4-[[6-Chloro-3-[N'-(2-chloro-3-fluorophenyl)ureido]-2-hydroxyphenyl]sulfonyl]piperazine-1-carboxylic CAS 688763-67-9
| CAS No. | 688763-67-9 |
| Molecular Formula | C22H25Cl2FN4O6S |
| Molecular Weight | 563.43 g/mol |
| Category | Pharmaceutical Standards / API Standards |
| Availability | In Stock |
Chemical Structure
Description
The molecular framework of 4-[[6-Chloro-3-[N'-(2-chloro-3-fluorophenyl)ureido]-2-hydroxyphenyl]sulfonyl]piperazine-1-carboxylic (C22H25Cl2FN4O6S) is characterized by a flavonoid core, an amide group, a sulfone group, a hydroxyl group, an ether linkage, fluorine/chlorine substitution. In reversed-phase chromatography, its retention is governed primarily by the protonation state of its nitrogen-containing groups, which provides a practical basis for HPLC-UV/DAD or LC-MS method development. Nitrogen-containing functional groups confer excellent ionization efficiency in positive-ion electrospray (ESI) mode, making the compound well suited to LC-MS/MS analysis.
4-[[6-Chloro-3-[N'-(2-chloro-3-fluorophenyl)ureido]-2-hydroxyphenyl]sulfonyl]piperazine-1-carboxylic (CAS 688763-67-9) is a high-purity analytical reference standard with the molecular formula C22H25Cl2FN4O6S and a molecular weight of 563.43 g/mol.
Recommended for analytical method development and validation; each product is supplied with a full Certificate of Analysis (COA) ensuring ISO 17034 metrological traceability.
The assigned purity is verified by mass-balance and quantitative NMR (qNMR) approaches, with the expanded uncertainty reported at a 95% confidence level (k=2). Batch homogeneity and stability are independently assessed for every lot.
Physical & Chemical Properties
| Molecular Formula | C22H25Cl2FN4O6S |
| Molecular Weight | 563.43 g/mol |
| Purity | 97%+ |
| Storage | Store in a cool place (≤25°C), protect from light, keep sealed and dry |
| Solubility (reference) | Soluble in DMSO, DMF, methanol |
| Stability | May oxidize slowly on prolonged air exposure; Light-sensitive; avoid direct strong light; Hygroscopic; reseal immediately after opening; Contains ester bond; hydrolyzes under strong alkaline conditions |
| Degree of Unsaturation (DBE) | 11.0 |
| UV Absorption | UV-absorbing |
| Structural Features | Aromatic ring present |
| CAS Registry Year (est.) | 1985 |
| Halogen Content | F/Cl-containing |
| Nitrogen Atoms | 4 |
| Sulfur Atoms | 1 |
Related Chloro Standards
- 3-Chloro-2-(4-{[3-(2-phenyl-1,3-thiazol-5-yl)-1H-pyrazol-1-yl]sulfonyl}phenoxy)-5-(trifluoromethyl)pyridine (CAS 318255-89-9)
- Ethyl 5-{[3-chloro-5-(trifluoromethyl)pyridin-2-yl](methyl)amino}-3-(1,3-dioxo-2,3-dihydro-1H-inden-2-ylidene)-4,6-dioxo-octahydropyrrolo[3,4-c]pyrrole-1-carboxylate (CAS 321522-13-8)
- 5-Chloro-6-nitrospiro[chroman-2,2'-indole] (CAS 26456-32-6)
- 1-Des(3-chloro-2-pyridinyl)-1-(3-chloro-5-bromo-2-pyridinyl)chlorantraniliprole (CAS 500011-53-0)
- 1-(2-{[3-chloro-5-(trifluoromethyl)pyridin-2-yl]amino}ethyl)-3-methyl-5-[(2E)-3-{[4-(trifluoromethyl)phenyl]amino}prop-2-enoyl]-1,2,3,4-tetrahydropyrimidine-2,4-dione (CAS 338770-35-7)
- Methyl 6-chloro-1-naphthoate (CAS 5471-30-7)
- 3-Benzyl-8-(3-chloro-5-(trifluoromethyl)pyridin-2-yl)-N-(4-chlorophenyl)-1-oxa-4,8-diazaspiro[4.5]Decane-4-carboxamide (CAS 338963-08-9)
- 3-Chloro-2-[(Z)-2-(1-{3-[(4-chlorobenzenesulfonyl)methyl]-4-nitrophenyl}ethylidene)-1-methylhydrazin-1-yl]-5-(trifluoromethyl)pyridine (CAS 339016-36-3)
Recommended Standards
- 2,5-Bis(2,2,2-trifluoroethoxy)-N-[2-({[4-(trifluoromethoxy)phenyl]carbamoyl}amino)ethyl]benzamide (CAS 338404-68-5)
- N-Formyl-Met-Leu-p-Iodo-Phe (CAS 105931-59-7)
- Methylstannanetriyl tris(2-ethylhexanoate) (CAS 62312-12-3)
- CZ89-2Brc (CAS 1268491-06-0)
- 3-(5-Bromothiophen-2-yl)-3-hydroxypropanoic acid (CAS 1249697-76-4)
- 240408-81-5 T9X7TNF4X2 Triglycidyl isocyanurate, (S,S,S)- UNII-T9X7TNF4X2 beta-Triglycidyl isocyanurate, (-)- 1,3,5-Triazine-2,4,6(1H,3H,5H)-trione, 1,3,5-tris((2S)-2-oxiranylmethyl)- 1,3,5-Triazine-2,4,6(1H,3H,5H)-trione, 1,3,5-tris((2S)-oxiranylmethyl)- (S,S,S)-Triglycidyl isocyanurate (CAS 240408-81-5)
- rel-(3S,4R,5R)-1-Amino-3,4,5,6-tetrahydroxyhexan-2-one (CAS 27968-74-7)
- 2-(Pent-4-en-1-yl)-1,3-dioxane (CAS 80634-89-5)
- 3,4-Dimethoxybenzaldehyde-d3 (CAS 143318-06-3)
- 4-Chloro-2-methylisoquinolin-1(2H)-one (CAS 27187-01-5)
- 1-Bromo-2-methyl-4-(trifluoromethoxy)benzene (CAS 261951-96-6)
- 3-((6-Chloropyridin-3-yl)methyl)thieno[3,2-d]pyrimidin-4(3h)-one (CAS 1096907-30-0)
- 1-[3-(aminomethyl)phenyl]-3-cyclopropylurea hydrochloride (CAS 1240527-87-0)
- Semaglutide impurity 51 (CAS CATO-C4X-222651)
Why CATO?
- ISO 17034 accredited reference material producer (CNAS + ANAB dual accreditation)
- 130,000+ catalog items in stock, COA supplied with every batch
- Worldwide shipping with full export documentation (HS code guidance available)
- Technical support: +86 18665070610 / Nicole.chen@cato-chem.com