Methyl 2-(2-(4-chlorophenyl)acetamido)-5-((2-ethoxyphenyl)carbamoyl)-4-methylthiophene-3-carboxylate CAS 335409-31-9
| CAS No. | 335409-31-9 |
| Molecular Formula | C24H23ClN2O5S |
| Molecular Weight | 486.97 g/mol |
| Category | Pharmaceutical Standards / API Standards |
| Availability | In Stock |
Chemical Structure
Description
The occurrence of Methyl 2-(2-(4-chlorophenyl)acetamido)-5-((2-ethoxyphenyl)carbamoyl)-4-methylthiophene-3-carboxylate is closely related to a flavonoid core, an amide group, a sulfone group, a hydroxyl group, an ether linkage, chlorine substitution in its molecular formula, which determines its behaviour during synthesis, purification, or degradation.
Methyl 2-(2-(4-chlorophenyl)acetamido)-5-((2-ethoxyphenyl)carbamoyl)-4-methylthiophene-3-carboxylate (CAS 335409-31-9) is a high-purity analytical reference standard with the molecular formula C24H23ClN2O5S and a molecular weight of 486.97 g/mol.
The molecular framework of Methyl 2-(2-(4-chlorophenyl)acetamido)-5-((2-ethoxyphenyl)carbamoyl)-4-methylthiophene-3-carboxylate (C24H23ClN2O5S) is characterized by a flavonoid core, an amide group, a sulfone group, a hydroxyl group, an ether linkage, chlorine substitution. In reversed-phase chromatography, its retention is governed primarily by the protonation state of its nitrogen-containing groups, which provides a practical basis for HPLC-UV/DAD or LC-MS method development. The presence of an aromatic ring or conjugated system gives the compound characteristic absorption bands in the UV-Vis region, making it well suited to UV or diode-array detection (DAD).
This reference standard is suitable for quantitative analysis on major chromatographic platforms including HPLC, GC, LC-MS/MS, and GC-MS, serving as an external calibration standard or a system suitability test reference material.
As a certified reference material (CRM), Methyl 2-(2-(4-chlorophenyl)acetamido)-5-((2-ethoxyphenyl)carbamoyl)-4-methylthiophene-3-carboxylate meets the metrological traceability requirements of ISO/IEC 17025 laboratories. Batch-to-batch consistency is monitored via control charts to guarantee comparable assigned values across lots.
Physical & Chemical Properties
| Molecular Formula | C24H23ClN2O5S |
| Molecular Weight | 486.97 g/mol |
| Purity | 97%+ |
| Storage | Store in a cool place (≤25°C), protect from light, keep sealed and dry |
| Solubility (reference) | Soluble in DMSO, DMF, methanol |
| Stability | May oxidize slowly on prolonged air exposure; Light-sensitive; avoid direct strong light; Hygroscopic; reseal immediately after opening; Contains ester bond; hydrolyzes under strong alkaline conditions |
| Degree of Unsaturation (DBE) | 14.0 |
| UV Absorption | UV-absorbing |
| Structural Features | Aromatic ring present |
| CAS Registry Year (est.) | 2025 |
| Halogen Content | Cl-containing |
| Nitrogen Atoms | 2 |
| Sulfur Atoms | 1 |
Related Methyl Standards
- Methyl 2-(2-(4-chlorophenyl)acetamido)-5-((4-ethoxyphenyl)carbamoyl)-4-methylthiophene-3-carboxylate (CAS 505096-61-7)
- [(4-Chlorophenyl)thiomethylene]biphosphonic Acid, Tetraisopropyl Ester (CAS 89987-31-5)
- 4-(4-Chlorophenyl)-1-(4-ethylphenyl)-6-methyl-5-(3-phenyl-1,2,4-oxadiazol-5-yl)-1,2,3,4-tetrahydropyrimidine-2-thione (CAS 1169977-10-9)
- (5-(4-Chlorophenyl)-3H-[1,2,3]triazolo[4,5-b]pyridin-3-yl)(4-(3-(trifluoromethyl)phenyl)piperazin-1-yl)methanone (CAS 1072874-79-3)
- 3-(4-Chlorophenyl)-N-(3-(imidazo[1,2-a]pyridin-2-yl)phenyl)-3-(2,2,2-trifluoroacetamido)propanamide (CAS 866039-29-4)
- 3-(4-Chlorophenyl)-1-(2-nitro-4-(trifluoromethyl)phenyl)-6-(trifluoromethyl)-1H-pyrazolo[4,3-b]pyridine (CAS 338770-83-5)
- N-(((4-chlorophenyl)carbamoyl)oxy)-2,5-bis(2,2,2-trifluoroethoxy)benzamide (CAS 861208-34-6)
- 2-(4-(3-Chlorophenyl)piperazin-1-yl)-N-(2,5-dibromophenyl)acetamide (CAS 882083-72-9)
Recommended Standards
- Methyl 2-(2-(4-chlorophenoxy)acetamido)-5-((2,4-dimethylphenyl)carbamoyl)-4-methylthiophene-3-carboxylate (CAS 332923-64-5)
- Methyl 2-(2-(4-chloro-2-methylphenoxy)acetamido)-4-methyl-5-(o-tolylcarbamoyl)thiophene-3-carboxylate (CAS 504431-95-2)
- GCLE (CAS 104146-10-3)
- 1-(2-{[4-(3-chloro-4-methoxyphenyl)-5-phenyl-4h-1,2,4-triazol-3-yl]sulfanyl}acetyl)piperidine-4-carboxylic acid (CAS 731801-15-3)
- 4,6-Diethyl-1,3,5-triazin-2-amine (CAS 5599-20-2)
- 3-Bromo-6-nitro-2-(trifluoromethyl)phenol (CAS 1445995-70-9)
- (E)-2-(2,4-dichlorobenzyl)-6-(4-methylstyryl)pyridazin-3(2H)-one (CAS 1164520-09-5)
- 2-Isobutyl-9-methyl-1-oxo-2,9-dihydro-1H-beta-carboline-4-carboxylic acid (CAS 1706435-17-7)
- 1-(10H-phenothiazin-10-yl)-2-((5-(o-tolyl)-1,3,4-oxadiazol-2-yl)thio)ethan-1-one (CAS 332357-74-1)
- 3-Chloro-4-fluoro-1H-indazole-6-carboxylic acid (CAS 885521-61-9)
- 5-Chloro-3-[(2-methoxyphenyl)methyl]-1,2,4-thiadiazole (CAS 1029718-71-5)
- Tert-butyl (r)-(1-(4-chlorobenzyl)pyrrolidin-3-yl)carbamate (CAS 501116-90-1)
- 3-Carboxy-2-(icosanoyloxy)-N,N,N-trimethylpropan-1-aminium chloride (CAS 149116-07-4)
- Tau Peptide (298-312) trifluoroacetate salt (CAS 330456-47-8)
Why CATO?
- ISO 17034 accredited reference material producer (CNAS + ANAB dual accreditation)
- 130,000+ catalog items in stock, COA supplied with every batch
- Worldwide shipping with full export documentation (HS code guidance available)
- Technical support: +86 18665070610 / Nicole.chen@cato-chem.com