3-Amino-4-(3,4-dimethoxyphenyl)-N-(m-tolyl)-6-(p-tolyl)thieno[2,3-b]pyridine-2-carboxamide CAS 332155-26-7
| CAS No. | 332155-26-7 |
| Molecular Formula | C30H27N3O3S |
| Molecular Weight | 509.62 g/mol |
| Category | Pharmaceutical Standards / API Standards |
| Availability | In Stock |
Chemical Structure
Description
3-Amino-4-(3,4-dimethoxyphenyl)-N-(m-tolyl)-6-(p-tolyl)thieno[2,3-b]pyridine-2-carboxamide (CAS 332155-26-7) is a high-purity analytical reference standard with the molecular formula C30H27N3O3S and a molecular weight of 509.62 g/mol.
The molecular framework of 3-Amino-4-(3,4-dimethoxyphenyl)-N-(m-tolyl)-6-(p-tolyl)thieno[2,3-b]pyridine-2-carboxamide (C30H27N3O3S) is characterized by a steroid core, an amide group, a sulfone group, a hydroxyl group, an ether linkage. In reversed-phase chromatography, its retention is governed primarily by the protonation state of its nitrogen-containing groups, which provides a practical basis for HPLC-UV/DAD or LC-MS method development. Nitrogen-containing functional groups confer excellent ionization efficiency in positive-ion electrospray (ESI) mode, making the compound well suited to LC-MS/MS analysis.
This reference standard is suitable for quantitative analysis on major chromatographic platforms including HPLC, GC, LC-MS/MS, and GC-MS, serving as an external calibration standard or a system suitability test reference material.
As a certified reference material (CRM), 3-Amino-4-(3,4-dimethoxyphenyl)-N-(m-tolyl)-6-(p-tolyl)thieno[2,3-b]pyridine-2-carboxamide meets the metrological traceability requirements of ISO/IEC 17025 laboratories. Batch-to-batch consistency is monitored via control charts to guarantee comparable assigned values across lots.
Physical & Chemical Properties
| Molecular Formula | C30H27N3O3S |
| Molecular Weight | 509.62 g/mol |
| Purity | 97%+ |
| Storage | Store in a cool place (≤25°C), protect from light, keep sealed and dry |
| Solubility (reference) | Soluble in DMSO, DMF, methanol |
| Stability | May oxidize slowly on prolonged air exposure; Light-sensitive; avoid direct strong light; Hygroscopic; reseal immediately after opening |
| Degree of Unsaturation (DBE) | 19.0 |
| UV Absorption | UV-absorbing |
| Structural Features | Aromatic ring present |
| CAS Registry Year (est.) | 2025 |
| Nitrogen Atoms | 3 |
| Sulfur Atoms | 1 |
Related Amino Standards
- 3-Amino-4-(3,4-dimethoxyphenyl)-N-(2,4-dimethylphenyl)-6-phenylthieno[2,3-b]pyridine-2-carboxamide (CAS 332040-54-7)
- 3-Amino-4-(3,4-dimethoxyphenyl)-N-(2,6-dimethylphenyl)-6-phenylthieno[2,3-b]pyridine-2-carboxamide (CAS 332018-66-3)
- Ethyl 2-[3-amino-6-cyclopropyl-4-(trifluoromethyl)thieno[2,3-b]pyridine-2-amido]-4,5,6,7-tetrahydro-1-benzothiophene-3-carboxylate (CAS 626226-42-4)
- Ethyl 6-amino-5-cyano-2-(((3-cyano-6,7-dihydro-5H-cyclopenta[b]pyridin-2-yl)thio)methyl)-4-(5-nitrothiophen-2-yl)-4H-pyran-3-carboxylate (CAS 445390-92-1)
- N-(6-Amino-2,4-dioxo-1,3-dipropyl-1,2,3,4-tetrahydropyrimidin-5-yl)-3,5-dichloro-2-(2,2,2-trifluoroacetamido)benzamide (CAS 154623-75-3)
- 3-Amino-4-(benzo[d][1,3]dioxol-5-yl)-N-(4-nitrophenyl)-6-phenylthieno[2,3-b]pyridine-2-carboxamide (CAS 332053-71-1)
- 3-Amino-N-(4-(N-(4,6-dimethylpyrimidin-2-yl)sulfamoyl)phenyl)-5,6,7,8-tetrahydrothieno[2,3-b]quinoline-2-carboxamide (CAS 400863-72-1)
- 3-Amino-N-(5-((2-chlorobenzyl)thio)-1,3,4-thiadiazol-2(3H)-ylidene)-6-(pyridin-4-yl)thieno[2,3-b]pyridine-2-carboxamide (CAS 445267-60-7)
Recommended Standards
- N-(3-Fluoro-4-methylphenyl)-2-((3-(4-methoxyphenyl)-4-oxo-3,4,5,6,7,8-hexahydrobenzo[4,5]thieno[2,3-d]pyrimidin-2-yl)thio)acetamide (CAS 477330-68-0)
- Argatroban Impurity 19 (CAS 2423016-01-5)
- 2-((3-Cyano-4-(3,4-dimethoxyphenyl)-6-phenylpyridin-2-yl)thio)-N-(o-tolyl)propanamide (CAS 337499-33-9)
- 3,4-Dihydro-6-[[4-[[[3-(methylsulfonyl)phenyl]methyl]amino]-5-(trifluoromethyl)-2-pyrimidinyl]amino]-2(1H)-quinolinone 6-[(4-((3-(Methanesulfonyl)benzyl)amino)-5-trifluoromethylpyrimidin-2-yl)amino]-3,4-dihydro-1H-quinolin-2-one 6-[4-(3-Methanesulfonyl-benzylamino)-5-trifluoromethyl-pyrimidin-2-ylamino]-3,4-dihydro-1H-quinolin-2-one 869288-64-2 PF 573228 PF-228 PF-573228 (CAS 869288-64-2)
- 2-((4-Ethyl-5-propyl-4H-1,2,4-triazol-3-yl)thio)acetic acid (CAS 603071-16-5)
- (3-Bromo-5-methoxy-4-((3-methylbenzyl)oxy)phenyl)methanol (CAS 752991-26-7)
- 1-(3-Fluoro-4-methoxyphenyl)propan-2-ol (CAS 1021927-95-6)
- Argatroban Impurity 29 (CAS 74863-82-4)
- (S)-1-Boc-N-methoxy-N-methylpiperidine-3-carboxamide (CAS 1008562-93-3)
- 2-[1-(Methoxymethyl)cyclopropyl]acetic Acid (CAS 1369161-15-8)
- 2,3,3-Triphenylacrylonitrile (CAS 7136-23-4)
- Pyridine-4-sulfonic acid cyclopropylamide (CAS 1823336-92-0)
- 3-Acetyl-5-iodobenzoic acid (CAS 1393557-43-1)
- D-[Asp]9-Semaglutide (CAS CATO-CPTD788631)
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