2-((3-Cyano-6-(4-methoxyphenyl)-4-phenylpyridin-2-yl)thio)-N-(3-nitrophenyl)acetamide CAS 333341-63-2
| CAS No. | 333341-63-2 |
| Molecular Formula | C27H20N4O4S |
| Molecular Weight | 496.54 g/mol |
| Category | Pharmaceutical Standards / API Standards |
| Availability | In Stock |
Chemical Structure
Description
2-((3-Cyano-6-(4-methoxyphenyl)-4-phenylpyridin-2-yl)thio)-N-(3-nitrophenyl)acetamide (CAS 333341-63-2), molecular formula C27H20N4O4S and molecular weight 496.54 g/mol, is a CATO reference standard with documented purity and traceability.
2-((3-Cyano-6-(4-methoxyphenyl)-4-phenylpyridin-2-yl)thio)-N-(3-nitrophenyl)acetamide (C27H20N4O4S) contains a steroid core, an amide group, a sulfone group, a hydroxyl group, an ether linkage. It is notably hygroscopic, the carboxyl group imparts weak acidity; these physicochemical properties determine the optimal preparation and storage of its standard solutions. The aromatic system may exhibit native fluorescence, enabling detection with a fluorescence detector (FLD).
This reference standard is suitable for quantitative analysis on major chromatographic platforms including HPLC, GC, LC-MS/MS, and GC-MS, serving as an external calibration standard or a system suitability test reference material.
The assigned purity is verified by mass-balance and quantitative NMR (qNMR) approaches, with the expanded uncertainty reported at a 95% confidence level (k=2). Batch homogeneity and stability are independently assessed for every lot.
Physical & Chemical Properties
| Molecular Formula | C27H20N4O4S |
| Molecular Weight | 496.54 g/mol |
| Purity | 97%+ |
| Storage | Store in a cool place (≤25°C), protect from light, keep sealed and dry |
| Solubility (reference) | Soluble in DMSO, DMF, methanol |
| Stability | May oxidize slowly on prolonged air exposure; Light-sensitive; avoid direct strong light; Hygroscopic; reseal immediately after opening |
| Degree of Unsaturation (DBE) | 20.0 |
| UV Absorption | UV-absorbing |
| Structural Features | Aromatic ring present |
| CAS Registry Year (est.) | 2025 |
| Nitrogen Atoms | 4 |
| Sulfur Atoms | 1 |
Related Cyano Standards
- 2-((3-Cyano-4-(4-methoxyphenyl)-6-phenylpyridin-2-yl)thio)-N-(2-nitrophenyl)acetamide (CAS 332053-80-2)
- 2-((3-Cyano-4-(4-methoxyphenyl)-6-phenylpyridin-2-yl)thio)-N-(3-nitrophenyl)acetamide (CAS 332018-67-4)
- 2-((3-Cyano-4-(4-methoxyphenyl)-6-phenylpyridin-2-yl)thio)-N-(4-nitrophenyl)acetamide (CAS 332018-70-9)
- 2-((3-Cyano-4,6-diphenylpyridin-2-yl)thio)-N-(4-methoxy-2-nitrophenyl)acetamide (CAS 336180-37-1)
- 2-((3-Cyano-6-(4-methoxyphenyl)-4-phenylpyridin-2-yl)thio)-N-(4-nitrophenyl)acetamide (CAS 333341-73-4)
- 2-((3-Cyano-4-(3,4-dimethoxyphenyl)-6-(p-tolyl)pyridin-2-yl)thio)-N-phenylacetamide (CAS 332126-94-0)
- 2-((3-Cyano-4-(3,4-dimethoxyphenyl)-6-phenylpyridin-2-yl)thio)-N-(p-tolyl)acetamide (CAS 444152-24-3)
- 2-((3-Cyano-4-(4-methoxyphenyl)-6-(p-tolyl)pyridin-2-yl)thio)-N-(2-methoxyphenyl)acetamide (CAS 337498-29-0)
Recommended Standards
- 3-Amino-4-(4-methoxyphenyl)-N-(2-nitrophenyl)-6-phenylthieno[2,3-b]pyridine-2-carboxamide (CAS 332053-72-2)
- Ethyl 6-amino-5-cyano-2-[({5-cyano-[2,4'-bipyridine]-6-yl}sulfanyl)methyl]-4-(pyridin-3-yl)-4H-pyran-3-carboxylate (CAS 313380-23-3)
- Fluocinolone Acetonide Impurity 23 (CAS CATO-C4X-238123)
- 2-((5-((6H-Indolo[2,3-b]quinoxalin-6-yl)methyl)-4-(4-methoxyphenyl)-4H-1,2,4-triazol-3-yl)thio)acetic acid (CAS 116989-77-6)
- Butyl 2,4-dichloro-6-methylnicotinate (CAS 1779124-03-6)
- (R)-3-amino-3-(4-bromophenyl)propanenitrile (CAS 1212985-72-2)
- 1-(4-Aminophenyl)-3-(1H-indol-3-yl)prop-2-en-1-one (CAS 1005931-04-3)
- Tetraethylene glycol (CAS 112-60-7)
- N-butyl-4,5,6,7-tetrahydro-1,3-benzothiazol-6-amine (CAS 70590-67-9)
- (5Z)-5-[(5-Chloro-1,3-dimethyl-1H-pyrazol-4-yl)methylidene]-1,3-thiazolidine-2,4-dione (CAS 956244-33-0)
- 3-Isopropylpyrazin-2-amine (CAS 1483114-41-5)
- 3-(4-Methylpyridin-3-yl)propanal (CAS 1502958-02-2)
- 4-(2-Methoxyphenyl)-2,4-dioxobutanoic acid (CAS 77664-74-5)
- Tirzepatide Impurity 57 (CAS CATO-C4X-324057)
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