Dutasteride Impurity 4 CAS 328-93-8
| CAS No. | 328-93-8 |
| Molecular Formula | C8H5F6N |
| Molecular Weight | 229.12 g/mol |
| Category | Pharmacopoeial Impurity Standards / EP Impurities |
| Availability | In Stock |
Chemical Structure
Description
Compared with other compounds in its class, the molecular weight of 229.12 g/mol gives Dutasteride Impurity 4 distinctive chromatographic separation conditions and mass-spectrometry parameter settings.
CATO supplies Dutasteride Impurity 4 (CAS 328-93-8), a pharmacopoeial impurity reference standard (molecular formula C8H5F6N, MW 229.12 g/mol) used for the identification and quantification of trace impurities in APIs.
The molecular framework of Dutasteride Impurity 4 (C8H5F6N) is characterized by a nitrogen-containing heterocyclic scaffold, a nitrile group, fluorine substitution. In reversed-phase chromatography, its retention is governed primarily by the protonation state of its nitrogen-containing groups, which provides a practical basis for HPLC-UV/DAD or LC-MS method development. Halogen substitution (F/Cl/Br/I) produces a distinctive isotope pattern in mass spectrometry, a valuable aid for qualitative confirmation.
This reference standard supports related-substances testing and method development in line with ICH Q3A/Q3B guidance on impurity control, and is suitable for system suitability testing and forced-degradation studies.
CATO manufactures Dutasteride Impurity 4 under ISO 17034:2016 accreditation with dual CNAS and ANAB accreditation. Each batch is characterized by orthogonal methods and supplied with a full Certificate of Analysis (COA), ensuring metrological traceability.
Physical & Chemical Properties
| Molecular Formula | C8H5F6N |
| Molecular Weight | 229.12 g/mol |
| Appearance | Off-white to pale yellow crystalline powder. (slight halide-like odor, faint amine-like odor, low volatility) |
| Purity | >95% |
| Storage | Store at 2-8°C, protect from light, keep tightly closed to prevent evaporation |
| Solubility (reference) | Soluble in methanol, acetonitrile, DMSO |
| Stability | May oxidize slowly on prolonged air exposure; Light-sensitive; avoid direct strong light |
| Degree of Unsaturation (DBE) | 4.0 |
| UV Absorption | UV-absorbing |
| Structural Features | Aromatic ring present |
| CAS Registry Year (est.) | 1957 |
| Halogen Content | F-containing |
| Nitrogen Atoms | 1 |
Related Dutasteride Standards
- Dutasteride Impurity 19 (CAS 313-13-3)
- Dutasteride Impurity 20 (CAS 3822-20-6)
- Dutasteride Impurity 21 (CAS 2965-07-3)
- Dutasteride Impurity 21 (CAS 4640-41-9)
- Dutasteride Impurity 15 (CAS 84-58-2)
- Dutasteride impurity G (CAS 433-19-2)
- Dutasteride Impurity 22 (CAS 320-88-7)
- Dutasteride Impurity 22 (CAS 55982-15-5)
Recommended Standards
- N1-(4-Bromophenyl)-N1-methylethane-1,2-diamine (CAS 851265-79-7)
- ((2R,3S,4R)-5-Amino-3,4-dihydroxytetrahydrofuran-2-yl)methyl dihydrogen phosphate (CAS 14050-66-9)
- N-[(6-Bromopyridin-2-yl)methyl]propan-2-amine (CAS 478366-11-9)
- 4-chloro-2-methylsulfanyl-pyrimidine-5-carbonyl chloride (CAS 55084-66-7)
- Pregabalin Impurity 64 (CAS 2912-98-3)
- Cabazitaxel Impurity 10 (CAS CATO-C4X-111510)
- Mirogabalin Impurity 60 (CAS CATO-C4X-292460)
- 4-(4-Methoxyphenyl)-5-(pyridin-2-yl)-4h-1,2,4-triazole-3-thiol (CAS 63279-73-2)
- D-tert-Leucine (CAS 26782-71-8)
- 4-Butoxy-3-((methylsulfonyl)methyl)aniline (CAS 5819-63-6)
- Rimiterol HBr (CAS 31842-61-2)
- ((3S,4R)-4-(3,5-dimethoxyphenyl)pyrrolidin-3-yl)methanol hydrochloride (CAS 1217723-39-1)
- 5-fluoro-1-(methoxymethyl)-1H-indole (CAS 1488594-93-9)
- Semaglutide Impurity 75 (CAS CATO-C4X-2226175)
Why CATO?
- ISO 17034 accredited reference material producer (CNAS + ANAB dual accreditation)
- 130,000+ catalog items in stock, COA supplied with every batch
- Worldwide shipping with full export documentation (HS code guidance available)
- Technical support: +86 18665070610 / Nicole.chen@cato-chem.com