N-(3,5-dichlorophenyl)-4-methyl-2-(3-(trifluoromethyl)phenyl)thiazole-5-carboxamide CAS 321429-63-4
| CAS No. | 321429-63-4 |
| Molecular Formula | C18H11Cl2F3N2OS |
| Molecular Weight | 431.26 g/mol |
| Category | Pharmaceutical Standards / API Standards |
| Availability | In Stock |
Chemical Structure
Description
Compared with other compounds in its class, the molecular weight of 431.26 g/mol gives N-(3,5-dichlorophenyl)-4-methyl-2-(3-(trifluoromethyl)phenyl)thiazole-5-carboxamide distinctive chromatographic separation conditions and mass-spectrometry parameter settings.
N-(3,5-dichlorophenyl)-4-methyl-2-(3-(trifluoromethyl)phenyl)thiazole-5-carboxamide (CAS 321429-63-4), molecular formula C18H11Cl2F3N2OS and molecular weight 431.26 g/mol, is a CATO reference standard with documented purity and traceability.
N-(3,5-dichlorophenyl)-4-methyl-2-(3-(trifluoromethyl)phenyl)thiazole-5-carboxamide (C18H11Cl2F3N2OS) contains a steroid core, an amide group, sulfur-containing functionality, a hydroxyl group, an ether linkage, fluorine/chlorine substitution. Halogen substitution raises its density and boiling point, its high carbon-to-hydrogen ratio confers good lipid solubility; these physicochemical properties determine the optimal preparation and storage of its standard solutions. Nitrogen-containing functional groups confer excellent ionization efficiency in positive-ion electrospray (ESI) mode, making the compound well suited to LC-MS/MS analysis.
This reference standard is suitable for quantitative analysis on major chromatographic platforms including HPLC, GC, LC-MS/MS, and GC-MS, serving as an external calibration standard or a system suitability test reference material.
As a certified reference material (CRM), N-(3,5-dichlorophenyl)-4-methyl-2-(3-(trifluoromethyl)phenyl)thiazole-5-carboxamide meets the metrological traceability requirements of ISO/IEC 17025 laboratories. Batch-to-batch consistency is monitored via control charts to guarantee comparable assigned values across lots.
Physical & Chemical Properties
| Molecular Formula | C18H11Cl2F3N2OS |
| Molecular Weight | 431.26 g/mol |
| Purity | 97%+ |
| Storage | Store at room temperature, protect from light |
| Solubility (reference) | Soluble in DMSO, DMF, methanol |
| Stability | May oxidize slowly on prolonged air exposure; Light-sensitive; avoid direct strong light |
| Degree of Unsaturation (DBE) | 12.0 |
| UV Absorption | UV-absorbing |
| Structural Features | Aromatic ring present |
| CAS Registry Year (est.) | 2025 |
| Halogen Content | F/Cl-containing |
| Nitrogen Atoms | 2 |
| Sulfur Atoms | 1 |
Related N Standards
- 2-{[(3,4-dichlorophenyl)methyl]sulfanyl}-3-phenyl-6-(trifluoromethyl)-3,4-dihydropyrimidin-4-one (CAS 692287-47-1)
- N-(2,4-dichlorophenyl)-2-(3-(trifluoromethyl)benzyl)thiazole-4-carboxamide (CAS 478042-44-3)
- N-(2,5-dichlorophenyl)-2-(3-(trifluoromethyl)benzyl)thiazole-4-carboxamide (CAS 478042-53-4)
- N-(3,4-dichlorophenyl)-2-(3-(trifluoromethyl)benzyl)thiazole-4-carboxamide (CAS 478042-45-4)
- N-(3,5-Dichlorophenyl)-2-{[3-(trifluoromethyl)phenyl]methyl}-1,3-thiazole-4-carboxamide (CAS 478030-73-8)
- Methyl 2-{1-[(2,4-dichlorophenyl)methyl]-2-oxo-1,2-dihydropyridine-3-amido}benzoate (CAS 338977-61-0)
- N-(5-(1-(2,6-Dichlorophenyl)-3-(difluoromethyl)-1H-pyrazol-5-yl)thiazol-2-yl)isobutyramide (CAS 1338247-35-0)
- (1-(3,4-Dichlorophenyl)-1H-1,2,3-triazol-4-yl)methyl (3-(trifluoromethyl)phenyl)carbamate (CAS 400081-85-8)
Recommended Standards
- (S)-1-(tert-Butoxycarbonyl)-2-(4-iodobenzyl)pyrrolidine-2-carboxylic acid (CAS 1217686-40-2)
- 1-Benzyl-3-(benzyloxy)-5-iodo-2-methylpyridin-4(1H)-one (CAS 1221792-03-5)
- (2S,4R)-1-(tert-Butoxycarbonyl)-4-(2-iodobenzyl)pyrrolidine-2-carboxylic acid (CAS 959573-29-6)
- (2S,4R)-1-(tert-Butoxycarbonyl)-4-(3-iodobenzyl)pyrrolidine-2-carboxylic acid (CAS 959580-93-9)
- 3-(5-Nitrofuran-2-yl)imidazo[1,2-a]pyridine (CAS 75198-31-1)
- Methyl ((3-aminocyclobutyl)methyl)carbamate (CAS 1468919-07-4)
- 4-Cyclopropoxy-3-ethylbenzaldehyde (CAS 1243344-41-3)
- (5-Cyclohexyl-2-fluorophenyl)boronic acid (CAS 2225175-07-3)
- 2-(3-(Trifluoromethyl)phenyl)cyclopropanecarboxamide (CAS 1374509-36-0)
- 2-(4-Amino-5-(difluoromethyl)-2-(trifluoromethyl)pyridin-3-yl)acetic acid (CAS 1806033-18-0)
- Oseltamivir Impurity 189 (CAS CATO-C4X-1720189)
- 5-Chloro-2-[(4-methylpiperazin-1-yl)methyl]phenol dihydrochloride (CAS 1881289-09-3)
- Liraglutide Impurity 16 TFA Salt (CAS CATO-C4X-199216)
- Liraglutide(5-31)TFA Salt (CAS CATO-C4X-19924)
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