Vonoprazan Impurity 194 CAS 33263-44-4
| CAS No. | 33263-44-4 |
| Molecular Formula | C5H3Cl2NO2S |
| Molecular Weight | 212.05 g/mol |
| Category | Pharmacopoeial Impurity Standards / EP Impurities |
| Availability | In Stock |
Chemical Structure
Description
CATO supplies Vonoprazan Impurity 194 (CAS 33263-44-4), a pharmacopoeial impurity reference standard (molecular formula C5H3Cl2NO2S, MW 212.05 g/mol) used for the identification and quantification of trace impurities in APIs.
Owing to an amide group, a sulfone group, a carboxylic acid group, a hydroxyl group, an ether linkage, chlorine substitution, Vonoprazan Impurity 194 is typically off-white to pale yellow crystalline powder. Its solid-state physicochemical attributes — including a molecular weight of 212.05 g/mol — guide the selection of appropriate sample preparation and analytical techniques. Nitrogen-containing functional groups confer excellent ionization efficiency in positive-ion electrospray (ESI) mode, making the compound well suited to LC-MS/MS analysis.
Recommended for quantitative analysis by HPLC, GC, LC-MS/MS, or GC-MS as an external calibration standard; it can also be used for spiked-recovery experiments, LOD/LOQ determination, and LC-MS/MS multiple-reaction-monitoring (MRM) calibration.
The assigned purity is verified by mass-balance and quantitative NMR (qNMR) approaches, with the expanded uncertainty reported at a 95% confidence level (k=2). Batch homogeneity and stability are independently assessed for every lot.
Physical & Chemical Properties
| Molecular Formula | C5H3Cl2NO2S |
| Molecular Weight | 212.05 g/mol |
| Purity | >95% |
| Storage | Store at 2-8°C, protect from light, keep tightly closed to prevent evaporation |
| Solubility (reference) | Soluble in methanol, acetonitrile, DMSO, water (slightly soluble) |
| Stability | May oxidize slowly on prolonged air exposure; Light-sensitive; avoid direct strong light; Contains ester bond; hydrolyzes under strong alkaline conditions |
| Degree of Unsaturation (DBE) | 4.0 |
| UV Absorption | UV-absorbing |
| CAS Registry Year (est.) | 1966 |
| Halogen Content | Cl-containing |
| Nitrogen Atoms | 1 |
| Sulfur Atoms | 1 |
Related Vonoprazan Standards
- Vonoprazan Fumarate Impurity 71 (CAS 1060802-18-7)
- Vonoprazan Impurity 210 (CAS CATO-C4X-1020210)
- Vonoprazan Impurity 137 (CAS CATO-C4X-1020137)
- Vonoprazan Impuirty 128 (CAS 928324-50-9)
- Vonoprazan Fumarate Impurity 88 (CAS 655-15-2)
- Vonoprazan Fumarate Impurity 96 (CAS 403-29-2)
- Vonoprazan Impurity 307 (CAS CATO-C4X-1020307)
- Vonoprazan Impurity 142 (CAS CATO-C4X-1020142)
Recommended Standards
- Methyl 3,4-dichloroisothiazole-5-carboxylate (CAS 352010-56-1)
- Methyl 2,4-dichlorothiazole-5-carboxylate (CAS 861708-66-9)
- 6-(bromomethyl)-6-fluoro-1,4-oxazepane (CAS 2680760-04-5)
- cis-2-(4,4,5,5-tetramethyl-1,3,2-dioxaborolan-2-yl)cyclopropanecarboxylic acid (CAS 2382719-63-1)
- Ertapenem Impurity 7 (CAS CATO-C4X-16337)
- Sunitinib Impurity 18 (CAS 326914-17-4)
- Glycopyrronium Bromide impurity 15 (CAS 1404453-67-3)
- Ethyl 3-(1,3-dioxan-2-yl)benzoylformate (CAS 951888-31-6)
- 3-bromo-4-fluoro-1H-pyrazole (CAS 1621526-49-5)
- 2-((5-Benzyl-4-methyl-4H-1,2,4-triazol-3-yl)thio)-N-(3-cyano-4,5-dimethylthiophen-2-yl)acetamide (CAS 332935-91-8)
- Tris[di(4-acetoxybenzylidene)acetone]dipalladium(0) di(4-acetoxybenzylidene)acetone adduct (CAS 1196118-15-6)
- 2,4-Dichloro-5,7-dihydrofuro[3,4-b]pyridine (CAS 1086321-79-0)
- 4',5'-Dihydrospiro[piperidine-4,7'-thieno[2,3-c]pyran], trifluoroacetic acid (CAS 1307248-40-3)
- Semaglutide Impurity 10 (CAS CATO-C4X-222610)
Why CATO?
- ISO 17034 accredited reference material producer (CNAS + ANAB dual accreditation)
- 130,000+ catalog items in stock, COA supplied with every batch
- Worldwide shipping with full export documentation (HS code guidance available)
- Technical support: +86 18665070610 / Nicole.chen@cato-chem.com