Vonoprazan Impurity 105 CAS CATO-C4X-1020105
| CAS No. | CATO-C4X-1020105 |
| Molecular Formula | C17H20FN3O2S |
| Molecular Weight | 349.42 g/mol |
| Category | Pharmacopoeial Impurity Standards / EP Impurities |
| Availability | In Stock |
Chemical Structure
Description
As a certified reference material (CRM), Vonoprazan Impurity 105 meets the metrological traceability requirements of ISO/IEC 17025 laboratories. Batch-to-batch consistency is monitored via control charts to guarantee comparable assigned values across lots.
Vonoprazan Impurity 105 (CAS CATO-C4X-1020105) is a certified pharmaceutical impurity reference standard with the molecular formula C17H20FN3O2S and a molecular weight of 349.42 g/mol.
The molecular framework of Vonoprazan Impurity 105 (C17H20FN3O2S) is characterized by a steroid core, an amide group, a sulfone group, a hydroxyl group, an ether linkage, fluorine substitution. In reversed-phase chromatography, its retention is governed primarily by the protonation state of its nitrogen-containing groups, which provides a practical basis for HPLC-UV/DAD or LC-MS method development. Nitrogen-containing functional groups confer excellent ionization efficiency in positive-ion electrospray (ESI) mode, making the compound well suited to LC-MS/MS analysis.
This reference standard supports related-substances testing and method development in line with ICH Q3A/Q3B guidance on impurity control, and is suitable for system suitability testing and forced-degradation studies.
Physical & Chemical Properties
| Molecular Formula | C17H20FN3O2S |
| Molecular Weight | 349.42 g/mol |
| Purity | >95% |
| Storage | Store at 2-8°C, protect from light, keep sealed and dry |
| Solubility (reference) | Soluble in DMSO, DMF, methanol |
| Stability | May oxidize slowly on prolonged air exposure; Light-sensitive; avoid direct strong light; Hygroscopic; reseal immediately after opening; Contains ester bond; hydrolyzes under strong alkaline conditions |
| Degree of Unsaturation (DBE) | 9.0 |
| UV Absorption | UV-absorbing |
| Structural Features | Aromatic ring present |
| Halogen Content | F-containing |
| Nitrogen Atoms | 3 |
| Sulfur Atoms | 1 |
Related Vonoprazan Standards
- Vonoprazan Impurity 106 (CAS CATO-C4X-1020106)
- Vonoprazan Impurity 107 (CAS CATO-C4X-1020107)
- Vonoprazan Impurity 108 (CAS CATO-C4X-1020108)
- Vonoprazan Impurity 109 (CAS CATO-C4X-1020109)
- Vonoprazan Impurity 277 (CAS CATO-C4X-1020277)
- Vonoprazan Impurity 278 (CAS CATO-C4X-1020278)
- Vonoprazan Impurity 279 (CAS CATO-C4X-1020279)
- Vonoprazan Impurity N20 (CAS 2416241-98-8)
Recommended Standards
- 1-N-Ethylgaramine Sulfate (CAS 864371-49-3)
- 3-[4-(benzyloxy)phenyl]-3-(2,5-dimethyl-1H-pyrrol-1-yl)propanoic acid 861207-99-0 KS-000033EF (CAS 861207-99-0)
- tert-butyl N-tert-butoxycarbonyl-N-(5-cyclobutylpyrimidin-2-yl)carbamate (CAS 2771023-81-3)
- tert-Butyl cis-3-amino-4-(benzyloxycarbonylamino)piperidine-1-carboxylate (CAS 766556-80-3)
- Argatroban Impurity 23 (CAS 1356847-56-7)
- Tryptophan EP Impurity L Lithium Salt (Mixture of Diastereomers) (CAS 287170-99-4 (Free Acid))
- Lifitegrast Impurity 9 (CAS 1289646-72-5)
- 3-(2-Ethylbutanamido)-2-methylbenzoic acid (CAS 890993-40-5)
- Ethyl(3-fluoro-5-methylphenyl)sulfane (CAS 1314938-01-6)
- 2-Methyl-1-(3-pyridyl)-1-propylamine (CAS 343270-47-3)
- N'-((1H-Benzo[d]imidazol-2-yl)methylene)formohydrazide (CAS 38202-63-0)
- n-(2,1,3-Benzoxadiazol-4-yl)acetamide (CAS 289650-01-7)
- Peramivir Impurity 71 (CAS 168683-02-1)
- Insulin Degludec Impurity 25 (CAS CATO-C4X-215725)
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