1-[3-Chloro-5-(trifluoromethyl)pyridin-2-yl]piperidin-4-yl acetate CAS 321430-31-3
| CAS No. | 321430-31-3 |
| Molecular Formula | C13H14ClF3N2O2 |
| Molecular Weight | 322.71 g/mol |
| Category | Pharmaceutical Standards / API Standards |
| Availability | In Stock |
Chemical Structure
Description
1-[3-Chloro-5-(trifluoromethyl)pyridin-2-yl]piperidin-4-yl acetate (C13H14ClF3N2O2) contains a nitrogen-containing heterocyclic scaffold, an amide group, a hydroxyl group, an ether linkage, fluorine/chlorine substitution. It is notably hygroscopic, halogen substitution raises its density and boiling point, its high carbon-to-hydrogen ratio confers good lipid solubility, the carboxyl group imparts weak acidity; these physicochemical properties determine the optimal preparation and storage of its standard solutions. The aromatic system may exhibit native fluorescence, enabling detection with a fluorescence detector (FLD).
1-[3-Chloro-5-(trifluoromethyl)pyridin-2-yl]piperidin-4-yl acetate (CAS 321430-31-3) is a high-purity analytical reference standard with the molecular formula C13H14ClF3N2O2 and a molecular weight of 322.71 g/mol.
Recommended for analytical method development and validation; each product is supplied with a full Certificate of Analysis (COA) ensuring ISO 17034 metrological traceability.
CATO manufactures 1-[3-Chloro-5-(trifluoromethyl)pyridin-2-yl]piperidin-4-yl acetate under ISO 17034:2016 accreditation with dual CNAS and ANAB accreditation. Each batch is characterized by orthogonal methods and supplied with a full Certificate of Analysis (COA), ensuring metrological traceability.
Physical & Chemical Properties
| Molecular Formula | C13H14ClF3N2O2 |
| Molecular Weight | 322.71 g/mol |
| Appearance | Off-white to pale yellow crystalline powder. (slight halide-like odor, low volatility) |
| Purity | 97%+ |
| Storage | Store at 2-8°C, protect from light, keep sealed and dry |
| Solubility (reference) | Soluble in DMSO, DMF, methanol |
| Stability | May oxidize slowly on prolonged air exposure; Light-sensitive; avoid direct strong light; Hygroscopic; reseal immediately after opening; Contains ester bond; hydrolyzes under strong alkaline conditions |
| Degree of Unsaturation (DBE) | 6.0 |
| UV Absorption | UV-absorbing |
| Structural Features | Aromatic ring present |
| CAS Registry Year (est.) | 2025 |
| Halogen Content | F/Cl-containing |
| Nitrogen Atoms | 2 |
Related Chloro Standards
- 6-Chloro-4-trifluoromethyl-3,4,5,6-tetrahydro-2H-[1,2]bipyridinyl-4-carboxylic acid hydrazide (CAS 1208081-12-2)
- 1-(3-Chloro-5-(trifluoromethyl)pyridin-2-yl)-N-hydroxypiperidine-4-carboximidamide (CAS 1221794-66-6)
- 4-Chloro-2-(difluoro(4-fluorophenyl)methyl)-7-methylquinazoline (CAS 1241915-17-2)
- 1-((3-Chloro-5-(trifluoromethyl)pyridin-2-yl)methyl)piperidine-4-carboxylic acid (CAS 1311279-30-7)
- 1-(3-Chloro-5-(trifluoromethyl)pyridin-2-yl)piperidine-4-carbohydrazide (CAS 321430-54-0)
- 1-[5-Chloro-2-nitro-4-(trifluoromethyl)phenyl]azepane (CAS 646456-34-0)
- 2-(3-Chloro-5-(trifluoromethyl)pyridin-2-yl)-N-((tetrahydrofuran-2-yl)methyl)acetamide (CAS 383148-43-4)
- 2-Chloro-n-[2-(morpholin-4-yl)-5-(trifluoromethyl)phenyl]acetamide (CAS 379255-35-3)
Recommended Standards
- 1-(3-Chlorophenyl)-4-(3-(trifluoromethyl)phenyl)-1H-pyrazole (CAS 318288-92-5)
- (2Z)-2-(4-Chlorophenyl)-3-{[3-(trifluoromethyl)phenyl]amino}prop-2-enenitrile (CAS 338403-10-4)
- Ethyl (2S,5S)-5-(5-chloro-2-(trifluoromethyl)pyridin-4-yl)pyrrolidine-2-carboxylate (CAS 1648890-21-4)
- 3-(3-Chloro-5-(trifluoromethyl)pyridin-2-yl)-4-methylquinoline (CAS 882747-53-7)
- 3-Amino-4-methylbenzisoxazole (CAS 1126636-46-1)
- 2-(4-Ethylphenyl)-1H-indole-3-carbaldehyde (CAS 590391-03-0)
- FRAX 486 (CAS 1232030-35-1)
- (5-Methyl-4,5-dihydro-thiazol-2-yl)-phenethyl-amine (CAS 355156-11-5)
- 2-Methylfuran-3-ol (CAS 528825-07-2)
- Methyl 4-acetamido-2-(2-bromoethoxy)-5-chlorobenzoate (CAS 748788-41-2)
- 3-(3-(Ethylsulfonyl)-1H-pyrrol-2-yl)aniline (CAS 1708445-62-8)
- 3-(2-chloroacetyl)bicyclo[1.1.1]pentane-1-carbonitrile (CAS 2573212-73-2)
- [(3-Methylthiophen-2-yl)methyl](propan-2-yl)amine (CAS 937667-47-5)
- Liraglutide (CAS 204656-20-2)
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