2-((2-(3,4-Dihydroquinolin-1(2H)-yl)-2-oxoethyl)thio)-4-(4-methoxyphenyl)-6-(p-tolyl)nicotinonitrile CAS 337498-13-2
| CAS No. | 337498-13-2 |
| Molecular Formula | C31H27N3O2S |
| Molecular Weight | 505.63 g/mol |
| Category | Pharmaceutical Standards / API Standards |
| Availability | In Stock |
Chemical Structure
Description
The occurrence of 2-((2-(3,4-Dihydroquinolin-1(2H)-yl)-2-oxoethyl)thio)-4-(4-methoxyphenyl)-6-(p-tolyl)nicotinonitrile is closely related to a nitrogen-containing heterocyclic scaffold, an amide group, a sulfone group, a hydroxyl group, an ether linkage in its molecular formula, which determines its behaviour during synthesis, purification, or degradation.
CATO supplies 2-((2-(3,4-Dihydroquinolin-1(2H)-yl)-2-oxoethyl)thio)-4-(4-methoxyphenyl)-6-(p-tolyl)nicotinonitrile (CAS 337498-13-2), a certified reference material (molecular formula C31H27N3O2S, MW 505.63 g/mol) for analytical method development and quality control.
Owing to a nitrogen-containing heterocyclic scaffold, an amide group, a sulfone group, a hydroxyl group, an ether linkage, 2-((2-(3,4-Dihydroquinolin-1(2H)-yl)-2-oxoethyl)thio)-4-(4-methoxyphenyl)-6-(p-tolyl)nicotinonitrile is typically pale yellow to yellow crystalline powder. Its solid-state physicochemical attributes — including a molecular weight of 505.63 g/mol — guide the selection of appropriate sample preparation and analytical techniques. The aromatic system may exhibit native fluorescence, enabling detection with a fluorescence detector (FLD).
This reference standard is suitable for quantitative analysis on major chromatographic platforms including HPLC, GC, LC-MS/MS, and GC-MS, serving as an external calibration standard or a system suitability test reference material.
CATO manufactures 2-((2-(3,4-Dihydroquinolin-1(2H)-yl)-2-oxoethyl)thio)-4-(4-methoxyphenyl)-6-(p-tolyl)nicotinonitrile under ISO 17034:2016 accreditation with dual CNAS and ANAB accreditation. Each batch is characterized by orthogonal methods and supplied with a full Certificate of Analysis (COA), ensuring metrological traceability.
Physical & Chemical Properties
| Molecular Formula | C31H27N3O2S |
| Molecular Weight | 505.63 g/mol |
| Purity | 97%+ |
| Storage | Store in a cool place (≤25°C), protect from light, keep sealed and dry |
| Solubility (reference) | Soluble in DMSO, DMF, methanol |
| Stability | May oxidize slowly on prolonged air exposure; Light-sensitive; avoid direct strong light; Hygroscopic; reseal immediately after opening |
| Degree of Unsaturation (DBE) | 20.0 |
| UV Absorption | UV-absorbing |
| Structural Features | Aromatic ring present |
| CAS Registry Year (est.) | 2025 |
| Nitrogen Atoms | 3 |
| Sulfur Atoms | 1 |
Related Dihydroquinolin Standards
- 2-((2-(3,4-Dihydroquinolin-1(2H)-yl)-2-oxoethyl)thio)-6-(4-ethoxyphenyl)-4-phenylnicotinonitrile (CAS 332375-63-0)
- 1-(3,4-Dihydroquinolin-1(2H)-yl)-2-((4-(2-ethoxyphenyl)-5-(pyridin-3-yl)-4H-1,2,4-triazol-3-yl)thio)ethan-1-one (CAS 851274-39-0)
- 1-(3,4-Dihydroquinolin-1(2H)-yl)-2-((5-(phenoxymethyl)-4-phenyl-4H-1,2,4-triazol-3-yl)thio)ethan-1-one (CAS 483284-59-9)
- 2-((2-(3,4-Dihydroquinolin-1(2H)-yl)-2-oxoethyl)thio)-3-methyl-7-phenylthieno[3,2-d]pyrimidin-4(3H)-one (CAS 1040632-71-0)
- 2-((6-((3,4-Dihydroquinolin-1(2H)-yl)methyl)-4-oxo-4H-pyran-3-yl)oxy)-N-(2-ethoxyphenyl)acetamide (CAS 898456-24-1)
- 2-((3,4-Dihydroquinolin-1(2H)-yl)methylene)malononitrile (CAS 6687-85-0)
- 1-(3,4-Dihydroquinolin-1(2H)-yl)-2-((4-phenyl-5-(pyridin-4-yl)-4H-1,2,4-triazol-3-yl)thio)ethanone (CAS 332376-19-9)
- 2-((6-((3,4-Dihydroquinolin-1(2H)-yl)methyl)-4-oxo-4H-pyran-3-yl)oxy)-N-phenylacetamide (CAS 898455-72-6)
Recommended Standards
- (1R)-(2'-(Dimethylamino)-5,5',6,6',7,7',8,8'-octahydro-[1,1'-binaphthalen]-2-yl)diphenylphosphine oxide (CAS 328074-68-6)
- Amprenavir (CAS 161814-49-9)
- 3-(4-((6-(5-((3AS,4S,6aR)-2-oxohexahydro-1H-thieno[3,4-d]imidazol-4-yl)pentanamido)hexanoyl)oxy)phenyl)propanoic acid (CAS 83592-10-3)
- Tolafentrine (CAS 139308-65-9)
- 4-Methyl-3,4-dihydro-2H-1,4-benzoxazine-6-carboxylic acid hydrochloride (CAS 1890285-66-1)
- (4R,5S)-4-Ethyl-5-methyl-4,5-dihydrooxazol-2-amine (CAS 599206-77-6)
- Methyl 4-(tert-butyl)-2-ethoxybenzoate (CAS 870007-39-9)
- 1-(3-Iodobenzyl)piperidine (CAS 859850-87-6)
- TCBT 52 (CAS 121107-65-1)
- 4-(Methylsulfonyl)benzylamine (CAS 4393-16-2)
- 5'-(3-Formylphenyl)-[1,1':3',1''-terphenyl]-3,3''-dicarbaldehyde (CAS 1395348-26-1)
- Methyl 5-acetamido-4-7-8-9-tetra-O-acetyl-2-6-anhydro-3-5-dideoxy-D-glycero-D-galacto-non-2-enonate (CAS 73960-72-2)
- N-(2-((4-chlorophenyl)thio)ethyl)-3-(phenylthio)propanamide (CAS 337923-21-4)
- Peptide 6A (H-6905.0005) (CAS 73549-32-3)
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