class of reference material explicitly involve the control of targets including 5-chloro-1-[(3,4-dichlorophenyl)methyl]-1H-Indole-2,3-dione-3-[O-(4-chloro-1-oxobutyl)oxime].
CATO supplies 5-chloro-1-[(3,4-dichlorophenyl)methyl]-1H-Indole-2,3-dione-3-[O-(4-chloro-1-oxobutyl)oxime] (CAS 320420-78-8), a certified reference material (molecular formula C19H14Cl4N2O3, MW 460.14 g/mol) for analytical method development and quality control.
Owing to a steroid core, an amide group, a hydroxyl group, an ether linkage, chlorine substitution, 5-chloro-1-[(3,4-dichlorophenyl)methyl]-1H-Indole-2,3-dione-3-[O-(4-chloro-1-oxobutyl)oxime] is typically pale yellow to yellow crystalline powder. Its solid-state physicochemical attributes — including a molecular weight of 460.14 g/mol — guide the selection of appropriate sample preparation and analytical techniques. The aromatic system may exhibit native fluorescence, enabling detection with a fluorescence detector (FLD).
This reference standard is suitable for quantitative analysis on major chromatographic platforms including HPLC, GC, LC-MS/MS, and GC-MS, serving as an external calibration standard or a system suitability test reference material.
The assigned purity is verified by mass-balance and quantitative NMR (qNMR) approaches, with the expanded uncertainty reported at a 95% confidence level (k=2). Batch homogeneity and stability are independently assessed for every lot.
Physical & Chemical Properties
| Molecular Formula | C19H14Cl4N2O3 |
| Molecular Weight | 460.14 g/mol |
| Appearance | Pale yellow to yellow crystalline powder. (slight halide-like odor, low volatility) |
| Purity | 97%+ |
| Storage | Store in a cool place (≤25°C), protect from light, keep sealed and dry |
| Solubility (reference) | Soluble in DMSO, DMF, methanol |
| Stability | May oxidize slowly on prolonged air exposure; Light-sensitive; avoid direct strong light; Hygroscopic; reseal immediately after opening; Contains ester bond; hydrolyzes under strong alkaline conditions |
| Degree of Unsaturation (DBE) | 12.0 |
| UV Absorption | UV-absorbing |
| Structural Features | Aromatic ring present |
| CAS Registry Year (est.) | 2025 |
| Halogen Content | Cl-containing |
| Nitrogen Atoms | 2 |
Related chloro Standards
- (Z)-5-chloro-3-(((4-chlorobutanoyl)oxy)imino)-1-(2,6-dichlorobenzyl)indolin-2-one (CAS 321430-08-4)
- (2-Chloro-4-Fluorophenyl)Phenylmethanone (CAS 69943-47-1)
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Recommended Standards
- Tris(2,2,3,3,3-pentafluoropropoxy)methane (CAS 917379-07-8)
- N-(5,7-Dibromoquinolin-8-yl)-4-fluorobenzenesulfonamide (CAS 879015-61-9)
- 3-[(3R,4R)-6-Bromo-3-(hydroxymethyl)-3,4-dihydro-2H-1-benzopyran-4-yl]-1-(2,4-dichlorophenyl)-3-methylurea (CAS 324009-22-5)
- 3-(3,5-Dibromo-4-hydroxyphenyl)-3-phenylisobenzofuran-1(3H)-one (CAS 6315-70-4)
- 5-(Pyridin-2-yl)thiophene-2-sulfonamide (CAS 190659-63-3)
- 1-Benzyl-5-Cbz-octahydropyrrolo[3,4-b]pyrrole (CAS 2006278-25-5)
- 4-n-Butylphenol-2,3,5,6-d4,OD (CAS 1219795-04-6)
- 3-Bromo-2-chloro-4-methyl-5-nitropyridine (CAS 1049706-73-1)
- (2-Chloro-5-methoxyphenyl)hydrazine (CAS 69833-19-8)
- Ethyl 2-bromo-6-cyano-4-hydroxybenzoate (CAS 1805191-02-9)
- (E)-2-((4-(dimethylamino)benzylidene)amino)-5-phenylfuran-3-carbonitrile (CAS 478033-31-7)
- 4-Methylquinoline-5-carbaldehyde (CAS 1934480-52-0)
- 4-(Thiazol-2-yl)benzaldehyde (CAS 198904-53-9)
- Insulin Degludec Impurity 24 (CAS CATO-C4X-215724)
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