Levothyroxine Methyl Ester CAS 32180-11-3
| CAS No. | 32180-11-3 |
| Molecular Formula | C16H13I4NO4 |
| Molecular Weight | 790.90 g/mol |
| Category | Pharmaceutical Standards / API Standards |
| Availability | In Stock |
Chemical Structure
Description
Levothyroxine Methyl Ester (CAS 32180-11-3) is a high-purity analytical reference standard with the molecular formula C16H13I4NO4 and a molecular weight of 790.90 g/mol.
Based on its molecular formula C16H13I4NO4, Levothyroxine Methyl Ester contains a flavonoid core, an amide group, a hydroxyl group, an ether linkage, iodine substitution; these features give the compound characteristic absorption bands in UV spectroscopy. The molecular weight of 790.90 g/mol is directly relevant to the identification of the molecular ion in mass spectrometry. Nitrogen-containing functional groups confer excellent ionization efficiency in positive-ion electrospray (ESI) mode, making the compound well suited to LC-MS/MS analysis.
This reference standard is suitable for quantitative analysis on major chromatographic platforms including HPLC, GC, LC-MS/MS, and GC-MS, serving as an external calibration standard or a system suitability test reference material.
The assigned purity is verified by mass-balance and quantitative NMR (qNMR) approaches, with the expanded uncertainty reported at a 95% confidence level (k=2). Batch homogeneity and stability are independently assessed for every lot.
Physical & Chemical Properties
| Molecular Formula | C16H13I4NO4 |
| Molecular Weight | 790.90 g/mol |
| Purity | 97%+ |
| Storage | Store at room temperature, protect from light, keep sealed and dry |
| Solubility (reference) | Soluble in methanol, acetonitrile, DMSO, water (slightly soluble) |
| Stability | May oxidize slowly on prolonged air exposure; Light-sensitive; avoid direct strong light; Contains ester bond; hydrolyzes under strong alkaline conditions |
| Degree of Unsaturation (DBE) | 9.0 |
| UV Absorption | UV-absorbing |
| Structural Features | Aromatic ring present |
| CAS Registry Year (est.) | 1966 |
| Halogen Content | I-containing |
| Nitrogen Atoms | 1 |
Related Levothyroxine Standards
- Levothyroxine Impurity 24 (CAS CATO-C4X-167824)
- Levothyroxine N-Methylamide (CAS 2088032-52-2)
- Levothyroxine Impurity 30 (CAS 107849-54-7)
- Levothyroxine impurity 47 (CAS CATO-C4X-167847)
- Levothyroxine D3 (CAS CATO-C4X-167856)
- Levothyroxine Impurity 20 (CAS 7069-47-8)
- Levothyroxine Impurity 27 (CAS 671235-41-9)
- Levothyroxine Ethyl Ester (CAS 76353-71-4)
Recommended Standards
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