Dutasteride Impurity 15 CAS 84-58-2
| CAS No. | 84-58-2 |
| Molecular Formula | C8Cl2N2O2 |
| Molecular Weight | 227.00 g/mol |
| Category | Pharmacopoeial Impurity Standards / EP Impurities |
| Availability | In Stock |
Chemical Structure
Description
The occurrence of Dutasteride Impurity 15 is closely related to a nitrogen-containing heterocyclic scaffold, an amide group, a hydroxyl group, an ether linkage, chlorine substitution in its molecular formula, which determines its behaviour during synthesis, purification, or degradation.
As a process- or degradation-related impurity, Dutasteride Impurity 15 (CAS 84-58-2, C8Cl2N2O2) is essential for impurity profiling, related-substances testing, and forced-degradation studies in pharmaceutical development.
Structurally, Dutasteride Impurity 15 (C8Cl2N2O2) contains a nitrogen-containing heterocyclic scaffold, an amide group, a hydroxyl group, an ether linkage, chlorine substitution. The molecule exhibits a degree of unsaturation (DBE) of 9.0, corresponding to approximately 9 ring(s) or double-bond equivalent(s). With a molecular weight of 227.00 g/mol, it falls into the medium-molecular-weight range. Nitrogen-containing functional groups confer excellent ionization efficiency in positive-ion electrospray (ESI) mode, making the compound well suited to LC-MS/MS analysis.
This reference standard supports related-substances testing and method development in line with ICH Q3A/Q3B guidance on impurity control, and is suitable for system suitability testing and forced-degradation studies.
CATO manufactures Dutasteride Impurity 15 under ISO 17034:2016 accreditation with dual CNAS and ANAB accreditation. Each batch is characterized by orthogonal methods and supplied with a full Certificate of Analysis (COA), ensuring metrological traceability.
Physical & Chemical Properties
| Molecular Formula | C8Cl2N2O2 |
| Molecular Weight | 227.00 g/mol |
| Appearance | Pale yellow to yellow crystalline powder. (slight halide-like odor, faint amine-like odor, low volatility) |
| Purity | 97%+ |
| Storage | Store at 2-8°C, protect from light, keep sealed and dry, keep tightly closed to prevent evaporation |
| Solubility (reference) | Soluble in DMSO, DMF, methanol |
| Stability | May oxidize slowly on prolonged air exposure; Light-sensitive; avoid direct strong light; Hygroscopic; reseal immediately after opening; Contains ester bond; hydrolyzes under strong alkaline conditions |
| Degree of Unsaturation (DBE) | 9.0 |
| UV Absorption | UV-absorbing |
| Structural Features | Aromatic ring present |
| CAS Registry Year (est.) | 1957 |
| Halogen Content | Cl-containing |
| Nitrogen Atoms | 2 |
Related Dutasteride Standards
- Dutasteride Impurity 21 (CAS 4640-41-9)
- Dutasteride Impurity 19 (CAS 313-13-3)
- Dutasteride Impurity 20 (CAS 3822-20-6)
- Dutasteride Impurity 21 (CAS 2965-07-3)
- Dutasteride Impurity 4 (CAS 328-93-8)
- Dutasteride impurity G (CAS 433-19-2)
- Dutasteride Impurity 22 (CAS 320-88-7)
- Dutasteride Impurity 22 (CAS 55982-15-5)
Recommended Standards
- 3,4-Dichloro-5-oxo-2,5-dihydrofuran-2-yl methyl carbonate (CAS 67551-18-2)
- 3-Bromo-4-nitrobenzonitrile (CAS 102000-73-7)
- 2-Amino-3-(4-borono-2-fluorophenyl)propanoic acid (CAS 292050-22-7)
- 5-Bromo-6-cyanopyridine-3-carboxylic acid (CAS 1211537-28-8)
- Drotaverine Impurity 3 (CAS CATO-C4X-24353)
- Carbazochrome Impurity 22 (CAS CATO-C4X-229122)
- Rocuronium Impurity 34 (CAS CATO-C4X-124234)
- Lutetium(III) acetate hydrate (CAS 304675-59-0)
- B-(9,9-Diphenyl-9H-fluoren-2-yl)-boronic Acid (CAS 400607-31-0)
- 2,5,8-Trimethyl-7,8-dihydroimidazo[1,2-a]pyrazine-3,6(2H,5H)-dione (CAS 148599-74-0)
- 2-Chloro-N-(4-methoxyphenyl)-N,5-dimethylquinazolin-4-amine (CAS 827030-87-5)
- Tert-butyl 3-(1-nitroethylidene)azetidine-1-carboxylate (CAS 1679347-38-6)
- 2-[[2-[[2-(Acetyloxy)benzoyl]oxy]benzoyl]oxy]benzoic Acid 2-[(2-Carboxyphenoxy)carbonyl]phenyl Ester (CAS 85531-19-7)
- Gastric Inhibitory Polypeptide (human) (CAS 100040-31-1)
Why CATO?
- ISO 17034 accredited reference material producer (CNAS + ANAB dual accreditation)
- 130,000+ catalog items in stock, COA supplied with every batch
- Worldwide shipping with full export documentation (HS code guidance available)
- Technical support: +86 18665070610 / Nicole.chen@cato-chem.com