Bupropion (S)-Isomer Hydrochloride CAS 324548-45-0
| CAS No. | 324548-45-0 |
| Molecular Formula | C13H18ClNO |
| Molecular Weight | N/A |
| Category | Pharmaceutical Standards / API Standards |
| Availability | In Stock |
Chemical Structure
Description
This reference standard is suitable for quantitative analysis on major chromatographic platforms including HPLC, GC, LC-MS/MS, and GC-MS, serving as an external calibration standard or a system suitability test reference material.
CATO supplies Bupropion (S)-Isomer Hydrochloride (CAS 324548-45-0), a certified reference material (molecular formula C13H18ClNOHCl, MW 276.20 g/mol) for analytical method development and quality control.
The molecular framework of Bupropion (S)-Isomer Hydrochloride (C13H18ClNOHCl) is characterized by a nitrogen-containing heterocyclic scaffold, an amide group, a hydroxyl group, an ether linkage, chlorine substitution. In reversed-phase chromatography, its retention is governed primarily by its high hydrophobicity (logP), which provides a practical basis for HPLC-UV/DAD or LC-MS method development. Nitrogen-containing functional groups confer excellent ionization efficiency in positive-ion electrospray (ESI) mode, making the compound well suited to LC-MS/MS analysis.
As a certified reference material (CRM), Bupropion (S)-Isomer Hydrochloride meets the metrological traceability requirements of ISO/IEC 17025 laboratories. Batch-to-batch consistency is monitored via control charts to guarantee comparable assigned values across lots.
Physical & Chemical Properties
| Molecular Formula | C13H18ClNO HCl |
| Molecular Weight | 276.20 g/mol |
| Purity | 97%+ |
| Storage | Store at 2-8°C, protect from light, keep tightly closed to prevent evaporation |
| Solubility (reference) | Soluble in chloroform, dichloromethane, ethyl acetate, DMSO |
| Stability | May oxidize slowly on prolonged air exposure; Light-sensitive; avoid direct strong light |
| Degree of Unsaturation (DBE) | 4.0 |
| UV Absorption | UV-absorbing |
| Structural Features | Aromatic ring present |
| CAS Registry Year (est.) | 2025 |
| Halogen Content | Cl-containing |
| Nitrogen Atoms | 1 |
Related Bupropion Standards
- Bupropion Impurity 72 (CAS 102141-11-7)
- Bupropion Impurity 71 (CAS 102141-12-8)
- Bupropion Impurity 9 (CAS 103175-61-7)
- Bupropion Hydrochloride USP Related Compound B (CAS 1049718-43-5)
- Bupropion Hydrochloride USP Related Compound A (CAS 1049718-72-0)
- Bupropion impurity 67 (CAS 1049974-40-4)
- Bupropion Impurity 17 (CAS 10557-17-2)
- Bupropion Morpholinol Impurity (HCl Salt) (CAS 106083-71-0)
Recommended Standards
- methyl 2-azabicyclo[2.2.1]heptane-1-carboxylate;hydrochloride (CAS 1824224-77-2)
- tert-Butyl (3S,4R)-3-fluoro-4-((methylsulfonyl)oxy)pyrrolidine-1-carboxylate (CAS 1432129-10-6)
- 6-Phenyl-1,2,4-triazin-3(2h)-one (CAS 23448-86-4)
- (S)-3,3'-Bis(3,5-bis(trifluoromethyl)phenyl)-[1,1'-binaphthalene]-2,2'-diol 849939-13-5 (CAS 849939-13-5)
- 6-Chloro-3-(piperidin-4-yl)-1h-indole (CAS 180160-78-5)
- Pipracil (CAS 61477-96-1)
- 4-(Chloromethyl)-2-(3-ethylphenyl)oxazole (CAS 1393576-88-9)
- 5-(chloromethyl)-3-(2-ethoxyphenyl)-1,2,4-oxadiazole (CAS 923239-59-2)
- 4-(Methylamino)-2-(methylthio)pyrimidin-5-yl)methanol, 97% (CAS 17759-30-7)
- Semaglutide impurity 88 (CAS CATO-C4X-222688)
Why CATO?
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