Erythromycin EP Impurity K CAS 33442-56-7
| CAS No. | 33442-56-7 |
| Molecular Formula | C36H65NO12 |
| Molecular Weight | 703.90 g/mol |
| Category | Pharmacopoeial Impurity Standards / EP Impurities |
| Availability | In Stock |
Chemical Structure
Description
As a process- or degradation-related impurity, Erythromycin EP Impurity K (CAS 33442-56-7, C36H65NO12) is essential for impurity profiling, related-substances testing, and forced-degradation studies in pharmaceutical development.
Owing to a nitrogen-containing heterocyclic scaffold, an amide group, a hydroxyl group, an ether linkage, Erythromycin EP Impurity K is typically off-white to pale yellow amorphous powder. Its solid-state physicochemical attributes — including a molecular weight of 703.90 g/mol — guide the selection of appropriate sample preparation and analytical techniques. The aromatic system may exhibit native fluorescence, enabling detection with a fluorescence detector (FLD).
Recommended for quantitative analysis by HPLC, GC, LC-MS/MS, or GC-MS as an external calibration standard; it can also be used for spiked-recovery experiments, LOD/LOQ determination, and LC-MS/MS multiple-reaction-monitoring (MRM) calibration.
As a certified reference material (CRM), Erythromycin EP Impurity K meets the metrological traceability requirements of ISO/IEC 17025 laboratories. Batch-to-batch consistency is monitored via control charts to guarantee comparable assigned values across lots.
Physical & Chemical Properties
| Molecular Formula | C36H65NO12 |
| Molecular Weight | 703.90 g/mol |
| Purity | >90% |
| Storage | Store at room temperature, protect from light, keep sealed and dry |
| Solubility (reference) | Soluble in methanol, acetonitrile, DMSO, water (slightly soluble) |
| Stability | May oxidize slowly on prolonged air exposure; Light-sensitive; avoid direct strong light |
| Degree of Unsaturation (DBE) | 5.0 |
| UV Absorption | UV-absorbing |
| Structural Features | Aromatic ring present |
| CAS Registry Year (est.) | 1966 |
| Nitrogen Atoms | 1 |
Related Erythromycin Standards
- Erythromycin Impurity 49 (CAS 229318-98-3)
- Erythromycin Impurity 40 (CAS CATO-C4X-100140)
- Erythromycin Impurity 41 (CAS 33275-72-8)
- Erythromycin impurity 56 (CAS CATO-C4X-100156)
- Erythromycin B rearranged derivatives (CAS CATO-C4X-100170)
- Erythromycin EP Impurity E (CAS 33396-29-1)
- Erythromycin EP Impurity D (CAS 23893-13-2)
- Erythromycin EP Impurity F (CAS 105882-69-7)
Recommended Standards
- tert-Butyl 4-(2-(4-(1-benzyl-1H-benzo[d]imidazol-2-yl)phenoxy)-1-(2-phenyl-1H-benzo[d]imidazol-1-yl)ethyl)piperidine-1-carboxylate (CAS 1440754-07-3)
- Azithromycin impurity 22 (CAS CATO-C4X-100322)
- Rapamycin Impurity 14 (CAS CATO-C4X-174614)
- Azithromycin Impurity 33 (CAS CATO-C4X-100333)
- Olopatadine Impurity 4 (CAS 2519517-77-0（free base）)
- Gatifloxacin Impurity 15 (CAS 1497338-46-1)
- Linaclotide Impurity 19 (CAS CATO-C4X-210619)
- 2-Fluoro-6-(methylamino)phenol (CAS 1243287-39-9)
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- 2-(2,2-Dimethylpropanamido)-4,5-dimethoxybenzoic acid (CAS 679785-24-1)
- (1-(2-(4-Fluorophenyl)cyclopropyl)-1H-pyrazol-4-yl)methanamine hydrochloride (CAS 1956365-52-8)
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- 4-(3-Chloropropyl)-1-methyl-1h-pyrazole (CAS 1186137-01-8)
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Why CATO?
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