N-(4-(2,5-Dichlorothiophen-3-yl)thiazol-2-yl)-4-(pyrrolidin-1-ylsulfonyl)benzamide CAS 325988-92-9
| CAS No. | 325988-92-9 |
| Molecular Formula | C18H15Cl2N3O3S3 |
| Molecular Weight | 488.43 g/mol |
| Category | Pharmaceutical Standards / API Standards |
| Availability | In Stock |
Chemical Structure
Description
N-(4-(2,5-Dichlorothiophen-3-yl)thiazol-2-yl)-4-(pyrrolidin-1-ylsulfonyl)benzamide (CAS 325988-92-9), molecular formula C18H15Cl2N3O3S3 and molecular weight 488.43 g/mol, is a CATO reference standard with documented purity and traceability.
Owing to a steroid core, an amide group, a sulfone group, a hydroxyl group, an ether linkage, chlorine substitution, N-(4-(2,5-Dichlorothiophen-3-yl)thiazol-2-yl)-4-(pyrrolidin-1-ylsulfonyl)benzamide is typically pale yellow to yellow crystalline powder. Its solid-state physicochemical attributes — including a molecular weight of 488.43 g/mol — guide the selection of appropriate sample preparation and analytical techniques. The presence of an aromatic ring or conjugated system gives the compound characteristic absorption bands in the UV-Vis region, making it well suited to UV or diode-array detection (DAD).
This reference standard is suitable for quantitative analysis on major chromatographic platforms including HPLC, GC, LC-MS/MS, and GC-MS, serving as an external calibration standard or a system suitability test reference material.
As a certified reference material (CRM), N-(4-(2,5-Dichlorothiophen-3-yl)thiazol-2-yl)-4-(pyrrolidin-1-ylsulfonyl)benzamide meets the metrological traceability requirements of ISO/IEC 17025 laboratories. Batch-to-batch consistency is monitored via control charts to guarantee comparable assigned values across lots.
Physical & Chemical Properties
| Molecular Formula | C18H15Cl2N3O3S3 |
| Molecular Weight | 488.43 g/mol |
| Purity | 97%+ |
| Storage | Store in a cool place (≤25°C), protect from light, keep sealed and dry |
| Solubility (reference) | Soluble in DMSO, DMF, methanol |
| Stability | May oxidize slowly on prolonged air exposure; Light-sensitive; avoid direct strong light; Hygroscopic; reseal immediately after opening; Contains ester bond; hydrolyzes under strong alkaline conditions |
| Degree of Unsaturation (DBE) | 12.0 |
| UV Absorption | UV-absorbing |
| Structural Features | Aromatic ring present |
| CAS Registry Year (est.) | 2025 |
| Halogen Content | Cl-containing |
| Nitrogen Atoms | 3 |
| Sulfur Atoms | 3 |
Related N Standards
- N-(5-(2,5-Dichlorothiophen-3-yl)-1,3,4-oxadiazol-2-yl)-2-(2-fluorophenoxy)acetamide (CAS 1170257-15-4)
- 4-(2,5-Dichlorothiophen-3-yl)-2-{[(4-methoxyphenyl)methyl]sulfanyl}pyrimidine (CAS 338750-36-0)
- N-(5-(2,5-Dichlorothiophen-3-yl)-1,3,4-oxadiazol-2-yl)-2-(4-fluorophenyl)acetamide (CAS 1171906-91-4)
- 4-(2,5-Dichlorothiophen-3-yl)-2-{[(2-methylphenyl)methyl]sulfanyl}pyrimidine (CAS 338777-22-3)
- 4-(2,5-Dichlorothiophen-3-yl)-2-{[(3-methylphenyl)methyl]sulfanyl}pyrimidine (CAS 343374-82-3)
- 4-(2,5-Dichlorothiophen-3-yl)-2-{[(4-methylphenyl)methyl]sulfanyl}pyrimidine (CAS 338777-23-4)
- Methyl 2-((2-(2,5-dichlorothiophen-3-yl)-2-oxoethyl)thio)benzoate (CAS 338401-90-4)
- (2E)-1-(2,5-Dichlorothiophen-3-yl)-3-[(3,4-dimethoxyphenyl)amino]prop-2-en-1-one (CAS 338402-48-5)
Recommended Standards
- N-((1'-benzyl-4',5'-dimethyl-1'H-[1,2'-bipyrrol]-3'-yl)methyl)-3,5-dichlorobenzenesulfonamide (CAS 478077-23-5)
- Tris[2-(1H-pyrazol-1-yl)phenyl]cobalt (CAS 62572-61-6)
- 5-(2,2-Dimethyl-1,3-dioxolan-4-yl)-3,4-bis[2-(4-fluorophenyl)-2-oxoethoxy]-2,5-dihydrofuran-2-one (CAS 866151-25-9)
- Aripiprazole-d8 N,N-Dioxide (CAS 1346603-98-2)
- 3-Chloro-2-ethoxy-5-methylbenzaldehyde (CAS 883522-32-5)
- 5-Chloro-6-methoxynicotinaldehyde (CAS 132865-44-2)
- 4-[(2-Methylpentyl)oxy]-3-(trifluoromethyl)aniline (CAS 946775-64-0)
- 2-(2-Trifluoromethyl-benzoimidazol-1-yl)-propionic acid hydrochloride (CAS 1219422-80-6)
- N-Isopropyl-N-methyl-1-phenylpropan-2-amine (CAS 66514-90-7)
- 2-((3-Fluorobenzyl)sulfonyl)-1-methyl-4,5-diphenyl-1H-imidazole (CAS 338957-03-2)
- 3-{[benzyl(methyl)amino]methyl}benzoic acid hydrochloride (CAS 1461713-70-1)
- 1,2-Dimethyl-3-Nitroguanidine (CAS 101250-97-9)
- (Perchlorophenyl)(propyl)sulfane (CAS 221031-78-3)
- D-Ala21-Tirzepatide (CAS CATO-CPTD788913)
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