2-[1-(4-chlorophenyl)-3,5-dimethyl-1h-pyrazol-4-yl]acetic acid CAS 32701-92-1
| CAS No. | 32701-92-1 |
| Molecular Formula | C13H13ClN2O2 |
| Molecular Weight | 264.71 g/mol |
| Category | Pharmaceutical Standards / API Standards |
| Availability | In Stock |
Chemical Structure
Description
The occurrence of 2-[1-(4-chlorophenyl)-3,5-dimethyl-1h-pyrazol-4-yl]acetic acid is closely related to a nitrogen-containing heterocyclic scaffold, an amide group, a hydroxyl group, an ether linkage, chlorine substitution in its molecular formula, which determines its behaviour during synthesis, purification, or degradation.
CATO supplies 2-[1-(4-chlorophenyl)-3,5-dimethyl-1h-pyrazol-4-yl]acetic acid (CAS 32701-92-1), a certified reference material (molecular formula C13H13ClN2O2, MW 264.71 g/mol) for analytical method development and quality control.
The molecular framework of 2-[1-(4-chlorophenyl)-3,5-dimethyl-1h-pyrazol-4-yl]acetic acid (C13H13ClN2O2) is characterized by a nitrogen-containing heterocyclic scaffold, an amide group, a hydroxyl group, an ether linkage, chlorine substitution. In reversed-phase chromatography, its retention is governed primarily by its high hydrophobicity (logP), which provides a practical basis for HPLC-UV/DAD or LC-MS method development. Nitrogen-containing functional groups confer excellent ionization efficiency in positive-ion electrospray (ESI) mode, making the compound well suited to LC-MS/MS analysis.
This reference standard is suitable for quantitative analysis on major chromatographic platforms including HPLC, GC, LC-MS/MS, and GC-MS, serving as an external calibration standard or a system suitability test reference material.
As a certified reference material (CRM), 2-[1-(4-chlorophenyl)-3,5-dimethyl-1h-pyrazol-4-yl]acetic acid meets the metrological traceability requirements of ISO/IEC 17025 laboratories. Batch-to-batch consistency is monitored via control charts to guarantee comparable assigned values across lots.
Physical & Chemical Properties
| Molecular Formula | C13H13ClN2O2 |
| Molecular Weight | 264.71 g/mol |
| Appearance | Pale yellow to yellow crystalline powder. (slight halide-like odor) |
| Purity | 97%+ |
| Storage | Store at 2-8°C, protect from light, keep sealed and dry, keep tightly closed to prevent evaporation |
| Solubility (reference) | Soluble in DMSO, DMF, methanol |
| Stability | May oxidize slowly on prolonged air exposure; Light-sensitive; avoid direct strong light; Hygroscopic; reseal immediately after opening; Contains ester bond; hydrolyzes under strong alkaline conditions |
| Degree of Unsaturation (DBE) | 8.0 |
| UV Absorption | UV-absorbing |
| Structural Features | Aromatic ring present |
| CAS Registry Year (est.) | 1966 |
| Halogen Content | Cl-containing |
| Nitrogen Atoms | 2 |
Related chlorophenyl Standards
- 1-(2-Chlorophenyl)-5-(propan-2-yl)-1h-pyrazole-4-carboxylic acid (CAS 1002249-52-6)
- 1-(3-chlorophenyl)-5-isopropyl-1H-pyrazole-4-carboxylic acid (CAS 1004043-11-1)
- 3-(2-Chlorophenyl)-N-(5-methylisoxazol-3-yl)propanamide (CAS 1023480-58-1)
- 2-(4-chlorophenyl)-5-(propan-2-yl)-1H-imidazole-4-carboxylic acid (CAS 1156076-19-5)
- 1-[(4-chlorophenyl)methyl]-3,5-dimethyl-1h-pyrazole-4-carboxylic acid (CAS 1156433-10-1)
- Ethyl 2-(4-(4-Chlorophenyl)-1H-pyrazol-1-yl)acetate (CAS 1199773-60-8)
- 2-(3-Chlorophenyl)-5-(2-hydroxyethyl)-6-methylpyrimidin-4-ol (CAS 1239781-15-7)
- Ethyl 1-(4-chlorophenyl)-5-methyl-1H-pyrazole-3-carboxylate (CAS 126067-52-5)
Recommended Standards
- 2-(4-Chlorophenyl)-5-(2-hydroxyethyl)-6-methylpyrimidin-4(1H)-one (CAS 82019-55-4)
- 2-{6-chloro-2H,3H,4H-[1,3]oxazino[5,6-h]quinolin-3-yl}ethan-1-ol (CAS 380328-09-6)
- 2-(4-((2-Amino-6-chloropyrimidin-4-yl)amino)phenyl)ethanol (CAS 93003-21-5)
- 2-Chloro-5-(1,1-dimethylethyl)-1,3-dinitrobenzene (CAS 2213-81-2)
- 1-cyano-3-(methylmercurio)guanidine (CAS 502-39-6)
- 3-(2,5-Dichloropyrimidin-4-yl)pyrazolo[1,5-a]pyridine (CAS 1224709-13-0)
- Suc-Ala-Lys-Pro-Phe-pNA (L-1630.0050) (CAS 128802-74-4)
- 2-(2-Ethoxyethoxy)-N-(2-propoxybenzyl)aniline (CAS 1040691-24-4)
- N-(4-chloro-2-methylphenyl)-1-(phenylsulfonyl)-1H-pyrrolo[2,3-b]pyridine-2-carboxamide (CAS 477872-23-4)
- Lercanidipine Impurity 23 (CAS CATO-C4X-136423)
- 2,5-Dichloro-4-(difluoromethoxy)anisole (CAS 1803712-00-6)
- Ampicillin Impurity 83 (CAS CATO-C4X-144383)
- 3,5-Dibromo-1-{[3-chloro-4-(trifluoromethoxy)phenyl]methyl}-1h-1,2,4-triazole (CAS 1240573-75-4)
- Copper Peptide ·2 acetate salt (CAS 130120-57-9)
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