2-((2-(3,4-Dihydroquinolin-1(2H)-yl)-2-oxoethyl)thio)-6-(4-ethoxyphenyl)-4-phenylnicotinonitrile CAS 332375-63-0
| CAS No. | 332375-63-0 |
| Molecular Formula | C31H27N3O2S |
| Molecular Weight | 505.63 g/mol |
| Category | Pharmaceutical Standards / API Standards |
| Availability | In Stock |
Chemical Structure
Description
Under current pharmacopoeial and regulatory frameworks, quality-control requirements for this class of reference material explicitly involve the control of targets including 2-((2-(3,4-Dihydroquinolin-1(2H)-yl)-2-oxoethyl)thio)-6-(4-ethoxyphenyl)-4-phenylnicotinonitrile.
CATO supplies 2-((2-(3,4-Dihydroquinolin-1(2H)-yl)-2-oxoethyl)thio)-6-(4-ethoxyphenyl)-4-phenylnicotinonitrile (CAS 332375-63-0), a certified reference material (molecular formula C31H27N3O2S, MW 505.63 g/mol) for analytical method development and quality control.
Based on its molecular formula C31H27N3O2S, 2-((2-(3,4-Dihydroquinolin-1(2H)-yl)-2-oxoethyl)thio)-6-(4-ethoxyphenyl)-4-phenylnicotinonitrile contains a nitrogen-containing heterocyclic scaffold, an amide group, a sulfone group, a hydroxyl group, an ether linkage; these features give the compound characteristic absorption bands in UV spectroscopy. The molecular weight of 505.63 g/mol is directly relevant to the identification of the molecular ion in mass spectrometry. Nitrogen-containing functional groups confer excellent ionization efficiency in positive-ion electrospray (ESI) mode, making the compound well suited to LC-MS/MS analysis.
This reference standard is suitable for quantitative analysis on major chromatographic platforms including HPLC, GC, LC-MS/MS, and GC-MS, serving as an external calibration standard or a system suitability test reference material.
The assigned purity is verified by mass-balance and quantitative NMR (qNMR) approaches, with the expanded uncertainty reported at a 95% confidence level (k=2). Batch homogeneity and stability are independently assessed for every lot.
Physical & Chemical Properties
| Molecular Formula | C31H27N3O2S |
| Molecular Weight | 505.63 g/mol |
| Purity | 97%+ |
| Storage | Store in a cool place (≤25°C), protect from light, keep sealed and dry |
| Solubility (reference) | Soluble in DMSO, DMF, methanol |
| Stability | May oxidize slowly on prolonged air exposure; Light-sensitive; avoid direct strong light; Hygroscopic; reseal immediately after opening |
| Degree of Unsaturation (DBE) | 20.0 |
| UV Absorption | UV-absorbing |
| Structural Features | Aromatic ring present |
| CAS Registry Year (est.) | 2025 |
| Nitrogen Atoms | 3 |
| Sulfur Atoms | 1 |
Related Dihydroquinolin Standards
- 2-((2-(3,4-Dihydroquinolin-1(2H)-yl)-2-oxoethyl)thio)-4-(4-methoxyphenyl)-6-(p-tolyl)nicotinonitrile (CAS 337498-13-2)
- 1-(3,4-Dihydroquinolin-1(2H)-yl)-2-((4-(2-ethoxyphenyl)-5-(pyridin-3-yl)-4H-1,2,4-triazol-3-yl)thio)ethan-1-one (CAS 851274-39-0)
- 1-(3,4-Dihydroquinolin-1(2H)-yl)-2-((5-(phenoxymethyl)-4-phenyl-4H-1,2,4-triazol-3-yl)thio)ethan-1-one (CAS 483284-59-9)
- 2-((2-(3,4-Dihydroquinolin-1(2H)-yl)-2-oxoethyl)thio)-3-methyl-7-phenylthieno[3,2-d]pyrimidin-4(3H)-one (CAS 1040632-71-0)
- 2-((6-((3,4-Dihydroquinolin-1(2H)-yl)methyl)-4-oxo-4H-pyran-3-yl)oxy)-N-(2-ethoxyphenyl)acetamide (CAS 898456-24-1)
- 2-((3,4-Dihydroquinolin-1(2H)-yl)methylene)malononitrile (CAS 6687-85-0)
- 1-(3,4-Dihydroquinolin-1(2H)-yl)-2-((4-phenyl-5-(pyridin-4-yl)-4H-1,2,4-triazol-3-yl)thio)ethanone (CAS 332376-19-9)
- 2-((6-((3,4-Dihydroquinolin-1(2H)-yl)methyl)-4-oxo-4H-pyran-3-yl)oxy)-N-phenylacetamide (CAS 898455-72-6)
Recommended Standards
- 3-(4-((6-(5-((3AS,4S,6aR)-2-oxohexahydro-1H-thieno[3,4-d]imidazol-4-yl)pentanamido)hexanoyl)oxy)phenyl)propanoic acid (CAS 83592-10-3)
- (1R)-(2'-(Dimethylamino)-5,5',6,6',7,7',8,8'-octahydro-[1,1'-binaphthalen]-2-yl)diphenylphosphine oxide (CAS 328074-68-6)
- 756525-97-0 15-Biotinamino-4,7,10,13-tetraoxa-pentadecanoyl hydrazide MFCD09952658 (CAS 756525-97-0)
- Amprenavir (CAS 161814-49-9)
- 2-((Pyridin-3-ylmethyl)amino)isonicotinic acid (CAS 1036599-81-1)
- 2',4'-Dihydroxyhexanophenone (CAS 3144-54-5)
- (1R,4r)-4-(6-fluoroquinolin-4-yl)cyclohexyl methanesulfonate (CAS 1923846-50-7)
- 2-(Aminomethyl)-1-(thiophen-2-yl)pentan-1-ol (CAS 1521361-47-6)
- Indolin-1-yl(3-iodophenyl)methanone (CAS 349118-10-1)
- (s)-2-Amino-2-(4-chloro-3-methylphenyl)ethan-1-ol (CAS 1213038-73-3)
- 5-Bromo-6-fluoro-1-benzofuran (CAS 1427417-54-6)
- Tert-butyl (R)-(2-(piperidin-2-yl)ethyl)carbamate (CAS 1821791-75-6)
- 1-(2-(Trifluoromethyl)pyridin-3-yl)cyclopropane-1-carbonitrile (CAS 1427012-75-6)
- FMRF-Like Neuropeptide (CAS 121801-61-4)
Why CATO?
- ISO 17034 accredited reference material producer (CNAS + ANAB dual accreditation)
- 130,000+ catalog items in stock, COA supplied with every batch
- Worldwide shipping with full export documentation (HS code guidance available)
- Technical support: +86 18665070610 / Nicole.chen@cato-chem.com