Methyl 3-(2-chlorophenyl)-5-(3-(ethoxycarbonyl)-1-(p-tolyl)-1H-pyrazol-4-yl)isoxazole-4-carboxylate CAS 321571-26-0
| CAS No. | 321571-26-0 |
| Molecular Formula | C24H20ClN3O5 |
| Molecular Weight | 465.89 g/mol |
| Category | Pharmaceutical Standards / API Standards |
| Availability | In Stock |
Chemical Structure
Description
The molecular framework of Methyl 3-(2-chlorophenyl)-5-(3-(ethoxycarbonyl)-1-(p-tolyl)-1H-pyrazol-4-yl)isoxazole-4-carboxylate (C24H20ClN3O5) is characterized by a flavonoid core, an amide group, a hydroxyl group, an ether linkage, chlorine substitution. In reversed-phase chromatography, its retention is governed primarily by the protonation state of its nitrogen-containing groups, which provides a practical basis for HPLC-UV/DAD or LC-MS method development. The aromatic system may exhibit native fluorescence, enabling detection with a fluorescence detector (FLD).
Methyl 3-(2-chlorophenyl)-5-(3-(ethoxycarbonyl)-1-(p-tolyl)-1H-pyrazol-4-yl)isoxazole-4-carboxylate (CAS 321571-26-0), molecular formula C24H20ClN3O5 and molecular weight 465.89 g/mol, is a CATO reference standard with documented purity and traceability.
This reference standard is suitable for quantitative analysis on major chromatographic platforms including HPLC, GC, LC-MS/MS, and GC-MS, serving as an external calibration standard or a system suitability test reference material.
CATO manufactures Methyl 3-(2-chlorophenyl)-5-(3-(ethoxycarbonyl)-1-(p-tolyl)-1H-pyrazol-4-yl)isoxazole-4-carboxylate under ISO 17034:2016 accreditation with dual CNAS and ANAB accreditation. Each batch is characterized by orthogonal methods and supplied with a full Certificate of Analysis (COA), ensuring metrological traceability.
Physical & Chemical Properties
| Molecular Formula | C24H20ClN3O5 |
| Molecular Weight | 465.89 g/mol |
| Appearance | Pale yellow to yellow crystalline powder. (slight halide-like odor) |
| Purity | 97%+ |
| Storage | Store in a cool place (≤25°C), protect from light, keep sealed and dry |
| Solubility (reference) | Soluble in DMSO, DMF, methanol |
| Stability | May oxidize slowly on prolonged air exposure; Light-sensitive; avoid direct strong light; Hygroscopic; reseal immediately after opening; Contains ester bond; hydrolyzes under strong alkaline conditions |
| Degree of Unsaturation (DBE) | 16.0 |
| UV Absorption | UV-absorbing |
| Structural Features | Aromatic ring present |
| CAS Registry Year (est.) | 2025 |
| Halogen Content | Cl-containing |
| Nitrogen Atoms | 3 |
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Recommended Standards
- N'1-(2-chloroacetyl)-2-({4-(3-methoxypropyl)-5-[4-(trifluoromethyl)phenyl]-4H-1,2,4-triazol-3-yl}thio)ethanohydrazide (CAS 261966-45-4)
- Tadalafil Impurity 109 (CAS CATO-C4X-1087109)
- 3,6,8-Tribromo-2-(5-nitrofuran-2-yl)imidazo[1,2-a]pyridine (CAS 61982-68-1)
- 7-(3-((tert-Butoxycarbonyl)amino)pyrrolidin-1-yl)-8-chloro-1-cyclopropyl-6-fluoro-4-oxo-1,4-dihydroquinoline-3-carboxylic acid (CAS 105956-96-5)
- 4-Hydroxy-3-isopropoxybenzoic acid (CAS 99186-66-0)
- 2-(1h-1,2,3,4-Tetrazol-1-yl)ethan-1-amine hydrochloride (CAS 1201937-23-6)
- (4,5-Dimethyl-2-nitrophenyl)hydrazine (CAS 1248766-92-8)
- 2-chloro-1-(chloromethyl)-3,4-difluorobenzene (CAS 1807166-53-5)
- N1-Cycloheptyl-N2-((4-oxo-3,4-dihydrophthalazin-1-yl)methyl)oxalamide (CAS 946298-46-0)
- 8-Chloro-1,6-naphthyridine (CAS 1309379-16-5)
- 1-Oxo-1,2,3,4-tetrahydroisoquinolin-6-yl trifluoromethanesulfonate (CAS 897374-38-8)
- Ethyl 2,6-dichloronicotinate (CAS 58584-86-4)
- Manganese(II) phosphate hydrate (CAS 109135-78-6)
- Ac-(5-31)Semaglutide (CAS CATO-C4X-2226279)
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