3-(2-Chlorophenyl)-5-[(E)-2-[(4-fluorophenyl)amino]ethenyl]-1,2-oxazole-4-carbonitrile CAS 320425-16-9
| CAS No. | 320425-16-9 |
| Molecular Formula | C18H11ClFN3O |
| Molecular Weight | 339.75 g/mol |
| Category | Pharmaceutical Standards / API Standards |
| Availability | In Stock |
Chemical Structure
Description
CATO supplies 3-(2-Chlorophenyl)-5-[(E)-2-[(4-fluorophenyl)amino]ethenyl]-1,2-oxazole-4-carbonitrile (CAS 320425-16-9), a certified reference material (molecular formula C18H11ClFN3O, MW 339.75 g/mol) for analytical method development and quality control.
The molecular framework of 3-(2-Chlorophenyl)-5-[(E)-2-[(4-fluorophenyl)amino]ethenyl]-1,2-oxazole-4-carbonitrile (C18H11ClFN3O) is characterized by a steroid core, an amide group, a hydroxyl group, an ether linkage, fluorine/chlorine substitution. In reversed-phase chromatography, its retention is governed primarily by its high hydrophobicity (logP), which provides a practical basis for HPLC-UV/DAD or LC-MS method development. The presence of an aromatic ring or conjugated system gives the compound characteristic absorption bands in the UV-Vis region, making it well suited to UV or diode-array detection (DAD).
Recommended for analytical method development and validation; each product is supplied with a full Certificate of Analysis (COA) ensuring ISO 17034 metrological traceability.
The assigned purity is verified by mass-balance and quantitative NMR (qNMR) approaches, with the expanded uncertainty reported at a 95% confidence level (k=2). Batch homogeneity and stability are independently assessed for every lot.
Physical & Chemical Properties
| Molecular Formula | C18H11ClFN3O |
| Molecular Weight | 339.75 g/mol |
| Appearance | Pale yellow to yellow crystalline powder. (slight halide-like odor, low volatility) |
| Purity | 97%+ |
| Storage | Store at 2-8°C, protect from light |
| Solubility (reference) | Soluble in DMSO, DMF, methanol |
| Stability | May oxidize slowly on prolonged air exposure; Light-sensitive; avoid direct strong light |
| Degree of Unsaturation (DBE) | 14.0 |
| UV Absorption | UV-absorbing |
| Structural Features | Aromatic ring present |
| CAS Registry Year (est.) | 2025 |
| Halogen Content | F/Cl-containing |
| Nitrogen Atoms | 3 |
Related Chlorophenyl Standards
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Recommended Standards
- 3-(2-Chloro-6-fluorophenyl)-5-[(E)-2-(phenylamino)ethenyl]-1,2-oxazole-4-carbonitrile (CAS 338403-14-8)
- Chlorthalidone impurity 19 (CAS CATO-C4X-158519)
- 2-[2-Chloro-4-(hydroxymethyl)-6-methoxyphenoxy]-N-(4-fluorophenyl)acetamide (CAS 693816-01-2)
- Chlortalidone EP Impurity B (CAS 5270-74-6)
- N-(4-(4-Chlorophenyl)-3-((tetrahydrofuran-2-yl)methyl)thiazol-2(3H)-ylidene)aniline (CAS 374096-46-5)
- 2-(1H-Benzo[d]imidazol-2(3H)-ylidene)malononitrile (CAS 4933-40-8)
- (1R,5S,6r)-rel-6-Amino-3-oxabicyclo[3.1.0]hexane Hydrochloride (CAS 1048962-49-7)
- 2',3',4',5',6'-Pentafluoro[1,1'-biphenyl]-4-ylamine (CAS 25506-49-4)
- 3-Chloro-2-{2-phenyl-2H,4H,5H,6H,7H-pyrazolo[4,3-c]pyridin-5-yl}-5-(trifluoromethyl)pyridine (CAS 337919-61-6)
- 1-Bromo-3-chloro-4-methoxy-2-nitrobenzene (CAS 1881321-54-5)
- N-[(4Z)-3-Ethyl-2-oxo-1,2,3,4-tetrahydroquinazolin-4-ylidene]-2-methylpropanamide (CAS 478033-08-8)
- 1-Acetyl-3,3-dimethyl-2,3-dihydro-1H-indole-6-sulfonyl chloride (CAS 1316066-05-3)
- Chlorsulfuron-5-hydroxy (CAS 81123-38-8)
- Insulin Degludec Impurity 24 (CAS CATO-C4X-215724)
Why CATO?
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