Fenticonazole EP Impurity B CAS 80639-94-7
| CAS No. | 80639-94-7 |
| Molecular Formula | C24H20Cl2N2O2S |
| Molecular Weight | 471.40 g/mol |
| Category | Pharmacopoeial Impurity Standards / EP Impurities |
| Availability | In Stock |
Chemical Structure
Description
Compared with other compounds in its class, the molecular weight of 471.40 g/mol gives Fenticonazole EP Impurity B distinctive chromatographic separation conditions and mass-spectrometry parameter settings.
As a process- or degradation-related impurity, Fenticonazole EP Impurity B (CAS 80639-94-7, C24H20Cl2N2O2S) is essential for impurity profiling, related-substances testing, and forced-degradation studies in pharmaceutical development.
The molecular framework of Fenticonazole EP Impurity B (C24H20Cl2N2O2S) is characterized by a steroid core, an amide group, a sulfone group, a hydroxyl group, an ether linkage, chlorine substitution. In reversed-phase chromatography, its retention is governed primarily by its high hydrophobicity (logP), which provides a practical basis for HPLC-UV/DAD or LC-MS method development. The aromatic system may exhibit native fluorescence, enabling detection with a fluorescence detector (FLD).
Recommended for quantitative analysis by HPLC, GC, LC-MS/MS, or GC-MS as an external calibration standard; it can also be used for spiked-recovery experiments, LOD/LOQ determination, and LC-MS/MS multiple-reaction-monitoring (MRM) calibration.
CATO manufactures Fenticonazole EP Impurity B under ISO 17034:2016 accreditation with dual CNAS and ANAB accreditation. Each batch is characterized by orthogonal methods and supplied with a full Certificate of Analysis (COA), ensuring metrological traceability.
Physical & Chemical Properties
| Molecular Formula | C24H20Cl2N2O2S |
| Molecular Weight | 471.40 g/mol |
| Purity | 97%+ |
| Storage | Store in a cool place (≤25°C), protect from light, keep sealed and dry |
| Solubility (reference) | Soluble in DMSO, DMF, methanol |
| Stability | May oxidize slowly on prolonged air exposure; Light-sensitive; avoid direct strong light; Hygroscopic; reseal immediately after opening; Contains ester bond; hydrolyzes under strong alkaline conditions |
| Degree of Unsaturation (DBE) | 15.0 |
| UV Absorption | UV-absorbing |
| Structural Features | Aromatic ring present |
| CAS Registry Year (est.) | 1980 |
| Halogen Content | Cl-containing |
| Nitrogen Atoms | 2 |
| Sulfur Atoms | 1 |
Related Fenticonazole Standards
- Fenticonazole EP Impurity C (CAS 80676-28-4)
- Fenticonazole Impurity 7 (CAS CATO-C4X-24917)
- Fenticonazole Impurity 6 (CAS CATO-C4X-24916)
- Fenticonazole Impurity 8 (CAS CATO-C4X-24918)
- Fenticonazole Impurity 1 (CAS 207596-23-4)
- Fenticonazole EP Impurity B Nitrate (CAS 80639-95-8)
- Fenticonazole EP Impurity C (CAS 80676-29-5)
- Fenticonazole EP Impurity D Nitrate (CAS 1313397-05-5)
Recommended Standards
- Methyl 3-amino-5,6-dimethylpyrazine-2-carboxylate (CAS 6294-72-0)
- 3-Sialylgalactose sodium salt (CAS 83563-61-5)
- Methyl 2-(2,4-dichlorobenzamido)-5-(dipropylcarbamoyl)-4-methylthiophene-3-carboxylate (CAS 335407-57-3)
- N-(2-bromophenyl)-2-((5-cyclohexyl-4-phenyl-4H-1,2,4-triazol-3-yl)thio)acetamide (CAS 332872-86-3)
- Cefuroxime Impurity 13 (CAS 229499-08-5)
- Diclofenac Impurity 28 (CAS CATO-C4X-105128)
- Fudosteine Impurity 81 (CAS CATO-C4X-144781)
- 5-(3,4-Difluorophenyl)nicotinaldehyde (CAS 1346691-73-3)
- 1-(1H-Imidazo[1,2-b]pyrazol-1-yl)ethanone (CAS 135830-23-8)
- 3,3'-Dibromo-[1,1'-biphenyl]-4,4'-diamine (CAS 34237-98-4)
- Benzyl (Chloromethyl) Succinate (CAS 143869-67-4)
- Isoquinoline-1,4-diamine dihydrochloride (CAS 1989672-45-8)
- 8-(Tert-butoxycarbonyl)-1-thia-8-azaspiro[4.5]decane-4-carboxylicacid1,1-dioxide (CAS 1373028-36-4)
- Semaglutide impurity 58 (CAS CATO-C4X-222658)
Why CATO?
- ISO 17034 accredited reference material producer (CNAS + ANAB dual accreditation)
- 130,000+ catalog items in stock, COA supplied with every batch
- Worldwide shipping with full export documentation (HS code guidance available)
- Technical support: +86 18665070610 / Nicole.chen@cato-chem.com