| CAS No. | 14812-59-0 |
| Molecular Formula | C6H12ClO2P |
| Molecular Weight | 182.59 g/mol |
| Category | Pharmaceutical Standards / API Standards |
| Availability | In Stock |
Compared with other compounds in its class, the molecular weight of 182.59 g/mol gives 2-chloro-4,4,5,5-tetramethyl-1,3,2-dioxaphospholane distinctive chromatographic separation conditions and mass-spectrometry parameter settings.
2-chloro-4,4,5,5-tetramethyl-1,3,2-dioxaphospholane (CAS 14812-59-0) is a high-purity analytical reference standard with the molecular formula C6H12ClO2P and a molecular weight of 182.59 g/mol.
2-chloro-4,4,5,5-tetramethyl-1,3,2-dioxaphospholane (C6H12ClO2P) contains organophosphorus functionality, a carboxylic acid group, a hydroxyl group, an ether linkage, chlorine substitution. Halogen substitution raises its density and boiling point, the carboxyl group imparts weak acidity; these physicochemical properties determine the optimal preparation and storage of its standard solutions. Halogen substitution (F/Cl/Br/I) produces a distinctive isotope pattern in mass spectrometry, a valuable aid for qualitative confirmation.
This reference standard is suitable for quantitative analysis on major chromatographic platforms including HPLC, GC, LC-MS/MS, and GC-MS, serving as an external calibration standard or a system suitability test reference material.
As a certified reference material (CRM), 2-chloro-4,4,5,5-tetramethyl-1,3,2-dioxaphospholane meets the metrological traceability requirements of ISO/IEC 17025 laboratories. Batch-to-batch consistency is monitored via control charts to guarantee comparable assigned values across lots.
| Molecular Formula | C6H12ClO2P |
| Molecular Weight | 182.59 g/mol |
| Purity | 97%+ |
| Storage | Store at 2-8°C, keep tightly closed to prevent evaporation |
| Solubility (reference) | Soluble in methanol, acetonitrile, DMSO, water (slightly soluble) |
| Stability | Contains ester bond; hydrolyzes under strong alkaline conditions |
| Degree of Unsaturation (DBE) | 0.5 |
| CAS Registry Year (est.) | 1961 |
| Halogen Content | Cl-containing |