Loxoprofen Impurity 77 CAS CATO-C4X-148877
| CAS No. | CATO-C4X-148877 |
| Molecular Formula | C17H22O5 |
| Molecular Weight | 306.35 g/mol |
| Category | Pharmacopoeial Impurity Standards / EP Impurities |
| Availability | In Stock |
Chemical Structure
Description
Under current pharmacopoeial and regulatory frameworks, quality-control requirements for this class of reference material explicitly involve the control of targets including Loxoprofen Impurity 77.
As a process- or degradation-related impurity, Loxoprofen Impurity 77 (CAS CATO-C4X-148877, C17H22O5) is essential for impurity profiling, related-substances testing, and forced-degradation studies in pharmaceutical development.
Loxoprofen Impurity 77 (C17H22O5) contains a flavonoid core, a hydroxyl group, an ether linkage. The carboxyl group imparts weak acidity; these physicochemical properties determine the optimal preparation and storage of its standard solutions. The presence of an aromatic ring or conjugated system gives the compound characteristic absorption bands in the UV-Vis region, making it well suited to UV or diode-array detection (DAD).
This reference standard supports related-substances testing and method development in line with ICH Q3A/Q3B guidance on impurity control, and is suitable for system suitability testing and forced-degradation studies.
As a certified reference material (CRM), Loxoprofen Impurity 77 meets the metrological traceability requirements of ISO/IEC 17025 laboratories. Batch-to-batch consistency is monitored via control charts to guarantee comparable assigned values across lots.
Physical & Chemical Properties
| Molecular Formula | C17H22O5 |
| Molecular Weight | 306.35 g/mol |
| Appearance | Off-white to pale yellow crystalline powder |
| Purity | 97%+ |
| Storage | Store at 2-8°C, protect from light, keep sealed and dry |
| Solubility (reference) | Soluble in methanol, acetonitrile, DMSO, water (slightly soluble) |
| Stability | May oxidize slowly on prolonged air exposure; Light-sensitive; avoid direct strong light |
| Degree of Unsaturation (DBE) | 7.0 |
| UV Absorption | UV-absorbing |
| Structural Features | Aromatic ring present |
Related Loxoprofen Standards
- Loxoprofen Impurity 78 (CAS CATO-C4X-148878)
- Loxoprofen Impurity 7 (CAS CATO-C4X-14887)
- Loxoprofen impurity 124 (CAS CATO-C4X-1488124)
- Loxoprofen Impurity 132 (CAS CATO-C4X-1488132)
- Loxoprofen Impurity 70 (CAS 1027957-36-3)
- Loxoprofen Impurity 66 (CAS 334948-52-6)
- Loxoprofen impurity 85 (CAS 335096-46-3)
- Loxoprofen Impurity 108 (CAS CATO-C4X-1488108)
Recommended Standards
- 41059-80-7 8.beta.-Acetoxy-parthenolide ACETOXYPARTHENOLIDE LIPIFEROLIDE NSC-251676 NSC251676 (CAS 41059-80-7)
- 29041-35-8 O034C3549S Matricin (3S-(3alpha,3aalpha,4alpha,9alpha,9aalpha,9bbeta))-3a,4,5,9,9a,9b-Hexahydro-9-hydroxy-3,6,9-trimethyl-2-oxoazuleno(4,5-b)-3H-furan-4-yl acetate EINECS 249-384-3 UNII-O034C3549S (CAS 29041-35-8)
- Beraprost Impurity 11 (CAS 88277-19-4)
- Triethylene glycol dimethanesulfonate (CAS 80322-82-3)
- Rasagiline Impurity 77 (CAS CATO-C4X-191377)
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- Vardenafil Impurity 63 (CAS CATO-C4X-101763)
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- sodium 5-[(hydroxymethyl)carbamoyl]pyridine-3-carboxylate (CAS 199992-66-0)
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