Bupropion Impurity 17 CAS 10557-17-2

Purity >90%In StockPharmacopoeial Impurity Standards
CAS No.10557-17-2
Molecular FormulaC9H7ClO2
Molecular Weight182.60 g/mol
CategoryPharmacopoeial Impurity Standards / EP Impurities
AvailabilityIn Stock

Chemical Structure

Bupropion Impurity 17 CAS 10557-17-2 chemical structure

Description

Under current pharmacopoeial and regulatory frameworks, quality-control requirements for this class of reference material explicitly involve the control of targets including Bupropion Impurity 17.

Bupropion Impurity 17 (CAS 10557-17-2) is a certified pharmaceutical impurity reference standard with the molecular formula C9H7ClO2 and a molecular weight of 182.60 g/mol.

Owing to a carboxylic acid group, a hydroxyl group, an ether linkage, chlorine substitution, an aromatic ring system, Bupropion Impurity 17 is typically off-white to pale yellow crystalline powder. Its solid-state physicochemical attributes — including a molecular weight of 182.60 g/mol — guide the selection of appropriate sample preparation and analytical techniques. The presence of an aromatic ring or conjugated system gives the compound characteristic absorption bands in the UV-Vis region, making it well suited to UV or diode-array detection (DAD).

Recommended for quantitative analysis by HPLC, GC, LC-MS/MS, or GC-MS as an external calibration standard; it can also be used for spiked-recovery experiments, LOD/LOQ determination, and LC-MS/MS multiple-reaction-monitoring (MRM) calibration.

CATO manufactures Bupropion Impurity 17 under ISO 17034:2016 accreditation with dual CNAS and ANAB accreditation. Each batch is characterized by orthogonal methods and supplied with a full Certificate of Analysis (COA), ensuring metrological traceability.

Physical & Chemical Properties

Molecular FormulaC9H7ClO2
Molecular Weight182.60 g/mol
AppearanceOff-white to pale yellow crystalline powder. (slight halide-like odor)
Purity>90%
StorageStore at 2-8°C, protect from light, keep tightly closed to prevent evaporation
Solubility (reference)Soluble in methanol, acetonitrile, DMSO, water (slightly soluble)
StabilityMay oxidize slowly on prolonged air exposure; Light-sensitive; avoid direct strong light; Contains ester bond; hydrolyzes under strong alkaline conditions
Degree of Unsaturation (DBE)6.0
UV AbsorptionUV-absorbing
Structural FeaturesAromatic ring present
CAS Registry Year (est.)1960
Halogen ContentCl-containing

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