Tamsulosin Impurity 48 CAS 3259-03-8
| CAS No. | 3259-03-8 |
| Molecular Formula | C10H13BrO2 |
| Molecular Weight | 245.11 g/mol |
| Category | Pharmacopoeial Impurity Standards / EP Impurities |
| Availability | In Stock |
Chemical Structure
Description
Under current pharmacopoeial and regulatory frameworks, quality-control requirements for this class of reference material explicitly involve the control of targets including Tamsulosin Impurity 48.
CATO supplies Tamsulosin Impurity 48 (CAS 3259-03-8), a pharmacopoeial impurity reference standard (molecular formula C10H13BrO2, MW 245.11 g/mol) used for the identification and quantification of trace impurities in APIs.
The molecular framework of Tamsulosin Impurity 48 (C10H13BrO2) is characterized by a carboxylic acid group, a hydroxyl group, an ether linkage, bromine substitution, an aromatic ring system. In reversed-phase chromatography, its retention is governed primarily by its high hydrophobicity (logP), which provides a practical basis for HPLC-UV/DAD or LC-MS method development. Halogen substitution (F/Cl/Br/I) produces a distinctive isotope pattern in mass spectrometry, a valuable aid for qualitative confirmation.
This reference standard supports related-substances testing and method development in line with ICH Q3A/Q3B guidance on impurity control, and is suitable for system suitability testing and forced-degradation studies.
CATO manufactures Tamsulosin Impurity 48 under ISO 17034:2016 accreditation with dual CNAS and ANAB accreditation. Each batch is characterized by orthogonal methods and supplied with a full Certificate of Analysis (COA), ensuring metrological traceability.
Physical & Chemical Properties
| Molecular Formula | C10H13BrO2 |
| Molecular Weight | 245.11 g/mol |
| Appearance | Off-white to pale yellow crystalline powder. (slight halide-like odor) |
| Purity | 97%+ |
| Storage | Store at room temperature, keep tightly closed to prevent evaporation |
| Solubility (reference) | Soluble in chloroform, dichloromethane, ethyl acetate, DMSO |
| Stability | May oxidize slowly on prolonged air exposure; Contains ester bond; hydrolyzes under strong alkaline conditions |
| Degree of Unsaturation (DBE) | 4.0 |
| UV Absorption | UV-absorbing |
| Structural Features | Aromatic ring present |
| CAS Registry Year (est.) | 1957 |
| Halogen Content | Br-containing |
Related Tamsulosin Standards
- Tamsulosin Impurity 62 (CAS 54646-18-3)
- Tamsulosin Impurity 21 (CAS 1396967-49-9)
- Tamsulosin Impurity 32 (CAS 112244-38-9)
- Tamsulosin EP Impurity B (CAS 112101-81-2)
- Tamsulosin Impurity 44 (CAS 119714-13-5)
- Tamsulosin Impurity 41 (CAS CATO-C4X-118741)
- Tamsulosin Impurity 19 (CAS 116091-63-5)
- Tamsulosin Impurity 70 (CAS CATO-C4X-118770)
Recommended Standards
- methyl 4-(2-bromoethynyl)benzoate (CAS 225928-10-9)
- Apraclonidine (CAS 66711-21-5)
- Lusutrombopag Impurity 79 (CAS CATO-C4X-208479)
- 7-Chloro-6-(2-chloropropyl)-5-methyl-[1,2,4]triazolo[1,5-a]pyrimidine (CAS 62053-07-0)
- Latanoprost Impurity 12 (CAS 125637-06-1)
- Apixaban Impurity 10 (CAS 1421823-20-2)
- Sulfamethoxazole EP Impurity B (CAS 135529-16-7)
- 5-(3-Methylphenyl)-1-pentene (CAS 51125-15-6)
- N,N-Dimethyl-2-(phenylethynyl)aniline (CAS 54655-08-2)
- 3,5-Dichlorobenzyl piperazine-1-carboxylate (CAS 1144037-37-5)
- n-(1-Methoxypropan-2-yl)-4-(methylthio)aniline (CAS 1250298-30-6)
- Heptyl Chlorosulfinate (CAS 876478-61-4)
- 5-Fluoro-2-(tetramethyl-1,3,2-dioxaborolan-2-yl)pyridine-4-carbaldehyde (CAS 1356930-47-6)
- Semaglutide Impurity 166 (CAS 1395881-03-4)
Why CATO?
- ISO 17034 accredited reference material producer (CNAS + ANAB dual accreditation)
- 130,000+ catalog items in stock, COA supplied with every batch
- Worldwide shipping with full export documentation (HS code guidance available)
- Technical support: +86 18665070610 / Nicole.chen@cato-chem.com