Rapamycin Impurity 14 CAS CATO-C4X-174614
| CAS No. | CATO-C4X-174614 |
| Molecular Formula | C38H57NO11 |
| Molecular Weight | 703.86 g/mol |
| Category | Pharmacopoeial Impurity Standards / EP Impurities |
| Availability | In Stock |
Chemical Structure
Description
Compared with other compounds in its class, the molecular weight of 703.86 g/mol gives Rapamycin Impurity 14 distinctive chromatographic separation conditions and mass-spectrometry parameter settings.
Rapamycin Impurity 14 (CAS CATO-C4X-174614) is a certified pharmaceutical impurity reference standard with the molecular formula C38H57NO11 and a molecular weight of 703.86 g/mol.
Rapamycin Impurity 14 (C38H57NO11) contains a nitrogen-containing heterocyclic scaffold, an amide group, a hydroxyl group, an ether linkage. The carboxyl group imparts weak acidity; these physicochemical properties determine the optimal preparation and storage of its standard solutions. The aromatic system may exhibit native fluorescence, enabling detection with a fluorescence detector (FLD).
Recommended for quantitative analysis by HPLC, GC, LC-MS/MS, or GC-MS as an external calibration standard; it can also be used for spiked-recovery experiments, LOD/LOQ determination, and LC-MS/MS multiple-reaction-monitoring (MRM) calibration.
The assigned purity is verified by mass-balance and quantitative NMR (qNMR) approaches, with the expanded uncertainty reported at a 95% confidence level (k=2). Batch homogeneity and stability are independently assessed for every lot.
Physical & Chemical Properties
| Molecular Formula | C38H57NO11 |
| Molecular Weight | 703.86 g/mol |
| Purity | >95% |
| Storage | Store at room temperature, protect from light, keep sealed and dry |
| Solubility (reference) | Soluble in methanol, acetonitrile, DMSO, water (slightly soluble) |
| Stability | May oxidize slowly on prolonged air exposure; Light-sensitive; avoid direct strong light |
| Degree of Unsaturation (DBE) | 11.0 |
| UV Absorption | UV-absorbing |
| Structural Features | Aromatic ring present |
| Nitrogen Atoms | 1 |
Related Rapamycin Standards
- Rapamycin Aldehyde Degrades Impurity (CAS CATO-C4X-174628)
- Rapamycin Impurity 6 (CAS 156223-31-3)
- Rapamycin Impurity 12 (CAS 150821-39-9)
- Rapamycin Impurity 19 (CAS 144293-63-0)
- Rapamycin Impurity 21 (CAS 151945-42-5)
- Rapamycin Impurity 24 (CAS CATO-C4X-174624)
- Rapamycin Impurity 25 (CAS 151945-42-5 (racemic))
- Rapamycin Dehydration Impurity (CAS CATO-C4X-174627)
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