N-(2,5-dichlorophenyl)-2-(3-(trifluoromethyl)benzyl)thiazole-4-carboxamide CAS 478042-53-4
| CAS No. | 478042-53-4 |
| Molecular Formula | C18H11Cl2F3N2OS |
| Molecular Weight | 431.26 g/mol |
| Category | Pharmaceutical Standards / API Standards |
| Availability | In Stock |
Chemical Structure
Description
CATO supplies N-(2,5-dichlorophenyl)-2-(3-(trifluoromethyl)benzyl)thiazole-4-carboxamide (CAS 478042-53-4), a certified reference material (molecular formula C18H11Cl2F3N2OS, MW 431.26 g/mol) for analytical method development and quality control.
The molecular framework of N-(2,5-dichlorophenyl)-2-(3-(trifluoromethyl)benzyl)thiazole-4-carboxamide (C18H11Cl2F3N2OS) is characterized by a steroid core, an amide group, sulfur-containing functionality, a hydroxyl group, an ether linkage, fluorine/chlorine substitution. In reversed-phase chromatography, its retention is governed primarily by its high hydrophobicity (logP), which provides a practical basis for HPLC-UV/DAD or LC-MS method development. Halogen substitution (F/Cl/Br/I) produces a distinctive isotope pattern in mass spectrometry, a valuable aid for qualitative confirmation.
Recommended for analytical method development and validation; each product is supplied with a full Certificate of Analysis (COA) ensuring ISO 17034 metrological traceability.
The assigned purity is verified by mass-balance and quantitative NMR (qNMR) approaches, with the expanded uncertainty reported at a 95% confidence level (k=2). Batch homogeneity and stability are independently assessed for every lot.
Physical & Chemical Properties
| Molecular Formula | C18H11Cl2F3N2OS |
| Molecular Weight | 431.26 g/mol |
| Purity | 97%+ |
| Storage | Store at room temperature, protect from light |
| Solubility (reference) | Soluble in DMSO, DMF, methanol |
| Stability | May oxidize slowly on prolonged air exposure; Light-sensitive; avoid direct strong light |
| Degree of Unsaturation (DBE) | 12.0 |
| UV Absorption | UV-absorbing |
| Structural Features | Aromatic ring present |
| CAS Registry Year (est.) | 2025 |
| Halogen Content | F/Cl-containing |
| Nitrogen Atoms | 2 |
| Sulfur Atoms | 1 |
Related N Standards
- 2-{[(3,4-dichlorophenyl)methyl]sulfanyl}-3-phenyl-6-(trifluoromethyl)-3,4-dihydropyrimidin-4-one (CAS 692287-47-1)
- N-(2,4-dichlorophenyl)-2-(3-(trifluoromethyl)benzyl)thiazole-4-carboxamide (CAS 478042-44-3)
- N-(3,4-dichlorophenyl)-2-(3-(trifluoromethyl)benzyl)thiazole-4-carboxamide (CAS 478042-45-4)
- N-(3,5-Dichlorophenyl)-2-{[3-(trifluoromethyl)phenyl]methyl}-1,3-thiazole-4-carboxamide (CAS 478030-73-8)
- N-(3,5-dichlorophenyl)-4-methyl-2-(3-(trifluoromethyl)phenyl)thiazole-5-carboxamide (CAS 321429-63-4)
- Methyl 2-{1-[(2,4-dichlorophenyl)methyl]-2-oxo-1,2-dihydropyridine-3-amido}benzoate (CAS 338977-61-0)
- N-(5-(1-(2,6-Dichlorophenyl)-3-(difluoromethyl)-1H-pyrazol-5-yl)thiazol-2-yl)isobutyramide (CAS 1338247-35-0)
- (1-(3,4-Dichlorophenyl)-1H-1,2,3-triazol-4-yl)methyl (3-(trifluoromethyl)phenyl)carbamate (CAS 400081-85-8)
Recommended Standards
- [SP-4-2-(1R-trans)]-(1,2-Cyclohexanediamine-N,N’) Dinitratoplatinum(II)DISCONTINUED See C989255 (CAS 66900-68-3)
- Methyl N-(4-iodophenyl)-N-(phenylsulfonyl)glycinate (CAS 678156-66-6)
- (S)-1-(tert-Butoxycarbonyl)-2-(4-iodobenzyl)pyrrolidine-2-carboxylic acid (CAS 1217686-40-2)
- Fmoc-4-Borono-L-Phenylalanine (CAS 273221-71-9)
- 5-(((4-Chlorophenyl)thio)methyl)-N-hydroxyisoxazole-3-carboxamide (CAS 823220-04-8)
- 2,2,2-Trifluoro-1-(5-methyl-3-(trifluoromethyl)-1H-pyrazol-1-yl)ethanone (CAS 261778-40-9)
- 3-chloro-1H-pyrazolo[4,3-b]pyridine-6-carboxylic acid (CAS 1403746-62-2)
- (3S,4R)-4-Methoxy-N-methylpyrrolidin-3-amine (CAS 771441-59-9)
- Pyrene-1,6-dicarbaldehyde (CAS 252338-01-5)
- Bumetanide Impurity 12 (CAS 22893-29-4)
- 4-Iodo-2-trifluoromethylbenzoic acid (CAS 954815-11-3)
- 6-Chloro-5-fluoro-1H-pyrrolo[2,3-b]pyridin-2(3H)-one (CAS 1190322-06-5)
- 2,3,4,6-Tetra(9H-carbazol-9-yl)-5-fluorobenzonitrile (CAS 1819362-10-1)
- 3AEEA-Semaglutide(Endo-AEEA-Semaglutide) (CAS CATO-C4X-2226265)
Why CATO?
- ISO 17034 accredited reference material producer (CNAS + ANAB dual accreditation)
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