Voriconazole Impurity 8 CAS 83603-04-7
| CAS No. | 83603-04-7 |
| Molecular Formula | C11H18O4S |
| Molecular Weight | 246.32 g/mol |
| Category | Pharmacopoeial Impurity Standards / EP Impurities |
| Availability | In Stock |
Chemical Structure
Description
Voriconazole Impurity 8 (C11H18O4S) contains a sulfone group, a carboxylic acid group, a hydroxyl group, an ether linkage. It is notably hygroscopic, its high carbon-to-hydrogen ratio confers good lipid solubility, the carboxyl group imparts weak acidity; these physicochemical properties determine the optimal preparation and storage of its standard solutions. The high carbon-to-hydrogen ratio imparts good lipophilicity, allowing liquid-liquid extraction with non-polar solvents such as n-hexane or ethyl acetate.
CATO supplies Voriconazole Impurity 8 (CAS 83603-04-7), a pharmacopoeial impurity reference standard (molecular formula C11H18O4S, MW 246.32 g/mol) used for the identification and quantification of trace impurities in APIs.
Recommended for quantitative analysis by HPLC, GC, LC-MS/MS, or GC-MS as an external calibration standard; it can also be used for spiked-recovery experiments, LOD/LOQ determination, and LC-MS/MS multiple-reaction-monitoring (MRM) calibration.
As a certified reference material (CRM), Voriconazole Impurity 8 meets the metrological traceability requirements of ISO/IEC 17025 laboratories. Batch-to-batch consistency is monitored via control charts to guarantee comparable assigned values across lots.
Physical & Chemical Properties
| Molecular Formula | C11H18O4S |
| Molecular Weight | 246.32 g/mol |
| Purity | >95% |
| Storage | Store in a cool place (≤25°C), keep sealed and dry |
| Solubility (reference) | Soluble in methanol, ethanol, DMSO |
| Stability | May oxidize slowly on prolonged air exposure; Hygroscopic; reseal immediately after opening |
| Degree of Unsaturation (DBE) | 3.0 |
| UV Absorption | UV-absorbing |
| CAS Registry Year (est.) | 1980 |
| Sulfur Atoms | 1 |
Related Voriconazole Standards
- Voriconazole Impurity 3 (CAS 188416-28-6)
- Voriconazole Impurity 72 (CAS CATO-C4X-136672)
- Voriconazole Impurity 86 (CAS CATO-C4X-136686)
- Voriconazole EP Impurity E(Voriconazole Related Compound F) (CAS 5872-08-2)
- Voriconazole EP Impurity E (1R)-Isomer (CAS 35963-20-3)
- Voriconazole Impurity 43 (CAS 154335-57-6)
- Voriconazole Impurity 7 (CAS CATO-C4X-13667)
- Voriconazole Impurity 82 (CAS CATO-C4X-136682)
Recommended Standards
- 4,4-Sulfonylbis(methylbenzene) (CAS 599-66-6)
- Agomelatine-D3 (CAS 107389-38-0)
- 6D623JMP3R 556-91-2 Aluminum tert-butoxide Aluminium tri-tert-butanolate tert-Butyl alcohol, aluminum salt (8CI) 2-Propanol, 2-methyl-, aluminum salt (3:1) 2-Propanol, 2-methyl-, aluminum salt Aluminum tert-butanolate Aluminum tert-butylate Aluminum tri-tert-butoxide Aluminum, tri-tert-butoxy- Aluminum, tris-tert-butoxy- EINECS 209-146-1 NSC 4648 Tri-tert-butoxyaluminum UNII-6D623JMP3R (CAS 556-91-2)
- Biotin-d2 (CAS 1217481-41-8)
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- Methyl 3-azabicyclo[3.3.1]Nonane-9-carboxylate hydrochloride (CAS 1824600-23-8)
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- 2-(((1-(Benzylsulfonyl)piperidin-4-yl)methyl)thio)-4-methylthiazole (CAS 1428357-46-3)
- Tert-butyl 3-amino-4-(hydroxymethyl)piperidine-1-carboxylate (CAS 1782754-25-9)
- 4-Nitrophenyl sulfate potassium salt (CAS 6217-68-1)
- (2-Bromo-6-propylpyridin-4-yl)boronic acid (CAS 2225154-52-7)
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Why CATO?
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- 130,000+ catalog items in stock, COA supplied with every batch
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