5-(((3-Chloro-5-(trifluoromethyl)pyridin-2-yl)amino)methyl)-N-((dimethylamino)methylene)-4,5-dihydroisoxazole-3-carboxamide CAS 321432-30-8
| CAS No. | 321432-30-8 |
| Molecular Formula | C14H15ClF3N5O2 |
| Molecular Weight | 377.75 g/mol |
| Category | Pharmaceutical Standards / API Standards |
| Availability | In Stock |
Chemical Structure
Description
Compared with other compounds in its class, the molecular weight of 377.75 g/mol gives 5-(((3-Chloro-5-(trifluoromethyl)pyridin-2-yl)amino)methyl)-N-((dimethylamino)methylene)-4,5-dihydroisoxazole-3-carboxamide distinctive chromatographic separation conditions and mass-spectrometry parameter settings.
5-(((3-Chloro-5-(trifluoromethyl)pyridin-2-yl)amino)methyl)-N-((dimethylamino)methylene)-4,5-dihydroisoxazole-3-carboxamide (CAS 321432-30-8) is a high-purity analytical reference standard with the molecular formula C14H15ClF3N5O2 and a molecular weight of 377.75 g/mol.
The molecular framework of 5-(((3-Chloro-5-(trifluoromethyl)pyridin-2-yl)amino)methyl)-N-((dimethylamino)methylene)-4,5-dihydroisoxazole-3-carboxamide (C14H15ClF3N5O2) is characterized by a nitrogen-containing heterocyclic scaffold, an amide group, a hydroxyl group, an ether linkage, fluorine/chlorine substitution. In reversed-phase chromatography, its retention is governed primarily by the protonation state of its nitrogen-containing groups, which provides a practical basis for HPLC-UV/DAD or LC-MS method development. The aromatic system may exhibit native fluorescence, enabling detection with a fluorescence detector (FLD).
Recommended for analytical method development and validation; each product is supplied with a full Certificate of Analysis (COA) ensuring ISO 17034 metrological traceability.
As a certified reference material (CRM), 5-(((3-Chloro-5-(trifluoromethyl)pyridin-2-yl)amino)methyl)-N-((dimethylamino)methylene)-4,5-dihydroisoxazole-3-carboxamide meets the metrological traceability requirements of ISO/IEC 17025 laboratories. Batch-to-batch consistency is monitored via control charts to guarantee comparable assigned values across lots.
Physical & Chemical Properties
| Molecular Formula | C14H15ClF3N5O2 |
| Molecular Weight | 377.75 g/mol |
| Appearance | Pale yellow to yellow crystalline powder. (slight halide-like odor, low volatility) |
| Purity | 97%+ |
| Storage | Store at 2-8°C, protect from light, keep sealed and dry |
| Solubility (reference) | Soluble in DMSO, DMF, methanol |
| Stability | May oxidize slowly on prolonged air exposure; Light-sensitive; avoid direct strong light; Hygroscopic; reseal immediately after opening; Contains ester bond; hydrolyzes under strong alkaline conditions |
| Degree of Unsaturation (DBE) | 8.0 |
| UV Absorption | UV-absorbing |
| Structural Features | Aromatic ring present |
| CAS Registry Year (est.) | 2025 |
| Halogen Content | F/Cl-containing |
| Nitrogen Atoms | 5 |
Related Chloro Standards
- 2-(4-(3-Chloro-5-(trifluoromethyl)pyridin-2-yl)piperazine-1-carbonyl)cyclopropane-1-carboxylic acid (CAS 1023559-02-5)
- 4-(3-Chloro-5-(trifluoromethyl)pyridin-2-yl)-N-(pyridin-2-yl)benzamide (CAS 1092343-62-8)
- 4-(3-Chloro-5-(trifluoromethyl)pyridin-2-yl)-N-(pyridin-3-yl)benzamide (CAS 1092343-66-2)
- 2-[(4-chloro-3-fluoroanilino)methylidene]-4,4,4-trifluoro-1-(2-thienyl)butane-1,3-dione (CAS 649578-89-2)
- 4-((2-Chloro-5-nitrobenzylidene)amino)-3-(2-fluorophenyl)-1H-1,2,4-triazole-5(4H)-thione (CAS 578749-48-1)
- 4-((2-Chloro-5-nitrobenzylidene)amino)-3-(4-fluorophenyl)-1H-1,2,4-triazole-5(4H)-thione (CAS 577984-61-3)
- 4-((4-Chloro-3-nitrobenzylidene)amino)-3-(2-fluorophenyl)-1H-1,2,4-triazole-5(4H)-thione (CAS 578698-86-9)
- 4-((4-Chloro-3-nitrobenzylidene)amino)-3-(4-fluorophenyl)-1H-1,2,4-triazole-5(4H)-thione (CAS 585551-62-8)
Recommended Standards
- 2-(1-(2-Chloroacetyl)-3-oxopiperazin-2-yl)-N-(3-(trifluoromethyl)phenyl)acetamide (CAS 1306738-22-6)
- Benzenecarbothioicacid,[(2-hydroxyphenyl)methylene]hydrazide,palladiumcomplex (CAS 132829-27-7)
- QO-40 (CAS 1259536-70-3)
- (4Z)-1-(4-Chlorophenyl)-4-{[(2,4-difluorophenyl)amino]methylidene}-3-ethoxy-4,5-dihydro-1H-pyrazol-5-one (CAS 338751-17-0)
- 1,3,6,8-Tetrachloro-2,7-naphthyridine (CAS 27224-97-1)
- 3-Bromo-1-ethyl-5-(methylamino)-1H-pyrazole-4-carboxamide (CAS 2380036-22-4)
- Tributyl(2-(phenylthio)cyclopropyl)stannane (CAS 832132-86-2)
- 4-(2-Chlorophenyl)-3-(methylsulfonyl)-1H-pyrazole (CAS 1710696-25-5)
- 2-Bromo-1-(3-chloro-5-(trifluoromethyl)pyridin-2-yl)ethanone (CAS 856245-54-0)
- 3-[(2,4,6-trichlorophenoxy)methyl]benzohydrazide (CAS 832737-82-3)
- 2-Fluoro-N-1,N-1-dipropyl-1,4-benzenediamine (CAS 1092276-43-1)
- Daprodustat Impurity 18 (CAS 117043-46-6)
- 3,11-Difluoro-6,8,13-trimethyl-8H-quino[4,3,2-kl]acridinium Methyl Sulfate (CAS 390362-78-4)
- Des-Trp25-Tirzepatide (CAS CATO-CPTD788948)
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