Levothyroxine impurity 47 CAS CATO-C4X-167847
| CAS No. | CATO-C4X-167847 |
| Molecular Formula | C15H11I4NO5 |
| Molecular Weight | 792.87 g/mol |
| Category | Pharmacopoeial Impurity Standards / EP Impurities |
| Availability | In Stock |
Chemical Structure
Description
As a certified reference material (CRM), Levothyroxine impurity 47 meets the metrological traceability requirements of ISO/IEC 17025 laboratories. Batch-to-batch consistency is monitored via control charts to guarantee comparable assigned values across lots.
CATO supplies Levothyroxine impurity 47 (CAS CATO-C4X-167847), a pharmacopoeial impurity reference standard (molecular formula C15H11I4NO5, MW 792.87 g/mol) used for the identification and quantification of trace impurities in APIs.
Based on its molecular formula C15H11I4NO5, Levothyroxine impurity 47 contains a flavonoid core, an amide group, a hydroxyl group, an ether linkage, iodine substitution; these features give the compound characteristic absorption bands in UV spectroscopy. The molecular weight of 792.87 g/mol is directly relevant to the identification of the molecular ion in mass spectrometry. The aromatic system may exhibit native fluorescence, enabling detection with a fluorescence detector (FLD).
Recommended for quantitative analysis by HPLC, GC, LC-MS/MS, or GC-MS as an external calibration standard; it can also be used for spiked-recovery experiments, LOD/LOQ determination, and LC-MS/MS multiple-reaction-monitoring (MRM) calibration.
Physical & Chemical Properties
| Molecular Formula | C15H11I4NO5 |
| Molecular Weight | 792.87 g/mol |
| Purity | 97%+ |
| Storage | Store at room temperature, protect from light, keep sealed and dry |
| Solubility (reference) | Soluble in methanol, acetonitrile, DMSO, water (slightly soluble) |
| Stability | May oxidize slowly on prolonged air exposure; Light-sensitive; avoid direct strong light; Contains ester bond; hydrolyzes under strong alkaline conditions |
| Degree of Unsaturation (DBE) | 9.0 |
| UV Absorption | UV-absorbing |
| Structural Features | Aromatic ring present |
| Halogen Content | I-containing |
| Nitrogen Atoms | 1 |
Related Levothyroxine Standards
- Levothyroxine Impurity 30 (CAS 107849-54-7)
- Levothyroxine Methyl Ester (CAS 32180-11-3)
- Levothyroxine Impurity 24 (CAS CATO-C4X-167824)
- Levothyroxine N-Methylamide (CAS 2088032-52-2)
- Levothyroxine Impurity 27 (CAS 671235-41-9)
- Levothyroxine Ethyl Ester (CAS 76353-71-4)
- Levothyroxine D3 (CAS CATO-C4X-167856)
- Levothyroxine Impurity 20 (CAS 7069-47-8)
Recommended Standards
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- trans-(E)-Flupentixol (CAS 53772-85-3)
- Alectinib Impurity 5 (CAS 1247119-83-0)
- N-Butyl-2-(2-methoxyphenyl)-5-methylpyrazolo[1,5-a]pyrimidin-7-amine (CAS 950301-10-7)
- 2,3-Difluoro-5-(trifluoromethyl)phenol (CAS 164790-01-6)
- D-Leu14-Tirzepatide (CAS CATO-CPTD788920)
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