1-(4-Chloro-2-fluorophenyl)-3-{[3-chloro-5-(trifluoromethyl)pyridin-2-yl]sulfanyl}pyrrolidine-2,5-dione CAS 321430-90-4
| CAS No. | 321430-90-4 |
| Molecular Formula | C16H8Cl2F4N2O2S |
| Molecular Weight | 439.21 g/mol |
| Category | Pharmaceutical Standards / API Standards |
| Availability | In Stock |
Chemical Structure
Description
As a certified reference material (CRM), 1-(4-Chloro-2-fluorophenyl)-3-{[3-chloro-5-(trifluoromethyl)pyridin-2-yl]sulfanyl}pyrrolidine-2,5-dione meets the metrological traceability requirements of ISO/IEC 17025 laboratories. Batch-to-batch consistency is monitored via control charts to guarantee comparable assigned values across lots.
CATO supplies 1-(4-Chloro-2-fluorophenyl)-3-{[3-chloro-5-(trifluoromethyl)pyridin-2-yl]sulfanyl}pyrrolidine-2,5-dione (CAS 321430-90-4), a certified reference material (molecular formula C16H8Cl2F4N2O2S, MW 439.21 g/mol) for analytical method development and quality control.
1-(4-Chloro-2-fluorophenyl)-3-{[3-chloro-5-(trifluoromethyl)pyridin-2-yl]sulfanyl}pyrrolidine-2,5-dione (C16H8Cl2F4N2O2S) contains a nitrogen-containing heterocyclic scaffold, an amide group, a sulfone group, a hydroxyl group, an ether linkage, fluorine/chlorine substitution. It is notably hygroscopic, halogen substitution raises its density and boiling point, its high carbon-to-hydrogen ratio confers good lipid solubility, the carboxyl group imparts weak acidity; these physicochemical properties determine the optimal preparation and storage of its standard solutions. Nitrogen-containing functional groups confer excellent ionization efficiency in positive-ion electrospray (ESI) mode, making the compound well suited to LC-MS/MS analysis.
This reference standard is suitable for quantitative analysis on major chromatographic platforms including HPLC, GC, LC-MS/MS, and GC-MS, serving as an external calibration standard or a system suitability test reference material.
Physical & Chemical Properties
| Molecular Formula | C16H8Cl2F4N2O2S |
| Molecular Weight | 439.21 g/mol |
| Purity | 97%+ |
| Storage | Store in a cool place (≤25°C), protect from light, keep sealed and dry |
| Solubility (reference) | Soluble in DMSO, DMF, methanol |
| Stability | May oxidize slowly on prolonged air exposure; Light-sensitive; avoid direct strong light; Hygroscopic; reseal immediately after opening; Contains ester bond; hydrolyzes under strong alkaline conditions |
| Degree of Unsaturation (DBE) | 11.0 |
| UV Absorption | UV-absorbing |
| Structural Features | Aromatic ring present |
| CAS Registry Year (est.) | 2025 |
| Halogen Content | F/Cl-containing |
| Nitrogen Atoms | 2 |
| Sulfur Atoms | 1 |
Related Chloro Standards
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Recommended Standards
- N-(2-(2,4-dichlorophenoxy)phenyl)-2,6-difluoro-3-nitrobenzamide (CAS 260553-38-6)
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- 3,3',5,5'-Tetraformyl-4,4'-biphenyldiol (CAS 286385-47-5)
- Allopseudococaine Hydrochloride (CAS 109582-53-8)
- Bromoacetylcholine (bromide) (CAS 22004-27-9)
- 3-(2,6-Dichlorophenyl)-5-methyl-N-(thiazol-2-yl)isoxazole-4-carboxamide (CAS 326902-99-2)
- Dapagliflozin Impurity 69 (CAS 3093141-55-7)
- 2-(6-Bromo-3-methylpyridin-2-yl)propan-2-amine hydrochloride (CAS 1824109-38-7)
- Z-Ala-Arg-Arg-4MbNA (J-1090.0050) (CAS 56674-16-9)
- 2-Bromo-4-(methoxymethoxy)benzaldehyde (CAS 949090-27-1)
- Des-[Oct-γ-Glu-AEEA-AEEA]-Semaglutide (CAS CATO-C4X-2226112)
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