Methyl 2-amino-6-(3-chloro-5-(trifluoromethyl)pyridin-2-yl)-4,5,6,7-tetrahydrothieno[2,3-c]pyridine-3-carboxylate CAS 321430-29-9
| CAS No. | 321430-29-9 |
| Molecular Formula | C15H13ClF3N3O2S |
| Molecular Weight | 391.80 g/mol |
| Category | Pharmaceutical Standards / API Standards |
| Availability | In Stock |
Chemical Structure
Description
This reference standard is suitable for quantitative analysis on major chromatographic platforms including HPLC, GC, LC-MS/MS, and GC-MS, serving as an external calibration standard or a system suitability test reference material.
Methyl 2-amino-6-(3-chloro-5-(trifluoromethyl)pyridin-2-yl)-4,5,6,7-tetrahydrothieno[2,3-c]pyridine-3-carboxylate (CAS 321430-29-9), molecular formula C15H13ClF3N3O2S and molecular weight 391.80 g/mol, is a CATO reference standard with documented purity and traceability.
The molecular framework of Methyl 2-amino-6-(3-chloro-5-(trifluoromethyl)pyridin-2-yl)-4,5,6,7-tetrahydrothieno[2,3-c]pyridine-3-carboxylate (C15H13ClF3N3O2S) is characterized by a nitrogen-containing heterocyclic scaffold, an amide group, a sulfone group, a hydroxyl group, an ether linkage, fluorine/chlorine substitution. In reversed-phase chromatography, its retention is governed primarily by the protonation state of its nitrogen-containing groups, which provides a practical basis for HPLC-UV/DAD or LC-MS method development. The aromatic system may exhibit native fluorescence, enabling detection with a fluorescence detector (FLD).
As a certified reference material (CRM), Methyl 2-amino-6-(3-chloro-5-(trifluoromethyl)pyridin-2-yl)-4,5,6,7-tetrahydrothieno[2,3-c]pyridine-3-carboxylate meets the metrological traceability requirements of ISO/IEC 17025 laboratories. Batch-to-batch consistency is monitored via control charts to guarantee comparable assigned values across lots.
Physical & Chemical Properties
| Molecular Formula | C15H13ClF3N3O2S |
| Molecular Weight | 391.80 g/mol |
| Purity | 97%+ |
| Storage | Store at 2-8°C, protect from light, keep sealed and dry |
| Solubility (reference) | Soluble in DMSO, DMF, methanol |
| Stability | May oxidize slowly on prolonged air exposure; Light-sensitive; avoid direct strong light; Hygroscopic; reseal immediately after opening; Contains ester bond; hydrolyzes under strong alkaline conditions |
| Degree of Unsaturation (DBE) | 9.0 |
| UV Absorption | UV-absorbing |
| Structural Features | Aromatic ring present |
| CAS Registry Year (est.) | 2025 |
| Halogen Content | F/Cl-containing |
| Nitrogen Atoms | 3 |
| Sulfur Atoms | 1 |
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Recommended Standards
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- 2-[4-Chloro-3-(trifluoromethyl)benzenesulfonamido]-4-(methylsulfanyl)butanoic acid (CAS 1009232-49-8)
- 4-Chloro-6-(chloromethyl)picolinonitrile (CAS 1393560-94-5)
- Methyl 4-amino-3-(benzyloxy)-5-bromobenzoate (CAS 881909-58-6)
- 3-Bromoquinoline-2,5-diol (CAS 1192263-85-6)
- (R)-4-acetyl-1-((S)-1-(4-methoxyphenyl)ethyl)pyrrolidin-2-one (CAS 1319738-36-7)
- N,N-Diethyl-2,4-dimethyloxazol-5-amine (CAS 62026-80-6)
- 3-(Bromomethyl)-2,4,10-trioxatricyclo[3.3.1.13,7]decane (CAS 157371-80-7)
- Pioglitazone EP Impurity G (CAS 952187-99-4)
- 4-[5-Bromo-4-(morpholin-4-yl)pyrimidin-2-yl]morpholine (CAS 1021268-12-1)
- 2-(4-Fluorophenyl)piperidine-1-carbaldehyde (CAS 1355173-54-4)
- Semaglutide Impurity 138 (CAS CATO-C4X-2226138)
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