6-chloro-2-fluoro-3-nitro-pyridine CAS 333998-11-1
| CAS No. | 333998-11-1 |
| Molecular Formula | C5H8ClFN2O2 |
| Molecular Weight | 182.58 g/mol |
| Category | Pharmaceutical Standards / API Standards |
| Availability | In Stock |
Chemical Structure
Description
This reference standard is suitable for quantitative analysis on major chromatographic platforms including HPLC, GC, LC-MS/MS, and GC-MS, serving as an external calibration standard or a system suitability test reference material.
CATO supplies 6-chloro-2-fluoro-3-nitro-pyridine (CAS 333998-11-1), a certified reference material (molecular formula C5H8ClFN2O2, MW 182.58 g/mol) for analytical method development and quality control.
Owing to an amide group, a carboxylic acid group, a hydroxyl group, an ether linkage, fluorine/chlorine substitution, 6-chloro-2-fluoro-3-nitro-pyridine is typically white to off-white crystalline powder. Its solid-state physicochemical attributes — including a molecular weight of 182.58 g/mol — guide the selection of appropriate sample preparation and analytical techniques. Nitrogen-containing functional groups confer excellent ionization efficiency in positive-ion electrospray (ESI) mode, making the compound well suited to LC-MS/MS analysis.
CATO manufactures 6-chloro-2-fluoro-3-nitro-pyridine under ISO 17034:2016 accreditation with dual CNAS and ANAB accreditation. Each batch is characterized by orthogonal methods and supplied with a full Certificate of Analysis (COA), ensuring metrological traceability.
Physical & Chemical Properties
| Molecular Formula | C5H8ClFN2O2 |
| Molecular Weight | 182.58 g/mol |
| Purity | 97%+ |
| Storage | Store at 2-8°C, protect from light, keep sealed and dry, keep tightly closed to prevent evaporation |
| Solubility (reference) | Soluble in DMSO, DMF, methanol |
| Stability | Light-sensitive; avoid direct strong light; Hygroscopic; reseal immediately after opening; Contains ester bond; hydrolyzes under strong alkaline conditions |
| Degree of Unsaturation (DBE) | 2.0 |
| CAS Registry Year (est.) | 2025 |
| Halogen Content | F/Cl-containing |
| Nitrogen Atoms | 2 |
Related chloro Standards
- 2-chloro-3-fluoro-4-nitro-pyridine (CAS 109613-90-3)
- 6-Chloro-2-fluoroquinoxaline (CAS 112080-05-4)
- 2-Chloro-6-fluoroquinazoline (CAS 113082-27-2)
- 6-chloro-5-fluoro-pyrimidine-4-carboxylic acid (CAS 1256785-64-4)
- 2-Chloro-7-fluoro-1,5-naphthyridine (CAS 1378470-92-8)
- 2-Chloro-8-fluoroquinazoline (CAS 1388055-06-8)
- 8-Chloro-3-fluoro-1,7-naphthyridine (CAS 1393532-49-4)
- 1-(2-Chloro-4-fluorophenyl)prop-2-yn-1-one (CAS 1477879-38-1)
Recommended Standards
- 4-Chloro-6-fluorocinnoline (CAS 2251-62-9)
- 2-chloro-4,4,5,5-tetramethyl-1,3,2-dioxaphospholane (CAS 14812-59-0)
- 2-Chloro-8-fluoroquinoxaline (CAS 55687-10-0)
- (1,2,4-Oxadiazol-3-yl)methanesulfonyl chloride (CAS 1596005-08-1)
- 8-Methyl-3,4-dihydronaphthalen-2(1H)-one (CAS 31701-18-5)
- 2-Carbamimidoylbenzo[b]thiophen-6-yl benzoate (CAS 217099-39-3)
- 1-(5-(Azepane-1-carbonyl)-4-methylthiazol-2-yl)-3-(3-chlorophenyl)urea (CAS 942010-90-4)
- Esmolol Impurity 28 DiHCl (CAS CATO-C4X-189128)
- 1-(1,4-Dioxaspiro[4.5]decan-8-yl)ethan-1-one (CAS 35477-39-5)
- Azilsartan Impurity 131 (CAS CATO-C4X-1096131)
- 1-(3-Chloro-2-methylphenyl)-2,2,3,3,3-pentafluoropropan-1-one (CAS 1352210-01-5)
- Galgravin (CAS 528-63-2)
- 2-(4-(Ethylthio)phenyl)acetic acid (CAS 3583-58-2)
- Neuropeptide Y, porcine (CAS 82785-45-3)
Why CATO?
- ISO 17034 accredited reference material producer (CNAS + ANAB dual accreditation)
- 130,000+ catalog items in stock, COA supplied with every batch
- Worldwide shipping with full export documentation (HS code guidance available)
- Technical support: +86 18665070610 / Nicole.chen@cato-chem.com