Nicotine Impurity 7 CAS 3222-49-9

Purity >95%In StockPharmacopoeial Impurity Standards
CAS No.3222-49-9
Molecular FormulaC7H7NO2
Molecular Weight137.14 g/mol
CategoryPharmacopoeial Impurity Standards / EP Impurities
AvailabilityIn Stock

Chemical Structure

Nicotine Impurity 7 CAS 3222-49-9 chemical structure

Description

As a process- or degradation-related impurity, Nicotine Impurity 7 (CAS 3222-49-9, C7H7NO2) is essential for impurity profiling, related-substances testing, and forced-degradation studies in pharmaceutical development.

Nicotine Impurity 7 (C7H7NO2) contains an amino-acid-derived structure, an amide group, a hydroxyl group, an ether linkage. The carboxyl group imparts weak acidity; these physicochemical properties determine the optimal preparation and storage of its standard solutions. Nitrogen-containing functional groups confer excellent ionization efficiency in positive-ion electrospray (ESI) mode, making the compound well suited to LC-MS/MS analysis.

This reference standard supports related-substances testing and method development in line with ICH Q3A/Q3B guidance on impurity control, and is suitable for system suitability testing and forced-degradation studies.

CATO manufactures Nicotine Impurity 7 under ISO 17034:2016 accreditation with dual CNAS and ANAB accreditation. Each batch is characterized by orthogonal methods and supplied with a full Certificate of Analysis (COA), ensuring metrological traceability.

Physical & Chemical Properties

Molecular FormulaC7H7NO2
Molecular Weight137.14 g/mol
Purity>95%
StorageStore at 2-8°C, protect from light
Solubility (reference)Soluble in methanol, acetonitrile, DMSO, water (slightly soluble)
StabilityMay oxidize slowly on prolonged air exposure; Light-sensitive; avoid direct strong light
Degree of Unsaturation (DBE)5.0
UV AbsorptionUV-absorbing
Structural FeaturesAromatic ring present
CAS Registry Year (est.)1957
Nitrogen Atoms1

Related Nicotine Standards

Recommended Standards

Why CATO?