Etofenamate EP Impurity G CAS 32508-98-8
| CAS No. | 32508-98-8 |
| Molecular Formula | C16H14F3NO3 |
| Molecular Weight | 325.28 g/mol |
| Category | Pharmacopoeial Impurity Standards / EP Impurities |
| Availability | In Stock |
Chemical Structure
Description
As a certified reference material (CRM), Etofenamate EP Impurity G meets the metrological traceability requirements of ISO/IEC 17025 laboratories. Batch-to-batch consistency is monitored via control charts to guarantee comparable assigned values across lots.
As a process- or degradation-related impurity, Etofenamate EP Impurity G (CAS 32508-98-8, C16H14F3NO3) is essential for impurity profiling, related-substances testing, and forced-degradation studies in pharmaceutical development.
Etofenamate EP Impurity G (C16H14F3NO3) contains a nitrogen-containing heterocyclic scaffold, an amide group, a hydroxyl group, an ether linkage, fluorine substitution. Halogen substitution raises its density and boiling point, its high carbon-to-hydrogen ratio confers good lipid solubility, the carboxyl group imparts weak acidity; these physicochemical properties determine the optimal preparation and storage of its standard solutions. Nitrogen-containing functional groups confer excellent ionization efficiency in positive-ion electrospray (ESI) mode, making the compound well suited to LC-MS/MS analysis.
Recommended for quantitative analysis by HPLC, GC, LC-MS/MS, or GC-MS as an external calibration standard; it can also be used for spiked-recovery experiments, LOD/LOQ determination, and LC-MS/MS multiple-reaction-monitoring (MRM) calibration.
Physical & Chemical Properties
| Molecular Formula | C16H14F3NO3 |
| Molecular Weight | 325.28 g/mol |
| Appearance | Pale yellow to yellow crystalline powder. (slight halide-like odor, low volatility) |
| Purity | >95% |
| Storage | Store at 2-8°C, protect from light, keep sealed and dry |
| Solubility (reference) | Soluble in chloroform, dichloromethane, ethyl acetate, DMSO |
| Stability | May oxidize slowly on prolonged air exposure; Light-sensitive; avoid direct strong light; Contains ester bond; hydrolyzes under strong alkaline conditions |
| Degree of Unsaturation (DBE) | 9.0 |
| UV Absorption | UV-absorbing |
| Structural Features | Aromatic ring present |
| CAS Registry Year (est.) | 1966 |
| Halogen Content | F-containing |
| Nitrogen Atoms | 1 |
Related Etofenamate Standards
- Etofenamate Impurity N9 (CAS 68749-59-7)
- Etofenamate Impurity 10 (CAS CATO-C4X-260310)
- Etofenamate Impurity 9 (CAS CATO-C4X-26039)
- Etofenamate Impurity 11 (CAS CATO-C4X-260311)
- Etofenamate Impurity 13 (CAS CATO-C4X-260313)
- Etofenamate (CAS 30544-47-9)
- Etofenamate Impurity 12 (CAS CATO-C4X-260312)
- Etofenamate Impurity 2 (CAS CATO-C4X-26032)
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