2,4-Bis(trifluoromethyl)chlorobenzene 1-chloro-2,4-bis(trifluoromethyl)benzene 1,3-bis(trifluoromethyl)-4-chlorobenzene 1-chloro-2,4-bis-(trifluoromethyl)benzene 2,4-bis-(trifluoromethyl)chlorobenzene 327-76-4 CAS 327-76-4

Purity 97%+In StockPharmaceutical Standards
CAS No.327-76-4
Molecular FormulaC8H3ClF6
Molecular Weight248.55 g/mol
CategoryPharmaceutical Standards / API Standards
AvailabilityIn Stock

Chemical Structure

2,4-Bis(trifluoromethyl)chlorobenzene
1-chloro-2,4-bis(trifluoromethyl)benzene
1,3-bis(trifluoromethyl)-4-chlorobenzene
1-chloro-2,4-bis-(trifluoromethyl)benzene
2,4-bis-(trifluoromethyl)chlorobenzene
327-76-4 CAS 327-76-4 chemical structure

Description

Compared with other compounds in its class, the molecular weight of 248.55 g/mol gives 2,4-Bis(trifluoromethyl)chlorobenzene 1-chloro-2,4-bis(trifluoromethyl)benzene 1,3-bis(trifluoromethyl)-4-chlorobenzene 1-chloro-2,4-bis-(trifluoromethyl)benzene 2,4-bis-(trifluoromethyl)chlorobenzene 327-76-4 distinctive chromatographic separation conditions and mass-spectrometry parameter settings.

2,4-Bis(trifluoromethyl)chlorobenzene 1-chloro-2,4-bis(trifluoromethyl)benzene 1,3-bis(trifluoromethyl)-4-chlorobenzene 1-chloro-2,4-bis-(trifluoromethyl)benzene 2,4-bis-(trifluoromethyl)chlorobenzene 327-76-4 (CAS 327-76-4), molecular formula C8H3ClF6 and molecular weight 248.55 g/mol, is a CATO reference standard with documented purity and traceability.

2,4-Bis(trifluoromethyl)chlorobenzene 1-chloro-2,4-bis(trifluoromethyl)benzene 1,3-bis(trifluoromethyl)-4-chlorobenzene 1-chloro-2,4-bis-(trifluoromethyl)benzene 2,4-bis-(trifluoromethyl)chlorobenzene 327-76-4 (C8H3ClF6) contains fluorine/chlorine substitution, an aromatic ring system. Halogen substitution raises its density and boiling point; these physicochemical properties determine the optimal preparation and storage of its standard solutions. Halogen substitution (F/Cl/Br/I) produces a distinctive isotope pattern in mass spectrometry, a valuable aid for qualitative confirmation.

This reference standard is suitable for quantitative analysis on major chromatographic platforms including HPLC, GC, LC-MS/MS, and GC-MS, serving as an external calibration standard or a system suitability test reference material.

As a certified reference material (CRM), 2,4-Bis(trifluoromethyl)chlorobenzene 1-chloro-2,4-bis(trifluoromethyl)benzene 1,3-bis(trifluoromethyl)-4-chlorobenzene 1-chloro-2,4-bis-(trifluoromethyl)benzene 2,4-bis-(trifluoromethyl)chlorobenzene 327-76-4 meets the metrological traceability requirements of ISO/IEC 17025 laboratories. Batch-to-batch consistency is monitored via control charts to guarantee comparable assigned values across lots.

Physical & Chemical Properties

Molecular FormulaC8H3ClF6
Molecular Weight248.55 g/mol
AppearanceOff-white to pale yellow crystalline powder. (slight halide-like odor, low volatility)
Purity97%+
StorageStore at room temperature, keep tightly closed to prevent evaporation
Solubility (reference)Soluble in methanol, acetonitrile, DMSO
StabilityMay oxidize slowly on prolonged air exposure
Degree of Unsaturation (DBE)4.0
UV AbsorptionUV-absorbing
Structural FeaturesAromatic ring present
CAS Registry Year (est.)1957
Halogen ContentF/Cl-containing

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